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This study compared the clinical effects of 0.05% metronidazole solution (MD) applied subgingivally using pulsated monojet irrigation following a single episode of scaling and root planing and simplified oral hygiene instruction, with the same system using a placebo solution (MDP). Twelve patients with 129 approximal units (pocket depth greater than or equal to 4 mm) in the MD group and 170 in the MDP group took part in the study.
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