Conventional versus task-based package organization for out-of-hospital emergency kits: an emergency medical services simulation study.

Background: Emergency Medical Service crews are equipped with comprehensive emergency kits for routine care and to provide life-saving interventions in severely ill patients. While guidelines on contents and packing strategies of emergency kits for specific tasks and specialized situations exist, data for the design of out-of-hospital emergency kits in a general urban population is lacking. It may be possible to transfer the promising results of modern in-hospital packing strategies such as task-based package organization (TPO) to an Emergency Medical Service setting.

Efficiency and safety of cannabinoid medical use: an analysis of discussions and observed trends on Instagram.

Background: Cannabis and its derivatives show encouraging therapeutic effects in the treatment of various diseases. However, further studies are needed to better assess their efficacy and safety. A promising base for research in the field of medicine and additional pharmacovigilance is social networks, in which experience and knowledge are exchanged between researchers, doctors, and patients, as well as information about the potential risks and benefits of using drugs for medical purposes is disseminated.

Predictive equations in determining resting energy expenditure in patients with head and neck cancer receiving home enteral nutrition.

Objective: It is important to cover energy targets among patients with head and neck cancer (HNC) to minimize weight and skeletal muscles loss. This study aimed to assess the agreement between indirect calorimetry (IC) and predictive equations for determining resting energy expenditures (REE) in HNC patients receiving home enteral nutrition (HEN).

Research Methods And Procedures: Patients included in the study had to be diagnosed with HNC, be adults, have artificial access to the digestive tract, and participate in HEN.

Development and testing of a remote hybrid SMS/web-based perioperative messenger: A mixed-methods study.

Background: Perioperative messengers as tools for hospitals to communicate with patients' loved ones during surgery have been described in form of pagers, SMS, email, and apps. The approach of combining multiple means of communication to create a secure and reliable messenger promises several advantages and has not been investigated to date.

Objective: The aim was to develop and test the technical feasibility and acceptance of a remote hybrid SMS/web-based perioperative messenger that keeps patients' loved ones informed around the time of surgery.

Is global health truly global? A hashtag analysis of #GlobalHealth disparities on X.

Background: X (Formerly known as Twitter) healthcare hashtags are a popular healthcare informatics and educational tool among medical professionals. #Globalhealth is one such widely used hashtag with extensive engagement. This study analyses #GlobalHealth to understand its pattern, global digital distribution, and other parameters during the COVID-19 pandemic on X.

Association Between Anaesthesiologists' Sex and Anaesthesiology Quality Metrics and Postoperative Outcomes: A Retrospective Analysis.

Evidence suggests differences in medical practice and patient outcomes between male and female physicians and surgeons. To date, no such relationships were investigated in anaesthesiologists. This study aimed to investigate an association between anaesthesiologists' sex and anaesthesia quality metrics as well as outcomes.

Optimising co-design processes in telemedicine innovation-developing a telemedical solution for emergency medical services.

Background: Stakeholder engagement plays a vital role in driving advancements in product development. This imperative now extends to the healthcare domain, driven by the scarcity of healthcare professionals and the pressing demand for effective solutions. Through the application of design thinking and co-design methodologies, this study endeavours to promote comprehensive stakeholder involvement, creating streamlined processes and adaptable templates geared towards fostering innovative solutions for tele-emergency medicine.

Bioactive Potential of Algae and Algae-Derived Compounds: Focus on Anti-Inflammatory, Antimicrobial, and Antioxidant Effects.

Algae, both micro- and macroalgae, are recognized for their rich repository of bioactive compounds with potential therapeutic applications. These marine organisms produce a variety of secondary metabolites that exhibit significant anti-inflammatory, antioxidant, and antimicrobial properties, offering promising avenues for the development of new drugs and nutraceuticals. Algae-derived compounds, including polyphenols, carotenoids, lipids, and polysaccharides, have demonstrated efficacy in modulating key inflammatory pathways, reducing oxidative stress, and inhibiting microbial growth.

Effect of chokeberry pomace as a feed additive for high-producing dairy goats on oxidative stress parameters and quality of milk.

Introduction: Chokeberry pomace, rich in polyphenolic compounds, holds potential to be a valuable feed additive for enhancing the antioxidative capacity and overall quality of milk. This study explores the impact of dietary inclusion of chokeberry pomace on oxidative stress parameters and other milk quality parameters in high-producing dairy goats.

