Exploring salinity induced adaptations in marine diatoms using advanced photonic techniques.

Photonic-based methods are crucial in biology and medicine due to their non-invasive nature, allowing remote measurements without affecting biological specimens. The study of diatoms using advanced photonic methods remains a relatively underexplored area, presenting significant opportunities for pioneering discoveries. This research provides a comprehensive analysis of marine diatoms, specifically Nitzschia sp.

Description of Encyonemataceae fam. nov. and Witkowskiaceae fam. nov. (Bacillariophyceae, Cymbellales) based on molecular and morphological analyses.

In this study, based on the results of molecular analysis of SSU rRNA and rbcL sequences, we propose the descriptions of two new families in the order Cymbellales. Molecular data demonstrates that diatoms of the genus Encyonema constitute an independent monophyletic clade, which represents a new family described herein - Encyonemataceae fam. nov.

Buckyballs to fight pandemic: Water-soluble fullerene derivatives with pendant carboxylic groups emerge as a new family of promising SARS-CoV-2 inhibitors.

Herein, we present the first experimental study of individual water-soluble fullerene derivatives proving their ability to inhibit SARS-CoV-2 in vitro. The initial screening allowed us to identify a few new compounds that have demonstrated pronounced antiviral activity with IC values as low as 390 nM and selectivity indexes reaching 214. Time-of-addition analysis and molecular docking results suggested that the viral protease and/or the spike protein are the most probable targets inhibited by the fullerene derivatives.

Proposal of Crystallibacter gen. nov., Crystallibacter permensis sp. nov. and Crystallibacter degradans sp. nov. for the salt-tolerant and aromatics degrading actinobacteria, and reclassification of Arthrobacter crystallopoietes as Crystallibacter crystallifaciens comb. nov.

Four salt-tolerant and aromatics degrading strains used in this study were isolated from polluted technogenic soil on the territory of the Verkhnekamsk potash deposit (Russia). The strains were aerobic, Gram-stain-positive, non-motile, non-endospore-forming irregular rods, exhibiting a marked rod-coccus growth cycle. They contained lysine-based peptidoglycan, teichulosonic acid and poly(glycosyl phosphate) polymers in the cell walls.

Hibernation enhances contractile responses of basilar artery in ground squirrels: The role of rho-kinase and NO.

Hibernation is accompanied by dramatic decrease of blood flow in many organs due to the increase of their vascular resistances. We compared the responses of mesenteric, renal, and cerebral proximal resistance arteries in summer active (SA) and winter hibernating (WH) ground squirrels and studied the signaling pathways of Rho-kinase and NO. Wire myography and Western blotting were used to assess the arterial responses and protein abundances.

YAP/TAZ Signalling Controls Epidermal Keratinocyte Fate.

The paralogues Yes-associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) control cell proliferation and cell fate determination from embryogenesis to ageing. In the skin epidermis, these proteins are involved in both homeostatic cell renewal and injury-induced regeneration and also drive carcinogenesis and other pathologies. YAP and TAZ are usually considered downstream of the Hippo pathway.

Diverse Cyclization Pathways Between Nitriles with Active -Methylene Group and Ambiphilic 2-Pyridylselenyl Reagents Enabled by Reversible Covalent Bonding.

Herein, we describe a novel coupling between ambiphilic 2-pyridylselenyl reagents and nitriles featuring an active α-methylene group. Depending on the solvent employed, this reaction can yield two distinct types of cationic pyridinium-fused selenium-containing heterocycles, 1,3-selenazolium or 1,2,4-selenadiazolium salts, in high yields. This is in contrast to what we observed before for other nitriles.

Non-Contact Interaction Between Phorbol Myristate Acetate and Aqueous Alcohol Solutions Under Combined Magnetic Fields.

Previous research has demonstrated that a combined magnetic field (CMF) plays a critical role in modifying the properties of aqueous solutions, leading to an increase in the luminol-enhanced chemiluminescence of neutrophils. Using this model, the distant interaction between aqueous solutions was demonstrated, and the role of a CMF in the regulation of this phenomenon was established. In the current study, highly diluted (HD) phorbol myristate acetate (PMA) solution (the donor) was incubated with aqueous ethanol (the acceptor), both in a CMF-generating device and under geomagnetic field (GMF), for 0, 20, and 60 min.

Molecular and morphological investigations of two new species in Qinia and Cymbella (Bacillariophyceae: Cymbellales) from China.

Molecular data is provided firstly for the newly erected genus Qinia, and the phylogenetic position of the genus Qinia within the Cymbellales is discussed. Despite the presence of apical pore fields bisected by the distal raphe fissure being a very distinctive feature for Qinia, molecular analysis demonstrates this character as homoplasious, having evolved independently in Qinia and Cymbella. Two new species, Qinia hubeii sp.

Branchiopoda (Crustacea: Anostraca and Diplostraca) diversity in Tajik Pamir and plain West and South Tajikistan.

Here we attempt to clarify a faunistic composition of branchiopods from southern Tajikistan and the southern part of the Tajik Pamir Plateau (Central Asia) based on samples collected from June 24 to July 6, 2023. In total, 19 species of branchiopods were identified from plain West and South Tajikistan, and 27 species were recorded in Tajik Pamir. Five taxa were newly recorded for the territory of Tajikistan: Chirocephalus cf.

