[Salivary minerals and caries experience among adolescents in Syktyvkar, Komi Republic].

Objective: To study the associations between salivary minerals concentrations and caries experience among adolescents in the conditions of one of the industrial centers of the Far North.

Material And Methods: In total, 146 adolescents aged 15-17 years took part in a cross-sectional study in Syktyvkar, Komi Republic. Caries experience was assessed as DMFT index and its components.

[The comparative analysis of dorsopathy morbidity of adult population in the Russian Federation and separate Subjects of the Northern-West Federal Okrug in 2013-2022].

The dorsopathy is among of common causes of restriction of human life activity, affecting one's working capacity and quality of life. The purpouse of the study was to carry out comparative analysis of dorsopathy and spondylopathy morbidity of adult population in the Russian Federation and the Subjects of the Northern-West Federal Okrug in dynamics in 2013-2022. The statistical data of the Federal State Budget Institution "The Central Research Institute for Health Organization and Informatics of Minzdrav of Russia" was used.

Polyphenolic Antioxidants in Bilberry Stems and Leaves: A Non-Targeted Analysis by Two-Dimensional NMR Spectroscopy and Liquid Chromatography-High-Resolution Mass Spectrometry.

Compared with those of berries, the stems and leaves of the genus Vaccinium are important and underestimated sources of polyphenols with high antioxidant activity. In the course of this work, aqueous methanol extracts of the aerial parts of common bilberry ( L.) and bog bilberry L.

[Prevalence of dental anomalies and need for orthodontic treatment among adults in the Arctic part of the Arkhangelsk region].

Objective: The aim of the study is to study the prevalence of dental anomalies (DA) and assess the need for orthodontic treatment (NOT) among adults in the Arctic part of the Arkhangelsk region.

Materials And Methods: In total, 1068 adult residents of Arkhangelsk and Primorski rural district aged 35-90 years took part in a cross-sectional study. The Dental Aesthetic Index (DAI) was used to assess the prevalence of DA and NOT in the study population.

Analysis of pentacyclic triterpenoids and phytosterols in cloudberry () by LC-MS/MS.

Cloudberry (.) is a plant rich in various biologically active compounds. In this work, the composition and concentrations of pentacyclic triterpenoids (PCTs) and phytosterols in various parts of cloudberries were studied using high-performance liquid chromatography-tandem mass spectrometry by multiple reaction monitoring mode (MRM, targeted analysis) and precursor ion scan mode (non-targeted analysis and semi-quantitative determination).

[The application of information technologies in system of support of decision making in osteopathy].

The implementation of information technologies into treatment practice of modern health care significantly increases efficiency of diagnosis and treatment of dorsopathies. The purpose of the study is to develop software module to evaluate post-urological status of patients with spine dorsopathy to optimize diagnostic process and treatment planning. The article describes application of original software module to assess the post-urological status of patients with spine dorsopathy.

[The venereal morbidity in Russia in 1914-1924].

It is accepted to explain increasing of venereal diseases during years of the Revolution by degradation of morality and general disorder of system of state administration and sanitary services in Russia. The cross-verification of information presented in scientific publications and primary information sources makes it possible to look into following issues: degree of venereal (syphilitic) contamination of population of pre-revolutionary Russia; influence on sanitary statistics by erroneous diagnostics and convictions of Zemstvo medicine about predominantly non-sexual path of transmission of syphilis pathogen in Russian countryside; dynamics and sources of venereal morbidity in wartime. The high indicators of pre-revolutionary statistics of venereal infections could be affected by diagnostic errors.

Polycommunin A, a dihydrocinnamoyl bibenzyl isolated from the moss and its antioxidant activity.

A novel polyphenolic compound named Polycommunin A (1) was discovered in the aerial part of the common haircap moss () widely spread in boreal and temperate climate zones. Aqueous ethanol and extraction of the plant material with further isolation of polyphenolic fraction and preparative HPLC separation allowed obtaining individual compound and identifying it as dimeric dihydrocinnamoyl bibenzyl by NMR spectroscopy and high-resolution tandem mass spectrometry. Polycommunin A demonstrated high antioxidant activity determined by FRAP and PCL assays and comparable to that of Trolox and Quercetin.

