1 results match your criteria: "M.S.)-Center for Veterinary Medicine[Affiliation]"
Influence of ABCB1 Genotype in Collies on the Pharmacokinetics and Pharmacodynamics of Loperamide in a Dose-Escalation Study.
Drug Metab Dispos
September 2015
Office of Research, Division of Applied Veterinary Research (M.J.M., H.F.Y.); Office of New Animal Drug Evaluation, Division of Scientific Support (J.Q) Office of New Animal Drug Evaluation (M.M.); Office of Research, Division of Residue Chemistry (H.L.); Office of New Animal Drug Evaluation, Division of Therapeutic Drugs for Non-Food Animals (L.T., M.S.)-Center for Veterinary Medicine,US Food and Drug Administration, Silver Spring, Maryland.
Thirty-three Collies (14 male and 19 female) were used in a dose-escalation study to determine the impact of ABCB1 genotype on loperamide pharmacokinetics (PK) and pharmacodynamics (PD). Loperamide was orally administered in four ascending doses (0.01, 0.
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