Is it possible to use the male calling signal analysis for species diagnostics in Dictyophara Germar, 1833 (Hemiptera: Fulgoroidea: Dictyopharidae)?

Comparative analysis of the male calling signals of five species of Dictyophara showed that signals of different species do not differ either in oscillograms and frequency spectra or in the mean values and ranges of the pulse repetition period. D. europaea differs from four other species by the specific trend of the pulse repetition period change from the beginning to the end of signal; signals of D.

A checklist of Eucnemidae (Coleoptera: Elateroidea) from Iran.

The distribution of Eucnemidae (Coleoptera: Elateroidea) of Iran is summarized and an annotated checklist of the Iranian Eucnemidae is provided. A total of 16 species within 13 genera in four subfamilies of the family are listed.

Leafhoppers of the genus Kybos Fieber, 1866 (Hemiptera: Cicadellidae: Typhlocybinae: Empoascini) in Kyrgyzstan.

Illustrated descriptions of six Kybos species found in Kyrgyzstan are provided, with data on biology and distribution. Oscillograms of the male vibrational calling signals are presented for four species. The synonymies K.

A new species of the genus Ovalona Van Damme & Dumont, 2008 (Cladocera: Anomopoda: Chydoridae) from South-East Asia, related to Australian Ovalona archeri (Sars, 1888).

A new species of Ovalona Van Damme & Dumont, 2008 (Cladocera: Anomopoda) related to the rare Australian species Ovalona archeri (Sars, 1888), is described from the Mekong Delta, South Vietnam. Ovalona garibiani sp. nov.

Free-living marine nematodes of the family Sphaerolaimidae (Chromadoria, Monhysterida) from the mangroves of the Qeshm Island, Persian Gulf.

Three species of the family Sphaerolaimidae were found and are described for the first time along the coast of the Qeshm Island. Sphaerolaimus qeshmensis sp. n.

New data on two rare East Asian cladocerans, Coronatella trachystriata (Chen, Zhang & Liu, 1994) and Nedorhynchotalona chiangi Kotov & Sinev, 2011 (Cladocera: Anomopoda: Chydoridae).

Two rare East Asian cladocerans, Coronatella (Coronatella) trachystriata (Chen, Zhang et Liu, 1994) and Nedorhynchotalona chiangi Kotov & Sinev, 2011, were found in Qili Lake on the border of Anhui and Jiangsu Provinces of China. Morphology of the species was studied by scanning electron microscopy for the first time, revealing unique morphological features: valve sculpture as a system of ridges in C. (C.

[On the issue of determining notions "medical malpractice", "yatrogeny" and "defect of medical care": social legal aspects].

The article considers social legal aspects of concepts of "medical error", "iatrogenesis", "defect of medical care" in view of absence of their clear definition and understanding in public and professional communities. The usage of these concepts is distinguished by chronological continuity that is conditioned by influence of approaches existed at different stages. On the basis of analysis of scientific publications and normative legal base their genesis and peculiarities of definition are demonstrated.

Description of Wickerhamia europaea sp. nov. and revisitation of the ascospore number of W. fluorescens.

During the course of two independent studies, six conspecific yeast strains were recovered from flowers, soil, bird faeces and wood of different geographical origins. The six strains share identical DNA sequences in two barcoding regions, the D1/D2 domain of the LSU rRNA gene and the internal transcribed spacer (ITS) region (ITS1-5.8S rRNA gene-ITS2).

Comparative Effect of Insulin Resistance Reduction and Hormonal Alterations on Type 2 Diabetes Remission After Bariatric Surgery.

Bariatric surgery is known to induce weight loss and diabetes remission in patients with type 2 diabetes (T2D), but the exact mechanism of glycemic normalization needs to be defined. The study included patients with BMI ≥ 35 kg/m, obesity history ≥ 10 years, and planned bariatric surgery. At baseline and 3 and 6 months after surgery, all patients underwent anthropometric measurements, body composition and blood tests (including insulin, glucagon, and incretins during oral glucose tolerance test (OGTT)), and hyperinsulinemic euglycemic clamp tests.

Matrikines of Sea Cucumbers: Structure, Biological Activity and Mechanisms of Action.

Matrikines (MKs), the products of enzymatic fragmentation of various extracellular matrix (ECM) proteins, regulate cellular activity by interacting with specific receptors. MKs affect cell growth, proliferation, and migration, can induce apoptosis and autophagy, and are also effectively used in biomedicine and functional nutrition. Recently, there has been great interest in the structural features and biological activity of MKs from various sources.

The Role of Neuropeptide Y in the Pathogenesis of Alzheimer's Disease: Diagnostic Significance and Neuroprotective Functions.

. Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. It has been suggested that the factors that cause pathologic changes and lead to the development of AD may also include changes in certain neuropeptides.

Antioxidant properties of the soluble carotenoprotein AstaP and its feasibility for retinal protection against oxidative stress.

Photodamage to the outer segments of photoreceptor cells and their impaired utilization by retinal pigment epithelium (RPE) cells contribute to the development of age-related macular degeneration (AMD) leading to blindness. Degeneration of photoreceptor cells and RPE cells is triggered by reactive oxygen species (ROS) produced by photochemical reactions involving bisretinoids, by-products of the visual cycle, which accumulate in photoreceptor discs and lipofuscin granules of RPE. Carotenoids, natural antioxidants with high potential efficacy against a wide range of ROS, may protect against the cytotoxic properties of lipofuscin.