794 results match your criteria: "Londrina State University.[Affiliation]"

Probiotic vegetable-based beverages, such as lychee, can be rich in nutrients, free of cholesterol and lactose, and also have few allergenic components. is an alternative to make lychee juice a probiotic beverage. This work aimed to develop probiotic lychee beverage (LB) using by evaluating the effect of refrigerated storage on cell viability, physicochemical characteristics, and acceptance.

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Analysis of choroidal markers of activity in pachychoroid disease spectrum.

Graefes Arch Clin Exp Ophthalmol

January 2025

Londrina State University, Avenida Robert Koch, 60, Londrina, CEP 86038-440, Paraná, Brazil.

Purpose: To detect choroidal markers of disease activity in eyes with chronic active unilateral pachychoroid disease spectrum (PDS) compared to the non-active contralateral eyes, based on multimodal imaging and particularly indocyanine green angiography (ICGA).

Methods: An observational retrospective case-control study. The study evaluated individuals diagnosed with chronic active unilateral PDS (group 1) by comparing the eyes with the non-active fellow eyes (group 2).

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Background: Physical activity, sedentary behaviour, and diet synergically coexist (in different ways) within adolescents' lifestyles. Thus, understanding obesogenic behaviour patterns within populations is critical to promoting adolescents' health. This study investigates clustering patterns of adolescents' obesogenic behaviours across South American countries.

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Objective: To evaluate the influence of in situ acid erosion on the structural and optical properties of nanoparticulate bisacrylic resin with different surface treatments, evaluating surface roughness (Ra), knoop microhardness (KHN), color change (ΔE, ΔL, ΔC, ΔH), contrast (CR) and translucency (TP).

Methods: Eighty specimens were made (n = 10 per group) and the following surface treatments were applied: U-unpolished; A-polishing with Astropol rubber tips (Ivoclar); S-Biscover LV surface sealant (Bisco) and S-Palaseal surface sealant (kulzer). For the in situ experiment, 10 volunteers wore an intraoral appliance containing eight specimens (two specimens per experimental group), with only one specimen from each experimental group being subjected to the acid process.

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We compared performing preacher and incline biceps curls on changes in elbow flexors muscle size and strength. This was a between-group repeated measures randomized trial. Sixty-three young women performed preacher biceps curl (PC, n = 30) or incline biceps curl (IC, n = 33) for 8 weeks, twice a week.

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This review explores recent technological advances in intraoperative imaging during retinal disease surgeries, focusing on their applicability in clinical practice and impact on surgical outcomes. A literature search identified studies discussing new imaging technologies, their advantages over conventional methods, relevant case studies, and literature reviews. Exclusion criteria included studies unrelated to retinal diseases, imaging technologies not suitable for intraoperative use, outdated articles, and nonscientific reports.

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Nitric oxide (NO) is a multifunctional signaling molecule in plants, playing key roles in germination, microbial symbiosis, and nodule formation. However, its instability requires innovative approaches, such as using nanoencapsulated NO donors, to prolong its effects. This study evaluated the impact of treating soybean () seeds with the NO donor S-nitrosoglutathione (GSNO), encapsulated in polymeric nanoparticles, on the germination, nodulation, and plant growth.

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Neuropathy is the most common complication of diabetes, leading to painful symptoms like hyperalgesia. Current treatments for diabetic painful neuropathy often prove inadequate, necessitating the exploration of new pharmacological approaches. Therefore, this study aimed to investigate the potential antinociceptive effect of aspirin-triggered lipoxin A4 (ATL), a specialized pro-resolving lipid mediator, when administered alone or in combination with cannabinoid agonists, to alleviate diabetic neuropathic pain.

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Article Synopsis
  • Central Serous Chorioretinopathy (CSC) is characterized by retinal detachments due to fluid leakage, often linked to stress, psychiatric issues, or corticosteroid use, prompting a study to investigate BALAD as a potential biomarker for CSC severity.
  • The research involved a global case-control study of patients with CSC, assessing clinical characteristics, risk factors, and OCT findings in those with and without Bacillary Layer Detachment (BALAD) to better understand its implications in diagnosis and treatment.
  • Results showed 37 patients with CSC and BALAD, revealing distinct clinical features on examination and OCT, compared to a control group without BALAD, suggesting significant differences in the manifestation of CSC.
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Betalains are naturally occurring pigments sourced mainly from (beetroot), spp. (dragon fruit), spp., and spp.

