146 results match your criteria: "LongDong University[Affiliation]"

Recently, the role of competing endogenous RNAs in regulating gene expression through the interaction of microRNAs has been closely associated with the expression of circular RNAs (circRNAs) in various biological processes such as reproduction and apoptosis. While the number of confirmed circRNA-miRNA interactions (CMIs) continues to increase, the conventional in vitro approaches for discovery are expensive, labor intensive, and time consuming. Therefore, there is an urgent need for effective prediction of potential CMIs through appropriate data modeling and prediction based on known information.

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BCMCMI: A Fusion Model for Predicting circRNA-miRNA Interactions Combining Semantic and Meta-path.

J Chem Inf Model

August 2023

Guangxi Key Lab of Human-Machine Interaction and Intelligent Decision, Guangxi Academy of Sciences, Nanning, Guangxi 530007, China.

More and more evidence suggests that circRNA plays a vital role in generating and treating diseases by interacting with miRNA. Therefore, accurate prediction of potential circRNA-miRNA interaction (CMI) has become urgent. However, traditional wet experiments are time-consuming and costly, and the results will be affected by objective factors.

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Coal seam gas pressure is an important index to evaluate the risk of coal outbursts. The accuracy of measurement is closely related to the quality of hole sealing, and reasonable grouting pressure is one of the key factors to determine the quality of hole sealing. To obtain a reasonable grouting pressure, a mathematical model for slurry flow was established based on the relationship between the seepage law of the slurry and the properties of the borehole surrounding a rock.

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A high-quality genome assembly highlights the evolutionary history of the great bustard (Otis tarda, Otidiformes).

Commun Biol

July 2023

MOE Key Laboratory of Freshwater Fish Reproduction and Development, Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing, 400715, China.

Conservation genomics often relies on non-invasive methods to obtain DNA fragments which limit the power of multi-omic analyses for threatened species. Here, we report multi-omic analyses based on a well-preserved great bustard individual (Otis tarda, Otidiformes) that was found dead in the mountainous region in Gansu, China. We generate a near-complete genome assembly containing only 18 gaps scattering in 8 out of the 40 assembled chromosomes.

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Benzoate-based thermally activated delayed fluorescence materials.

RSC Adv

July 2023

Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences Beijing 100190 China

Compounds PTZ-MBZ (methyl 3-(10-phenothiazin-10-yl)benzoate) and DMAC-MBZ (methyl 3-(9,9-dimethylacridin-10(9)-yl)benzoate) were conveniently synthesized, and they exhibited TADF properties with lifetimes of 0.80 and 2.17 μs, respectively.

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A novel strategy for quantification of α2,3- and α2,6-linked sialic acids in sialylated glycoproteins.

Carbohydr Res

September 2023

Laboratory for Functional Glycomics, College of Life Sciences, Northwest University, Xi'an, Shaanxi, China.

Sialic acid, a monosaccharide containing nine carbon atoms, is widely distributed in eukaryotic cells. The bound sialic acids are mainly present at the glycan ends of glycoconjugates via α2-3 or α2-6 glycosidic bonds, and alterations in their expression levels and linkage types are associated with the progress of many diseases and tumors. The present study provides a new strategy for quantification of α2,3- and α2,6-linked sialic acids in sialylated glycoproteins.

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Objective: This study aims to investigate the CT-DNA (Calf thymus DNA) binding properties and HeLa cell viabilities of metal complexes derived from (E)-2-hydroxy-N'-((thiophen-2-yl)methylene)benzohydrazone (H2L1) and (E)-N'-((thiophen-2-yl)methylene)isonicotinylhydrazone (HL2).

Materials And Methods: A series of metal complexes derived from (E)-2-hydroxy-N'-((thiophen-2-yl)methylene)benzohydrazone (H2L1) and (E)-N'-((thiophen-2-yl)methylene)isonicotinylhydrazonewere (HL2) were synthesized, and their structures were characterized through FT-IR, ESI-MS, elemental analysis, molar conductivities and X-ray diffraction. DNA binding properties between CT-DNA and metal complexes were investigated by UV-Vis spectrophotometry and viscosity titration.

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Synthesis and Properties of Short-Lifetime Thermally Activated Delayed Fluorescence Materials.

ACS Omega

June 2023

Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.

