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Clinical significance of brain natriuretic peptide in primary pulmonary hypertension.

J Am Coll Cardiol

March 2004

Division of Pulmonary Diseases, Department of Internal Medicine I, Ludwig Maximilains University, Klinikum Grosshadern, Munich, Germany.

Objectives: The aim of this study was to investigate the potential role of brain natriuretic peptide (BNP) levels in the assessment of functional status and right heart performance in primary pulmonary hypertension (PPH).

Background: Primary pulmonary hypertension is a progressive disease leading to right heart failure and death. Right heart catheterization and maximal or submaximal exercise tests are employed to assess the course of the disease and the effect of therapeutic interventions.

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