15 results match your criteria: "Los Angeles General Hospital[Affiliation]"

Article Synopsis
  • * A meta-analysis of five studies involving 191 patients found DECT to have a sensitivity of 88.1% and specificity of 82% for diagnosing ACL ruptures, showing strong accuracy, particularly for complete ruptures.
  • * The results indicate that DECT can be a reliable option for diagnosing ACL injuries in acute or subacute settings, supporting its use when MRI is not available or appropriate.
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  • - Head and neck cancers rank as the seventh most common worldwide, and lymph node metastasis (LNM) is a key factor that negatively impacts survival; traditional imaging methods struggle with accurate detection of LNM.
  • - This study systematically searched various databases for research on AI models diagnosing LNM in head and neck cancers, finding 23 relevant articles that primarily focused on internal validation due to a lack of external validation.
  • - The analysis showed high diagnostic accuracy for AI models, with pooled AUC scores of 91% for CT-based, 84% for MRI-based, and 92% for PET/CT-based radiomics; further, deep learning models performed similarly well, indicating a need for more extensive multicenter research for
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Article Synopsis
  • Previous studies show that many healthcare providers overestimate the risks of radiation from imaging during pregnancy, leading to a reluctance to perform necessary imaging, even when it could greatly benefit patient care.
  • This study aimed to assess current knowledge and confidence levels regarding imaging pregnant patients among various medical specialists through an anonymous survey, including radiologists and OB/GYN providers.
  • The survey results revealed a general correct response rate of 68.5% across 18 questions, highlighting significant variability in knowledge, with some questions showing low correct response rates and most respondents feeling only "fairly" confident in their imaging decisions.
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3-methylcrotonyl-CoA carboxylase (3-MCC) deficiency is an autosomal recessive disorder of leucine metabolism. Since 3-MCC deficiency is thought to be a benign condition, a few newborn screening programs discontinued to screen this condition. We report a case of a 24-year-old previously healthy male patient who developed generalized rhabdomyolysis, weakness, respiratory and renal failure, acute pancreatitis, hyperammonemia, and altered consciousness after strenuous exercise.

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Interpretive artificial intelligence (AI) tools are poised to change the future of radiology. However, certain pitfalls may pose particular challenges for optimal AI interpretative performance. These include anatomic variants, age-related changes, postoperative changes, medical devices, image artifacts, lack of integration of prior and concurrent imaging examinations and clinical information, and the satisfaction-of-search effect.

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Hearing loss is frequently associated with Gaucher disease (GD). Gaucher cells are enlarged reticuloendothelial cells containing glucocerebroside in the lysosomes due to deficiency of the glucocerebrosidase. Gaucheromas consist of accumulated Gaucher cells.

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De novo variants in immune regulatory genes in Down syndrome regression disorder.

J Neurol

August 2024

Division of Neurology, Department of Pediatrics, Children's Hospital Los Angeles, 4650 Sunset Blvd, Mailstop 82, Los Angeles, CA, 90027, USA.

Background: Down Syndrome Regression Disorder (DSRD) is a rare and poorly understood disorder of the central nervous system, characterized by acute or subacute neuropsychiatric symptoms in previously healthy individuals with Down syndrome (DS). Many patients exhibit immunotherapy-responsiveness, indicative of immune dysregulation as a potential underlying etiology. While hypotheses are emerging regarding the role of interferon signaling in DSRD and other autoimmune conditions associated with DS, it is unclear why a small subset of individuals with DS develop DSRD.

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Safety net systems care for patients with a high burden of liver disease yet experience many barriers to liver transplant (LT) referral. This study aimed to assess safety net providers' perspectives on barriers to LT referrals in the United States. We conducted a nationwide anonymous online survey of self-identified safety net gastroenterologists and hepatologists from March through November 2022.

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Grill-Related Burn Injuries: A Matched Cohort Study.

J Burn Care Res

May 2024

Division of Plastic and Reconstructive Surgery, University of Southern California, Los Angeles, CA 90033, USA.

Barbequing can result in devastating burn injuries with unsafe practices. This study aims to characterize the demographics, injury characteristics, and outcomes of grill-related burns and identify ways of burn prevention. A retrospective review of patients admitted to a single-institution, metropolitan burn center from January 1, 2017, to July 1, 2023.

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