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The hippocampi of children with chromosome 22q11.2 deletion syndrome have localized anterior alterations that predict severity of anxiety.

J Psychiatry Neurosci

April 2016

From the Department of Neurology, University of California, Davis (Scott); Department of Psychiatry and Behavioral Sciences, MIND Institute, University of California, Davis (Goodrich-Hunsaker, Kalish, Lee, Hunsaker, Schumann, Simon); and Pennington Biomedical Research Center, Louisiana State University (Carmichael).

Background: Individuals with 22q11.2 deletion syndrome (22q11.2DS) have an elevated risk for schizophrenia, which increases with history of childhood anxiety.

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