The role of visfatin in peripheral immune organs and intestines of weaned piglets under lipopolysaccharide induced immune stress.

To investigate the regulatory mechanisms and pathways of visfatin under immune stress injury in weaned piglets, we established a lipopolysaccharide-induced immune stress model in weaned piglets to study how visfatin affects peripheral immune organs and intestinal function. The results revealed that visfatin improved the inflammatory response in immune-stressed weaned piglets by reducing the levels of pro-inflammatory cytokines interleukin-1β, interleukin-6 and monocyte chemoattractant protein-1, as well as decreasing the neutrophil/lymphocyte ratio. Visfatin ameliorated oxidative stress in piglets by promoting the expression of superoxide dismutase and glutathione peroxidase.

Effects of mind-body exercise in children with cerebral palsy-A systematic review and meta-analysis.

Background And Purpose: An increasing number of studies have investigated the efficacy of mind-body exercise in the treatment of children with cerebral palsy (CP). However, the findings of these researches have produced inconsistent results. The objective of this study was to evaluate the effects of mind-body exercise on children with CP in order to provide more conclusive results.

Inhibitory Effect of Puerarin on Lipopolysaccharide-triggered Inflammatory Responses of Bovine Kidney Cells.

Puerarin (Pue), a flavonoid compound, possesses cytoprotective effects and LPS has been reported to induce renal inflammatory injury in bovine. However, whether Pue inhibits lipopolysaccharide (LPS)-induced inflammatory damage of bovine kidney cells remains unknown. Based on an in vitro model with Madin-Darby bovine kidney (MDBK) cell line, it has found that Pue attenuated LPS-induced damage of MDBK cells, as evidenced by cell viability and lactic dehydrogenase (LDH) release rescued by Pue (P < 0.

Cerebrospinal fluid drainage and chronic hydrocephalus in aneurysmal subarachnoid hemorrhage patients with intraventricular hemorrhage.

Background: Patients with intraventricular hemorrhage (IVH) are at a higher risk of developing hydrocephalus and often require external ventricular drainage or long-term ventriculoperitoneal shunt surgery.

Objective: To investigate whether cerebrospinal fluid drainage in patients with IVH due to aneurysmal subarachnoid hemorrhage (aSAH) reduces the incidence of chronic hydrocephalus.

Method: A retrospective analysis was conducted on patients with aSAH treated at our hospital between January 2020 and December 2022.

Anti-Inflammatory Effects of Allocryptopine via the Target on the CX3CL1-CX3CR1 axis/GNB5/AKT/NF-κB/Apoptosis in Dextran Sulfate-Induced Mice.

Allocryptopine (ALL) is an isoquinoline alkaloid extracted from , which has been claimed to have anti-inflammatory and neuroprotection properties. However, the mechanism by which ALL ameliorates inflammatory bowel disease (IBD) remains unclear. Here, we used network pharmacology and quantitative proteomic approaches to investigate the effect of ALL on IBD pathogenesis.

Realistic Reference for Evaluation of Vehicle Safety Focusing on Pedestrian Head Protection Observed From Kinematic Reconstruction of Real-World Collisions.

Head-to-vehicle contact boundary condition and criteria and corresponding thresholds of head injuries are crucial in evaluation of vehicle safety performance for pedestrian protection, which need a constantly updated understanding of pedestrian head kinematic response and injury risk in real-world collisions. Thus, the purpose of the current study is to investigate the characteristics of pedestrian head-to-vehicle contact boundary condition and pedestrian AIS3+ (Abbreviated Injury Scale) head injury risk as functions of kinematic-based criteria, including HIC (Head Injury Criterion), HIP (Head Impact Power), GAMBIT (Generalized Acceleration Model for Brain Injury Threshold), RIC (Rotational Injury Criterion), and BrIC (Brain Injury Criteria), in real-world collisions. To achieve this, 57 vehicle-to-pedestrian collision cases were employed, and a multi-body modeling approach was applied to reconstruct pedestrian kinematics in these real-world collisions.

Pedestrian dynamic response and injury risk in high speed vehicle crashes.

Purpose: The purpose of the current study is to understand pedestrian kinematics, biomechanical response and injury risk in high speed vehicle crashes.

Methods: Vehicle-to-pedestrian crashes at the impact speeds of 40 km/h (reference set) and 70 km/h (analysis set) were simulated employing FE models of a sedan front and an SUV front together with a pedestrian FE model developed using hollow structures. The predictions from crash simulations of different vehicle types and impact speeds were compared and analyzed.

Principal Component Analysis of the Running Ground Reaction Forces With Different Speeds.

Ground reaction force (GRF) is a key metric in biomechanical research, including parameters of loading rate (LR), first impact peak, second impact peak, and transient between first and second impact peaks in heel strike runners. The GRFs vary over time during stance. This study was aimed to investigate the variances of GRFs in rearfoot striking runners across incremental speeds.

An exploratory investigation of patellofemoral joint loadings during directional lunges in badminton.

Anterior knee pain is a commonly documented musculoskeletal disorder among badminton players. However, current biomechanical studies of badminton lunges mainly report kinetic profiles in the lower extremity with few investigations of in-vivo loadings. The objective of this study was to evaluate tissue loadings in the patellofemoral joint via musculoskeletal modelling and Finite Element simulation.

Predicting pedestrian lower limb fractures in real world vehicle crashes using a detailed human body leg model.

Purpose: The purpose of this study was to evaluate the capability of a detailed FE human body lower limb mode, called HALL (Human Active Lower Limb) model, in predicting real world pedestrian injuries and to investigate injury mechanism of pedestrian lower limb in vehicle collisions.

Methods: Two real world vehicle-to-pedestrian crashes with detailed information were selected. Then, a pedestrian model combining the HALL model and the upper body of the 50th% Chinese dummy model and vehicle front models were developed to reconstruct the selected real world crashes, and the predictions of the simulations were analyzed together with observations from the accident data.

Processing uncertain RFID data in traceability supply chains.

Radio Frequency Identification (RFID) is widely used to track and trace objects in traceability supply chains. However, massive uncertain data produced by RFID readers are not effective and efficient to be used in RFID application systems. Following the analysis of key features of RFID objects, this paper proposes a new framework for effectively and efficiently processing uncertain RFID data, and supporting a variety of queries for tracking and tracing RFID objects.

[Bird species diversity and related protection measures in urban park green spaces of Loudi City, Hunan Province of China].

Urban park green space is an important physical part of urban ecosystem, and also, the important habitat and carrier for birds and other animals. Rapid urbanization induces the great change in the spatial pattern of urban park green space, while the patched distribution of urban park green space has the habitat features similar to 'habitat islands', giving obvious effects on urban avian communities. In order to understand the bird species distribution and species diversity in Loudi City and to provide the basic information for the bird conservation, a line transect method and a quadrat sampling method were adopted to investigate the distribution pattern and species richness of the birds across seven urban parks in the Loudi City from November, 2010 to January, 2012.