3 results match your criteria: "Ludwig Maximilians Universität[Affiliation]"

Histone variants play a crucial role in chromatin structure organization and gene expression. Trypanosomatids have an unusual H2B variant (H2B.V) that is known to dimerize with the variant H2A.

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Objectives: A video-assisted thoracoscopic surgery (VATS) is an accepted alternative to open thoracotomy (OT) in lung cancer patients undergoing lobectomy, but evidence of the benefits of VATS remains inconsistent. The aim of this study was to compare VATS and OT regarding survival, costs and length of hospital stay (LOS).

Methods: We identified lung cancer patients (incident 2013) undergoing VATS or OT from German insurance claims data and performed 1:2 propensity score matching.

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Nucleophilic reactivities of imide and amide anions.

J Org Chem

August 2010

Department Chemie, Ludwig-Maximilians-Universitäät, Butenandtstrasse 5-13, 81377 München, Germany.

Article Synopsis
  • The study investigated the reaction kinetics of amide and imide anions with benzhydrylium ions and quinone methides using UV-vis spectroscopy in DMSO and acetonitrile.
  • The results revealed a linear correlation between the second-order rate constants and the electrophilicity parameters, enabling the determination of nucleophilicity parameters for these anions.
  • It was found that amide and imide anions are less reactive than similar carbanions due to the lack of resonance stabilization, and the traditional understanding of amide anions' reactivity needs to be updated, as they are primarily attacked at nitrogen.
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