Resolution-enhanced Kendrick mass defect analysis for improved mass spectrometry characterization of lignin.

Lignin is a promising renewable source of valuable organic compounds and environmentally benign materials. However, its involvement in economic circulation and the creation of new biorefining technologies require an understanding of its chemical composition and structure. This problem can be overcome by applying mass spectrometry analytical techniques in combination with advanced chemometric methods for mass spectra processing.

Mucolytic Drugs Ambroxol and Bromhexine: Transformation under Aqueous Chlorination Conditions.

Bromhexine and ambroxol are among the mucolytic drugs most widely used to treat acute and chronic respiratory diseases. Entering the municipal wastewater and undergoing transformations during disinfection with active chlorine, these compounds can produce nitrogen- and bromine-containing disinfection by-products (DBPs) that are dangerous for aquatic ecosystems. In the present study, primary and deep degradation products of ambroxol and bromhexine obtained in model aquatic chlorination experiments were studied via the combination of high-performance liquid and gas chromatography with high-resolution mass spectrometry.

Isobornyl and Isocamphyl Photostabilizers in Poly(lactic acid)-Based Electrospun Fibers.

In this work, electrospun polylactide fibers with new photostabilizing additives, 4-methyl-2,6-diisobornylphenol (DIBP) and N-isocamphylaniline (NICA), have been tested under the influence of UV-C radiation (254 nm). The changes in the polymers' chemical structure under UV-C radiation were revealed through the increase in absorption in the 3600-3100 cm region in regard to the FTIR spectra. In the samples that were irradiated for 1 h, the stabilizing effect of the photoprotectors became most noticeable as the difference in the content of the hydroxyl groups in stabilized and the pure PLA reached a maximum.

[Statistical modeling of the fact and requests frequency for emergency medical care by primary care different age groups patients.].

The frequency of seeking emergency medical care (EC) can be mediated by the characteristics of the patient's social status, his health literacy (HL) but not only by the clinical signs of the disease, health status. The goal of the cross-sectional survey was to identify factors determining the frequency of applying for EC by the young-aged, middle-aged (18-59 years) and elderly (60-74 years) patients of the primary health organizations in the Arkhangelsk Region and the Komi Republic (North-West Russia). Logistic regression (LR) was used to identify factors mediating the fact of applying for EC; zero-inflated negative binomial regression (ZINB) - to identify factors mediating the frequency of appeals.

Analysis of Softwood Lignans by Comprehensive Two-Dimensional Liquid Chromatography.

Lignans constitute a large group of phenolic plant secondary metabolites possessing high bioactivity. Their accurate determination in plant extracts with a complex chemical composition is challenging and requires advanced separation techniques. In the present study, a new approach to the determination of lignans in coniferous knotwood extracts as the promising industrial-scale source of such compounds based on comprehensive two-dimensional liquid chromatography separation and UV spectrophotometric detection is proposed.

[Continuing work after 64 years of age and postural balance.].

The objective of this study was to assess the components of postural balance among working and non-working men and women aged 65-69. A total of 120 people within the age range of 65-69 were screened. The first group included 30 female and 30 male patients who continued working beyond retirement.

[Older age vitality and retirement (literature review).].

The article provides a review of research literature on the social and psychological peculiarities of working and non-working pensioners with additional new data on their life quality. Six psychographic profiles of pensioners based on their post-retirement activities and motivations for new life path choices were described and examined, enabling identification of the subjects' personality types. These data are essential for psychologists and social workers consulting people approaching retirement age and recent retirees on their retirement lifestyle, ways to organize their working life and effective (creative) pastime, including career development later in life, without sacrificing their physical and mental health.

Application of 2D NMR Spectroscopy in Combination with Chemometric Tools for Classification of Natural Lignins.

Lignin is considered a promising renewable source of valuable chemical compounds and a feedstock for the production of various materials. Its suitability for certain directions of processing is determined by the chemical structure of its macromolecules. Its formation depends on botanical origin, isolation procedure and other factors.

Kendrick mass defect analysis - a tool for high-resolution Orbitrap mass spectrometry of native lignin.

Lignin is the second most abundant biopolymer in nature and a promising renewable feedstock for the production of aromatic compounds, composite materials, sorbents, etc. Being a complex mixture of oligomeric molecules with an irregular structure, natural lignin is an extremely difficult object to study. Its molecular level characterization requires advanced analytical techniques among which atmospheric pressure photoionization Orbitrap mass spectrometry holds a promising place.

