7 results match your criteria: "Longgang Otorhinolaryngology Hospital of Shenzhen[Affiliation]"

Backgound: Preformed metal crowns (PMCs) and zirconia crowns (ZCs) are commonly used for the treatment of primary molar caries. However, there have been no reports on factors influencing parental awareness, willingness to use these treatments, and the associated discomfort after crown placement in children.This study is the first to report factors influencing preformed crowns, providing a reference for the prevention and treatment of deciduous carious teeth.

View Article and Find Full Text PDF

LL-37 regulates odontogenic differentiation of dental pulp stem cells in an inflammatory microenvironment.

Stem Cell Res Ther

December 2024

Key Lab. of Oral Diseases Research, College and Hospital of Stomatology, Anhui Medical University, Hefei, 230032, Anhui Province, China.

Background: Inflammation often causes irreversible damage to dental pulp tissue. Dental pulp stem cells (DPSCs), which have multidirectional differentiation ability, play critical roles in the repair and regeneration of pulp tissue. However, the presence of proinflammatory factors can affect DPSCs proliferation, differentiation, migration, and other functions.

View Article and Find Full Text PDF

Enamel adhesion is acknowledged as durable; however, achieving long-lasting dentin adhesion remains a formidable challenge due to degradation of exposed collagen matrix after acid-etching of dentin. The idea of developing an enamel-like adhesion interface holds great promise in achieving enduring dentin adhesion. In this study, we constructed an enamel-like adhesion interface using a rapid remineralization strategy comprising an acidic primer and a rapid remineralization medium.

View Article and Find Full Text PDF

Biomimetic mineralization of collagen from fish scale to construct a functionally gradient lamellar bone-like structure for guided bone regeneration.

Int J Biol Macromol

November 2024

Key Lab. of Oral Diseases Research of Anhui Province, College & Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China; The Institute of Oral Science, Department of Stomatology, Longgang Otorhinolaryngology Hospital of Shenzhen, Shenzhen 518172, China. Electronic address:

Article Synopsis
  • The study addresses challenges in guided bone regeneration (GBR) membranes, focusing on integrating mechanical properties with degradation rates to treat critical bone defects.
  • Researchers developed a new GBR membrane inspired by fish scales, using epigallocatechin gallate and biomimetic mineralization, resulting in a structure similar to natural bone.
  • The newly created membrane demonstrated excellent mechanical and biological properties, promoting bone repair and regeneration in both laboratory cell cultures and animal models, showcasing its potential for clinical applications.
View Article and Find Full Text PDF

Extrafibrillar demineralization: Yes or no?

Dent Mater

August 2024

Department of Stomatology, The First Affiliated Hospital of Anhui Medical University, 218 Jixilu Rd., Hefei 230032, China; Key Lab. of Oral Diseases Research of Anhui Province, College & Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China; Department of Stomatology. Longgang Otorhinolaryngology Hospital of Shenzhen, No. 3004L Longgang Avenue, 518172, China. Electronic address:

Objective: Extrafibrillar demineralization is considered to be an ideal solution for addressing the durability of resin-dentin bonding interfaces. However, its theoretical basis is contradictory to ionization equilibrium of hydroxyapatite dissolution. In this study, various calcium chelators were selected as dentin conditioners to explore the essence of dentin demineralization with chelators and its effect on resin-dentin adhesion.

View Article and Find Full Text PDF

Bottom-Up Assembling Hierarchical Enamel-Like Bulk Materials with Excellent Optical and Mechanical Properties for Tooth Restoration.

Adv Healthc Mater

October 2024

Key Laboratory of Oral Diseases Research of Anhui Province, College & Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei, 230032, China.

Enamel has good optical and mechanical properties because of its multiscale hierarchical structure. Biomimetic construction of enamel-like 3D bulk materials at nano-, micro-, mesh- and macro-levels is a challenge. A novel facile, cost-effective, and easy large-scale bottom-up assembly strategy to align 1D hydroxyapatite (HA) nanowires bundles to 3D hierarchical enamel structure with the nanowires bundles layer-by-layer interweaving orientation, is reported.

View Article and Find Full Text PDF

Colloidal Phenol-Amine Coating on Implants for Improved Anti-Inflammation and Osteogenesis.

ACS Biomater Sci Eng

January 2024

Key Lab. of Oral Diseases Research of Anhui Province, College & Hospital of Stomatology, Anhui Medical University, 81 Meishan Road, Hefei 230032, China.

Phenol-amine coatings have attracted significant attention in recent years owing to their adjustable composition and multifaceted biological functionalities. The current preparation of phenol-amine coatings, however, involves a chemical reaction within the solution or interface, resulting in lengthy preparation times and necessitating specific reaction conditions, such as alkaline environments and oxygen presence. The facile, rapid, and eco-friendly preparation of phenol-amine coatings under mild conditions continues to pose a challenge.

View Article and Find Full Text PDF