4,343 results match your criteria: "Lumbar Spondylolysis and Spondylolisthesis"

Article Synopsis
  • Lumbar spinal stenosis (LSS) and spondylolisthesis (SPL) are similar degenerative spinal conditions that have different recommendations regarding exercise, making it challenging to study the impact of physical activity on them.
  • This study examined the effects of restricted physical activity due to social distancing during the pandemic on healthcare visits and costs for patients with LSS and SPL, comparing data from the pandemic period to pre-pandemic.
  • Results showed a significant decrease in hospital visits for both LSS and SPL patients after the implementation of social distancing, with LSS patients also experiencing a notable reduction in medical costs, while SPL patients did not see a significant change in costs.
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Article Synopsis
  • The study aimed to compare the muscle structure of paraspinal muscles in patients with degenerative spondylolisthesis (DS), isthmic spondylolisthesis (IS), and healthy individuals.
  • Researchers measured factors like cross-sectional area and fatty infiltration in these muscles, with a focus on differences based on occupation (workers vs. farmers).
  • Results showed that both DS and IS patients had atrophy in the multifidus muscle compared to healthy individuals, but IS patients also exhibited hypertrophy in the erector spinae muscle, highlighting the need for tailored surgical approaches based on muscle morphology variations in spondylolisthesis types.
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Background: The rise of minimally invasive lumbar fusions and advanced imaging technologies has facilitated the introduction of novel surgical techniques with the trans-facet approach being one of the newest additions. We aimed to quantify any pathology-driven anatomic changes to the trans-facet corridor, which could thereby alter the ideal laterality of approach to the disc space.

Methods: In this retrospective cohort study, we measured the areas and maximum permissible cannula diameters of the trans-facet corridor using commercially available software (BrainLab, Munich, Germany).

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Objective: To compare the effectiveness of unilateral biportal endoscopic transforaminal lumbar interbody fusion (UBE-TLIF) and endoscopic transforaminal lumbar interbody fusion (Endo-TLIF) in the treatment of single-segment degenerative lumbar spinal stenosis with lumbar spondylolisthesis.

Methods: Between November 2019 and May 2023, a total of 81 patients with single-segment degenerative lumbar spinal stenosis with lumbar spondylolisthesis who met the selection criteria were enrolled. They were randomly divided into UBE-TLIF group (39 cases) and Endo-TLIF group (42 cases).

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Article Synopsis
  • This study compared the surgical and clinical outcomes of two procedures—minimally invasive transforaminal lumbar interbody fusion (MIS TLIF) and midline lumbar interbody fusion (MIDLIF)—in patients with spondylolisthesis.
  • Results showed that while both procedures had similar fusion rates and recovery times, MIDLIF was associated with a shorter operation time and lower pain scores post-surgery compared to MIS TLIF.
  • Additionally, the MIS TLIF group experienced a higher rate of facet joint violations, while other complications were similar across both groups.
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Background: The comparative effectiveness of decompression plus lumbar facet arthroplasty versus decompression plus instrumented lumbar spinal fusion in patients with lumbar spinal stenosis and grade-I degenerative spondylolisthesis is unknown.

Methods: In this randomized, controlled, Food and Drug Administration Investigational Device Exemption trial, we assigned patients who had single-level lumbar spinal stenosis and grade-I degenerative spondylolisthesis to undergo decompression plus lumbar facet arthroplasty (arthroplasty group) or decompression plus fusion (fusion group). The primary outcome was a predetermined composite clinical success score.

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Article Synopsis
  • The study aimed to assess the safety and effectiveness of a new method for correcting high-grade spondylolisthesis (HGS) in kids through formal reduction and circumferential fusion.
  • It involved 29 children, and their results were measured using various radiographic analyses and quality of life assessments before and after surgery.
  • The findings indicated a significant reduction in slip percentage and improvements in radiological measurements and overall quality of life, suggesting that the procedure is safe and beneficial for young patients with HGS.
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Article Synopsis
  • The study investigated the effects of the OLIF surgical technique on spinal-pelvic alignment and its relationship with clinical outcomes in patients with degenerative lumbar spondylolisthesis.
  • A total of 43 patients were analyzed, with significant improvements observed in pain levels and disability scores after surgery, indicating successful outcomes (P < .05).
  • Pearson correlation analysis showed a positive relationship between changes in specific spinal parameters (like LL and FH) and improvements in clinical scores (VAS and ODI), suggesting that surgical success leads to better alignment and patient outcomes.
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Article Synopsis
  • The study used a retrospective cohort design to find factors that predict slower or no improvement after surgery for L4-5 degenerative lumbar spondylolisthesis (DLS).
  • It focused on various clinical and radiological measures, assessing a range of predictor variables including patient demographics, comorbidities, and specific surgical outcomes over a minimum of 1 year.
  • Key findings showed that certain factors like pelvic tilt, depression, VAS leg scores, and facet orientation impacted improvement outcomes both in the short and long term after surgery.
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Three Stages on Magnetic Resonance Imaging of Lumbar Degenerative Spine.