Determination of Pentacyclic Triterpenoids in Plant Biomass by Porous Graphitic Carbon Liquid Chromatography-Tandem Mass Spectrometry.

Pentacyclic triterpenoids (PCTs), which possess a number of bioactive properties, are considered one of the most important classes of secondary plant metabolites. Their chromatographic determination in plant biomass is complicated by the need to separate a large number of structurally similar compounds belonging to several classes that differ greatly in polarity (monools, diols, and triterpenic acids). This study proposes a rapid, sensitive, and low-cost method for the simultaneous quantification of ten PCTs (3-taraxerol, lupeol, -amyrin, -amyrin, betulin, erythrodiol, uvaol, betulinic, oleanolic, and ursolic acids) by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) using porous graphitic carbon (Hypercarb) as a stationary phase capable of hydrophobic retention and specific interactions with analytes.

New Oligomeric Dihydrochalcones in the Moss : Identification, Isolation, and Antioxidant Activity.

One of the most widespread representatives of mosses in the temperate and boreal latitudes of the Northern Hemisphere is common haircap (), which is known as the largest moss in the world and widely used in traditional herbal medicine. Polyphenolic compounds constitute one of the most important groups of biologically active secondary metabolites of , however, the available information on their chemical composition is still incomplete and contradictory. In the present study, a group of dihydrochalcone polyphenolic derivatives that were not previously found in mosses was isolated from biomass using pressurized liquid extraction with aqueous acetone.

Data of polycyclic aromatic hydrocarbons concentration in the Siberian Arctic seas sediments.

Polycyclic Aromatic Hydrocarbons (PAHs) are one of the most dangerous persistent organic pollutants in the Arctic. They have different sources and pathways of entering in to the environment. Because of their lipophilic properties, PAHs can easily accumulate in marine sediments.

Rapid determination of phthalates in paper products by supercritical fluid chromatography/tandem mass spectrometry.

Phthalic acid esters are widely used as components of industrial and consumer products including paper and cardboard packaging materials in contact with food or human skin. Being endocrine-disrupting chemicals, phthalic acid esters have a negative effect on human health and must be controlled in pulp and paper products. In the present study, supercritical fluid chromatography-tandem mass spectrometry in combination with pressurized liquid extraction was proposed for phthalic acid esters determination in such objects.

Supercritical Fluid Chromatography-Tandem Mass Spectrometry for Rapid Quantification of Pentacyclic Triterpenoids in Plant Extracts.

Pentacyclic triterpenoids (PCTs) are a widely distributed class of plant secondary metabolites. These compounds have high bioactive properties, primarily antitumor and antioxidant activity. In this study, a method was developed for the quantitative analysis of pentacyclic triterpenoids in plants using supercritical fluid chromatography-tandem mass spectrometry (SFC-MS/MS).

Polycyclic aromatic hydrocarbons in the Siberian Arctic seas sediments.

Polycyclic Aromatic Hydrocarbons (PAHs) are among the main persistent organic pollutants in the Arcticwhich enter the polar region from lower latitudes by air transport and ocean currents and accumulate in marine sediments. This work represents the first study in 25 years of the least studied and hard-to-reach areas of Siberian arctic seas. Sixteen priority PAHs as well as 1- and 2-methylnaphthalenes were analyzed by gas chromatography - tandem mass spectrometry in the twenty-four sediment samples taken from Kara, Laptev and East Siberian Seas in October 2020.

Features of the Chemical Composition and Structure of Birch Phloem Dioxane Lignin: A Comprehensive Study.

Understanding the chemical structure of lignin in the plant phloem contributes to the systematics of lignins of various biological origins, as well as the development of plant biomass valorization. In this study, the structure of the lignin from birch phloem has been characterized using the combination of three analytical techniques, including 2D NMR, Py-GC/MS, and APPI-Orbitrap-HRMS. Due to the specifics of the phloem chemical composition, two lignin preparations were analyzed: a sample obtained as dioxane lignin (DL) by the Pepper's method and DL obtained after preliminary alkaline hydrolysis of the phloem.