Compounds , , , , and were conveniently synthesized, and they were found to exhibit TADF properties with lifetimes of 857, 575, 561, 768, and 600 ns, respectively. These short lifetimes of the compounds might be due to the combination of small singlet-triplet splitting energy (Δ) and benzoate group, which could be an efficient strategy for the further design of short-lifetime TADF materials.

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Metabolome and transcriptome signatures shed light on the anti-obesity effect of .

Front Plant Sci

April 2023

State Key Laboratory of Crop Stress Adaptation and Improvement, Henan Joint International Laboratory for Crop Multi-Omics Research, School of Life Sciences, Henan University, Kaifeng, China.

Obesity has become one of the major threats to human health across the globe. The rhizomes of have shown promising anti-obesity effect. However, the metabolic and genetic basis mediating this beneficial effect are not fully resolved.

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Pillar[5]arene-based supramolecular pseudorotaxane polymer material for ultra-sensitive detection of Fe and F.

RSC Adv

April 2023

Gansu Key Laboratory of Protection and Utilization for Biological Resources and Ecological Restoration, College of Chemistry and Chemical Engineering, Longdong University Qingyang Gansu 745000 P. R. China

Recent advancements in ultra-sensitive detection, particularly the Aggregation Induced Emission (AIE) materials, have demonstrated a promising detection method due to their low cost, real-time detection, and simplicity of operation. Here, coumarin functionalized pillar[5]arene (P5C) and bis-bromohexyl pillar[5]arene (DP5) were successfully combined to create a linear AIE supramolecular pseudorotaxane polymer (PCDP-G). The use of PCDP-G as a supramolecular AIE polymer material for recyclable ultra-sensitive Fe and F detection is an interesting application of the materials.

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The stability of artificial sand-binding vegetation determines the success or failure of restoration of degraded ecosystem, accurately evaluating the stability of artificial sand-binding vegetation can provide evidence for the future management and maintenance of re-vegetated regions. In this paper, a novel data-driven evaluation model was proposed by combining statistical methods and a neural network model to evaluate the stability of artificial sand-binding vegetation in the southeastern margins of the Tengger Desert, where the evaluation indexes were selected from vegetation, soil moisture, and soil. The evaluation results indicate that the stability of the artificially re-vegetated belt established in different years (1956a, 1964a, 1981a, and 1987a) tend to be stable with the increase of sand fixation years, and the artificially re-vegetated belts established in 1956a and 1964a have almost the same stability, but the stability of the artificially re-vegetated belt established in 1981a and 1987a have a significant difference.

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Accurate estimation of evaporation is of great significance for understanding regional drought, and managing and applying limited water resources in dryland. However, the application of the traditional estimation approaches is limited due to the lack of required meteorological parameters or experimental conditions. In this study, a novel hybrid model was proposed to estimate the monthly pan Ep in dryland by integrating long short-term memory (LSTM) with grey wolf optimizer (GWO) algorithm and Kendall-τ correlation coefficient, where the GWO algorithm was employed to find the optimal hyper-parameters of LSTM, and Kendall-τ correlation coefficient was used to determine the input combination of meteorological variables.

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Motivation: A large number of studies have shown that circular RNA (circRNA) affects biological processes by competitively binding miRNA, providing a new perspective for the diagnosis, and treatment of human diseases. Therefore, exploring the potential circRNA-miRNA interactions (CMIs) is an important and urgent task at present. Although some computational methods have been tried, their performance is limited by the incompleteness of feature extraction in sparse networks and the low computational efficiency of lengthy data.

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Introduction: Student engagement is a best predictor variable of student' development and success. It can be highly influenced by internal and external environmental factors, such as perceived teacher support.

Methods: In order to explore the influence of perceived teacher support on student engagement among higher vocational students, this study conducted a questionnaire on 1,136 Chinese higher vocational students using perceived teacher support, basic psychological needs satisfaction, learning drive, student engagement and Optimistic attributional styles for explaining positive events (OAS_P) five scales.

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Evolutionary analysis of a complete chicken genome.

Proc Natl Acad Sci U S A

February 2023

Integrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Key Laboratory of Freshwater Fish Reproduction and Development (Ministry of Education), Key Laboratory of Aquatic Science of Chongqing, School of Life Sciences, Southwest University, Chongqing 400715, China.

Microchromosomes are prevalent in nonmammalian vertebrates [P. D. Waters , (2021)], but a few of them are missing in bird genome assemblies.