World Neurosurg

July 2024

Department of Orthopedic Surgery, Spine Center, Changzheng Hospital, Naval Medical University, Shanghai, People's Republic of China. Electronic address:

Purposes: To propose a new lumbar degenerative staging system using the current radiological classification system.

Methods: A cross-sectional analysis of retrospective databases between January 2018 and December 2022 was performed. Total of 410 patients for Modic changes, paravertebral muscle fat infiltration, disc degeneration, articular process degeneration, vertebral endplate degeneration and other structures, and disc displacement, Spondylolisthesis, and stenosis, and grouped patients according to stage were assessed.

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Objective: In this study, the authors aimed to determine the mid- to long-term outcomes of microendoscopic laminotomy (MEL) for lumbar spinal stenosis (LSS) with degenerative spondylolisthesis (DS) and identify preoperative predictors of poor mid- to long-term outcomes.

Methods: The authors retrospectively reviewed the medical records of 274 patients who underwent spinal MEL for symptomatic LSS. The minimum postoperative follow-up duration was 5 years.

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Objective: In the treatment of lumbar degenerative spondylolisthesis (LDS) with Posterior lumbar interbody fusion (PLIF) surgery, interbody fusion implants play a key role in supporting the vertebral body and facilitating fusion. The objective of this study was to assess the impact of implantation depth on sagittal parameters and functional outcomes in patients undergoing PLIF surgery.

Methods: This study reviewed 128 patients with L4-L5 LDS between January 2016 and August 2019.

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A Comparison of 2 Cage Sizes in Biportal Endoscopic Transforaminal Lumbar Interbody Fusion.

Clin Spine Surg

December 2024

Department of Orthopedic Surgery, Michigan Orthopedic Surgeons, Southfield, MI.

Study Design: Retrospective study.

Objective: This study compared the fusion and subsidence rate and clinical outcomes when using different-sized static PEEK cages in BE-TLIF.

Summary Of Background Data: Biportal endoscopic techniques for transforaminal lumbar interbody fusion (BE-TLIF) have been shown to have similar clinical and fusion outcomes with faster clinical recovery in comparison to tubular surgery.

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Risk factors for early-onset adjacent segment degeneration after one-segment posterior lumbar interbody fusion.

Sci Rep

April 2024

Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, 23-3 Matsuoka Shimoaizuki, Eiheiji-cho, Yoshida-gun, Fukui, 910-1193, Japan.

Article Synopsis
  • Adjacent segment degeneration (ASD) is a common complication after posterior lumbar interbody fusion (PLIF), with early-onset ASD differing from late-onset forms.
  • A study on 170 patients with L4 degenerative spondylolisthesis found a 20.6% rate of early-onset ASD within 2 years post-surgery, linked to specific risk factors.
  • Key risk factors identified include preoperative larger % slip, vertebral bone marrow edema on preoperative MRI (odds ratio 16.8), and significant surgical disc space distraction, emphasizing the importance of careful assessment before fusion surgery.
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Background: Substantial variation exists in surgeon decision making. In response, multiple specialty societies have established criteria for the appropriate use of spine surgery. Yet few strategies exist to facilitate routine use of appropriateness criteria by surgeons.

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The Classification of Lumbar Spondylolisthesis X-Ray Images Using Convolutional Neural Networks.

J Imaging Inform Med

October 2024

Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Three Gorges University, Yichang, 443002, Hubei, China.

Article Synopsis
  • Researchers created and tested a deep convolutional neural network (DCNN) model to identify conditions like spondylolysis and spondylolisthesis using X-ray images of the lumbar region.
  • They analyzed 2449 X-ray images, categorizing them into normal and abnormal cases, and used the EfficientNetV2-M network to train the model on these images.
  • The DCNN model outperformed human diagnoses, achieving a 92% accuracy, and its performance was visually analyzed using Grad-CAM to highlight important areas for detection.
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Objective: This study aimed to evaluate preoperative (pre-op) radiographic characteristics and specific surgical interventions in patients with degenerative lumbar spondylolisthesis (DLS) who underwent lumbar fusion surgery (LFS), with a focus on analyzing predictors of postoperative restoration of segmental lumbar lordosis (SLL).

Methods: A retrospective review at a single center identified consecutive single-level DLS patients who underwent LFS between 2016 and 2022. Radiographic measures included disc angle (DA), SLL, lumbar lordosis (LL), anterior/posterior disc height (ADH/PDH), spondylolisthesis percentage (SP), intervertebral disc degeneration, and paraspinal muscle quality.