Material And Methods: Twenty-seven goats were allocated into three groups: a control group provided standard feed and two experimental groups provided feed supplemented with 15 g or 30 g of chokeberry pomace per kilogram.

Expectations of healthcare professionals of community-based telemedicine in emergency medical service.

Background: In times of demographic change and an immense shortage of qualified personnel in emergency medical services, telemedicine could offer more efficient solutions for better care. Given the community-based nature of emergency services, local communities play an important role. This study explored the expectations of healthcare professionals and volunteers for telemedicine tools in prehospital emergency medicine.

Development and external validation of temporal fusion transformer models for continuous intraoperative blood pressure forecasting.

Background: During surgery, intraoperative hypotension is associated with postoperative morbidity and should therefore be avoided. Predicting the occurrence of hypotension in advance may allow timely interventions to prevent hypotension. Previous prediction models mostly use high-resolution waveform data, which is often not available.

Evaluation of a Video-Based Concept for Hand Hygiene Education of Parents in a Neonatal Intensive Care Unit.

Background: Current clinical guidelines support family-centered care in Neonatal Intensive Care Units (NICUs). This implies parents should also be involved in the most critical patient safety measures. Hand hygiene is the single most important tool to prevent healthcare-associated infections and related long-term effects.

Effects of Ginger () on the Hallmarks of Aging.

Ginger ( Roscoe) is broadly used as a traditional remedy and food ingredient, and numerous preclinical and clinical studies have demonstrated health benefits in a range of age-related disorders. Moreover, longevity-promoting effects have been demonstrated in several (preclinical) research models. With this work, we aimed to comprehensively review the reported effects of ginger and its bioactive constituents on the twelve established hallmarks of aging, with the ultimate goal of gaining a deeper understanding of the potential for future interventions in the area of longevity-extension and counteracting of aging-related diseases.

Using Copy Number Variation Data and Neural Networks to Predict Cancer Metastasis Origin Achieves High Area under the Curve Value with a Trade-Off in Precision.

The accurate identification of the primary tumor origin in metastatic cancer cases is crucial for guiding treatment decisions and improving patient outcomes. Copy number alterations (CNAs) and copy number variation (CNV) have emerged as valuable genomic markers for predicting the origin of metastases. However, current models that predict cancer type based on CNV or CNA suffer from low AUC values.

The Current Landscape of Hypotheses Describing the Contribution of CD4+ Heterogeneous Populations to ALS.

Amyotrophic Lateral Sclerosis (ALS) is a poorly understood and fatal disease. It has a low prevalence and a 2-4 year survival period. Various theories and hypotheses relating to its development process have been proposed, albeit with no breakthrough in its treatment.

Melatonin supplementation counteracts fiber loss in knee ligaments of diabetes-induced rats.

Diabetes mellitus (DM) is a prevalent metabolic disease. The clinical impact of sustained hyperglycemia on ligament healing has not been well characterized. Diabetes is a known cause of macro-, microvascular, and diabetic ulcer healing difficulties among tissues.

Discovery of Curcuminoids as Pancreatic Lipase Inhibitors from Medicine-and-Food Homology Plants.

Researchers are increasingly interested in discovering new pancreatic lipase inhibitors as anti-obesity ingredients. Medicine-and-food homology plants contain a diverse set of natural bioactive compounds with promising development potential. This study screened and identified potent pancreatic lipase inhibitors from 20 commonly consumed medicine-and-food homology plants using affinity ultrafiltration combined with spectroscopy and docking simulations.

A retrospective analysis of the need for on-site emergency physician presence and mission characteristics of a rural ground-based emergency medical service.

Background: This study aimed to address the challenges faced by rural emergency medical services in Europe, due to an increasing number of missions and limited human resources. The primary objective was to determine the necessity of having an on-site emergency physician (EP), while the secondary objectives included analyzing the characteristics of rural EP missions.

Methods: A retrospective study was conducted, examining rural EP missions carried out between January 1st, 2017, and December 2nd, 2021 in Burgenland, Austria.

The Clinical Research on Ginger (Zingiber officinale): Insights from ClinicalTrials.gov analysis.

Ginger () has a rich history of traditional medicinal use and has attracted a global interest in its health benefits. This study aims to provide insights into the clinical research landscape on ginger, focusing on its pharmacological effects and studied health-related outcomes. The study design involves systematic analysis of data from clinical trials available on ClinicalTrials.