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Background: S100 calcium-binding protein A9 (S100A9) is a commonly known pro-inflammatory factor involved in various inflammatory responses. ( ) type C is known to cause diarrhea in piglets. However, the role of in C-induced infectious diarrhea is unclear.

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Background: Long non-coding RNAs (lncRNAs), as key regulators, are closely associated with the development of a variety of disease. However, the mechanisms by which lncRNAs regulate type C induced piglet diarrhea are unclear.

Methods: In the present study, we explored the expression and characterization of lncRNAs in a beta2 (CPB2) toxin-treated intestinal porcine epithelial cell line-J2 (IPEC-J2) using RNA-sequencing (RNA-seq).

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MFIDMA: A Multiple Information Integration Model for the Prediction of Drug-miRNA Associations.

Biology (Basel)

December 2022

Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi'an 710129, China.

Abnormal microRNA (miRNA) functions play significant roles in various pathological processes. Thus, predicting drug-miRNA associations (DMA) may hold great promise for identifying the potential targets of drugs. However, discovering the associations between drugs and miRNAs through wet experiments is time-consuming and laborious.

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Background: As an important regulator of autoimmune responses and inflammation, S100A9 may serve as a therapeutic target in inflammatory diseases. However, the role of S100A9 in Clostridium perfringens type C infectious diarrhea is poorly studied. The aim of our study was to screen downstream target genes regulated by S100A9 in Clostridium perfringens beta2 (CPB2) toxin-induced IPEC-J2 cell injury.

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It is a great challenge to design and prepare polymeric membranes with excellent permeability and good rejection. In this study, a modifier of gold nanoparticles for crosslinking and self-assembly by 1,6-hexanedithiol is fabricated and used to modify the polyethersulfone membrane as an additive, which forms a uniform porous membrane by liquid-liquid phase conversion technology. The morphology of the membrane is investigated by scanning electron microscopy (SEM), the change of the hydrophilicity of the membrane surface after modification is measured by the contact angle goniometer, and the performance of the fabricated membrane is measured by evaluating the pure water flux and the rejection ratio of bovine serum albumin.

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[Detection and Characteristics of Hepatitis C Virus Infection among Blood Donors in Qingyang City].

Zhongguo Shi Yan Xue Ye Xue Za Zhi

December 2022

Provincial Key Laboratory for Protection and Utilization of Longdong Bio-resources in Gansu Province, Longdong University, Qingyang 745000, Gansu Province, China.

Article Synopsis
  • The study aimed to assess the prevalence of hepatitis C virus (HCV) among blood donors in Qingyang City to mitigate transmission risks.
  • It found a 3.2‰ positive rate of HCV among donors from 2015 to 2020, with the most common co-infection being with treponema pallidum, and had a higher prevalence in males and married individuals.
  • The research highlighted a need for better HCV awareness among young blood donors, who scored a 67.2% knowledge rate about the virus.
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The sustainability of artificial sand-binding vegetation is determined by the water balance between evapotranspiration (ET) and precipitation in desert regions. Consequently, accurately estimating ET is a critical prerequisite for determing the types and spatial distribution of artificial vegetation in different sandy areas. For this purpose, a novel hybrid estimation model was proposed to estimate monthly ET by coupling the deep learning long short term memory (LSTM) with variational mode decomposition (VMD) and whale optimization algorithm (WOA) (i.

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Metabolomic Analysis of Wheat Grains after Kühn Infection by Using Ultrahigh-Performance Liquid Chromatography-Q-Exactive Mass Spectrometry.

Metabolites

August 2022

State Key Laboratory for Biology of Plant Disease and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

causes common bunt disease in wheat, with severe losses of production yield and seed quality. Metabolomics studies provide detailed information about the biochemical changes at the cell and tissue level of the plants. Ultrahigh-performance liquid chromatography-Q-exactive mass spectrometry (UPLC-QE-MS) was used to examine the changes in wheat grains after infection.

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Environmental factors are the major constraints in sustainable agriculture. WRKY proteins are a large family of transcription factors (TFs) that regulate various developmental processes and stress responses in plants, including cotton. On the basis of genome sequencing, WRKY TFs have been identified in cotton and characterized for their functions in abiotic stress responses.

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The transesterification of lecithin with methanol catalyzed by 23 kinds of alkaline salts was investigated for the preparation of biodiesel. Sodium carbonate was confirmed as the best catalyst due to its excellent catalytic performance, environmental friendliness, and great stability. Next, it was successfully immobilized on the surface of hierarchical nanosheets of MoS.

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