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Objective: The etiology of nicotinic stomatitis is strongly linked with nicotine compounds; however, high temperature can be synergistic to the damage of tobacco compounds. The aim of the present study was to evaluate the separate and combined effects of smoking and heat applied by hot drinks as predictors for the development of nicotinic stomatitis in a population from southern Brazil.

Method And Materials: In a case-control study, 53 patients of both sexes with a median age of 43 years (18 to 83 years) with the clinical diagnosis of nicotinic stomatitis were selected consecutively.

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