5 results match your criteria: "Louis Pasteur Clinic[Affiliation]"
Monomorphic epitheliotropic intestinal T-cell lymphoma comprises morphologic and genomic heterogeneity impacting outcome.
Haematologica
January 2023
Institute of Pathology, Department of Laboratory Medicine and Pathology, Lausanne University Hospital and Lausanne University, Lausanne.
Article Synopsis
- Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is an aggressive, rare form of T-cell lymphoma mainly found in Asia, with a clinical study conducted on 71 European patients showing a median age of 67 years.
- Most patients had gastrointestinal symptoms requiring emergency surgery, with around 40% diagnosed at stage IV, and tumors were classified into typical and atypical morphologies sharing similar immunophenotypic profiles.
- The study highlighted significant genetic alterations, including mutations in genes like MYC, STAT5B, and TP53, which are associated with poor survival outcomes and treatment resistance, indicating the high clinical risk of MEITL.
Background: Occupational stress is a psychosocial risk in the workplace. Working conditions in industrial settings may lead to occupational stress. In Benin, however, there is little epidemiological data on occupational stress in industrial settings.
View Article and Find Full Text PDFMinimizing the risk of contrast-induced nephropathy and hemodynamic collapse during chronic total occlusion percutaneous coronary intervention with a percutaneous left ventricular assist device.
Cardiovasc Revasc Med
September 2018
Interventional Cardiology Unit, Cardio-Thoracic-Vascular Department, San Raffaele Scientific Institute, Milan, Italy. Electronic address:
Candidates for percutaneous coronary revascularization are becoming progressively older and more complex. A combination of factors related to the patient, lesion, and/or hemodynamic conditions may increase the risk of adverse events. Therefore, when a high-risk procedure is identified, it is crucial to provide the patient with adequate support in order to safely perform percutaneous coronary intervention (PCI).
View Article and Find Full Text PDFStem cells as a new treatment for peripheral artery disease: hype or hope? The point of view of a vascular surgeon.
Biomed Mater Eng
September 2015
Pôle Vaisseaux Vascular Center, Laxou, France Louis Pasteur Clinic, Essey-lès-Nancy, France.
Because many of patients with peripheral arterial disease are not eligible for direct or conventional revascularization procedures, because stem cell therapy is being investigated as to its possible role in the treatment of limb ischemia, there is a need to evaluate this treatment and his true application. On the basis of experimental data, preliminary clinical studies have established the safety and feasibility of stem cells implantation in case of critical limb ischemia. Forthcoming large studies, especially randomized placebo controlled double blind studies, related to the optimal cell type, dosage, administration route, will consolidate this evidence and establish mid and long term effectiveness.
View Article and Find Full Text PDFNew trends in vascular surgery.
Biomed Mater Eng
November 2012
Department of Vascular Surgery, Louis Pasteur Clinic, Essey les Nancy, France.
Since the beginning of the 21st century, changes in the western population as the possibility of using endovascular techniques have modified the indications and the operative techniques in all areas of vascular surgery. The classical bypass surgery, which required arterial substitutes, is now less and less used.So, the goal of the arterial research should not be centered on the search of the ideal substitute, but on improving minimally invasive techniques, as cell therapy and regenerative medicine.
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