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Association between vertebral endplate defects and patient-reported symptoms: an immunohistochemical study investigating the COX-2/PGE-2/EP-4 axis.

Spine J

August 2024

Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. Electronic address:

Article Synopsis
  • Vertebral endplate defects may be linked to degenerative disc disorders, but their impact on patient-reported symptoms is not well understood, highlighting the need for this study.
  • The research aims to explore the relationship between endplate defects and chronic low back pain, particularly focusing on the role of inflammatory markers COX-2, PGE-2, and the EP-4 receptor in patients' experiences of pain.
  • The study included 71 patients who had specific surgeries, measuring various outcomes such as pain levels and endplate defect scores to determine differences between those with and without defects.
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Purpose: This study aimed to examine the vertebral body shape characteristics and spondylopelvic alignment in L4 degenerative spondylolisthesis (DS) as well as the risk factors for the development of DS.

Methods: This cross-sectional study compared vertebral morphology and sagittal spinopelvic alignment in female patients with lumbar DS and lumbar spinal stenosis (LSS). The degree of lumbar lordosis (LL), pelvic incidence (PI), cross-sectional area (CSA), and vertebral body height ratio (ha/hp) of the lumbar spine were compared using full-length spine radiographs and computed tomography in 60 females with DS and in 60 women with LSS.

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Objective: To systematically evaluate the difference in clinical efficacy between two surgical approaches, oblique lateral approach and intervertebral foraminal approach, in the treatment of degenerative lumbar spondylolisthesis.

Methods: English databases, including PubMed, Cochrane, Embase, and Web of Science, were systematically searched using keywords such as "oblique lumbar interbody fusion" and "transforaminal lumbar interbody fusion." Concurrently, Chinese databases, including CNKI, WanFang data, VIP, and CBM, were also queried using corresponding Chinese terms.

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Background: In case of high sacral slope, anterior lumbosacral fusions can be performed by retroperitoneal or transperitoneal approach using a reversed Bohlman technique with an autologous corticocancellous fibular graft. The use of a trans-lumbosacral implant can avoid the iatrogenic effects but currently, there is no implant specifically designed for this fusion technique. Could the IFUSE implant from SI BONE replace a fibular graft to avoiding the iatrogenic effect induced by sampling during a Reverse Bohlman technique?

Patients And Methods: We present the case of a 38-year-old woman with L5S1 interbody pseudarthrosis after posterior fixation for grade 2 L5-S1 spondylolisthesis with isthmic lysis of L5, and that of a 69-year-old woman who underwent a posterior T4 fusion to the pelvis for degenerative scoliosis.

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Two-Stage Deep Learning Model for Diagnosis of Lumbar Spondylolisthesis Based on Lateral X-Ray Images.

World Neurosurg

June 2024

Department of orthopedics, Beijing Tongren Hospital, Capital Medical University, Beijing, China. Electronic address:

Background: Diagnosing early lumbar spondylolisthesis is challenging for many doctors because of the lack of obvious symptoms. Using deep learning (DL) models to improve the accuracy of X-ray diagnoses can effectively reduce missed and misdiagnoses in clinical practice. This study aimed to use a two-stage deep learning model, the Res-SE-Net model with the YOLOv8 algorithm, to facilitate efficient and reliable diagnosis of early lumbar spondylolisthesis based on lateral X-ray image identification.

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Study Design: Retrospective cohort.

Objective: To determine if performing a simultaneous laminectomy at an unfused level adjacent to an instrumented fusion increases the risk of adjacent segment disease (ASD).

Summary Of Background Data: Laminectomy adjacent to instrumented fusion has uncertain outcomes.

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Background And Objectives: Studies have demonstrated increased risk of adjacent segment disease (ASD) after open fusion with adjacent-level laminectomy, with rates ranging from 16%-47%, potentially related to disruption of the posterior ligamentous complex. Minimally invasive surgical (MIS) approaches may offer a more durable result. We report institutional outcomes of simultaneous MIS transforaminal lumbar interbody fusion (MISTLIF) and adjacent-level laminectomy for patients with low grade spondylolisthesis and ASD.

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The relationship between paraspinal muscle atrophy and degenerative lumbar spondylolisthesis at the L4/5 level.

Spine J

August 2024

Department of Orthopaedic Surgery, Hospital for Special Surgery, Weill Cornell Medicine, 525 East 71st Street, New York City, NY 10021, USA. Electronic address:

Background/context: Degenerative lumbar spondylolisthesis (DLS) is a prevalent spinal condition that can result in significant disability. DLS is thought to result from a combination of disc and facet joint degeneration, as well as various biological, biomechanical, and behavioral factors. One hypothesis is the progressive degeneration of segmental stabilizers, notably the paraspinal muscles, contributes to a vicious cycle of increasing slippage.

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