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Protective role of TRPV1 nociceptive neurons communication to macrophages against infection in mice.

Brain Behav Immun Health

December 2024

Department of Immunology, Parasitology and General Pathology, Center of Biological Science, State University of Londrina, Rodovia Celso Garcia Cid KM480 PR445, 86051-990, Postal Address 10.011, Londrina, Paraná, Brazil.

Chagas' disease is a life-threatening condition caused by . Patients with chronic disease may develop gastrointestinal, neurological, or associated neuro-digestive dysfunctions. CNS invasion by can occur in the acute phase, and its presence in the brain and cerebrospinal fluid was reported.

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Functional Measures in Non-COPD Chronic Respiratory Diseases: A Systematic Review.

J Clin Med

November 2024

Laboratory of Research in Respiratory Physiotherapy (LFIP), Department of Physiotherapy, Londrina State University (UEL), Londrina 86038-3500, Brazil.

Article Synopsis
  • A systematic review was conducted to evaluate functional performance (FP) instruments for chronic respiratory diseases (CRD) other than chronic obstructive pulmonary disease (COPD), highlighting the challenge of selecting the right tool.
  • The review found and analyzed 216 studies across seven types of CRD, identifying 33 different FP instruments, with the SF-36 questionnaire and the 1-minute sit-to-stand test being the most commonly used.
  • Despite the widespread use of these instruments, there is limited data on their measurement properties and clinical significance, making this review essential for guiding clinical choices in non-COPD CRD.
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Athletes in bodybuilding can pose favouring one side or the other of the body while being evaluated in the contests. While previous research assessed lateral bias of posing in a variety of situations, no investigation has been conducted in bodybuilding. We analyzed the lateral posing bias of the Top 15 athletes for the mandatory poses in Classic Physique Mr.

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This study evaluated the effects of oral pentoxifylline on testicular biometry, histology, and gene expression in stallions subjected to scrotal heat stress. Fourteen stallions were divided into three groups: Control (CRL, n = 4), Testicular Degeneration (DEG, n = 5), and Testicular Degeneration Treated with Pentoxifylline (DEG + PTX, n = 5). Testicular degeneration was induced by scrotal insulation, twice daily, over two consecutive days (D-1 and D0).

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Vascular hamartoma is an abnormal development of endothelial tissue that rarely affects horses. Histopathological examination remains the gold standard for definitive diagnosis, yet the presence of abnormal vascular structures must be carefully differentiated from other vascular anomalies and neoplasms. This report describes two cases of vascular proliferation affecting the skin on the lateral side over the left tarsus and the dorsolateral region over the fetlock joint of two fillies.

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Introduction And Hypotheses: Few studies have investigated the relationship between work productivity (WP) and overactive bladder syndrome (OABS). The majority of those that do use generic productivity questionnaires or only include WP as a secondary outcome. We evaluated the impact of OABS on specific domains of WP, with the hypothesis that OABS has an impact on the domains of efficiency, concentration, vigor, and irritability, lost working hours, interruptions, and impairment to the work schedule.

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Endometriosis is a debilitating and painful gynecological inflammatory disease affecting up to 15% of women and transgender men. Current treatments are ineffective for a substantial proportion of patients, underscoring the need for additional therapies with long-term benefits. Nociceptors release neuropeptides, such as calcitonin gene-related peptide (CGRP), which are known to shape immunity through neuroimmune communication.

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BCL-2 and γ-H2AX immunostaining profile in urothelial bladder cancer prognosis.

Pathol Res Pract

December 2024

Laboratory of Mutagenesis and Oncogenetics, Department of General Biology, Londrina State University, Londrina, PR, Brazil. Electronic address:

Urothelial bladder carcinoma (UBC) is a malignant neoplasm of the urinary tract that is highly prevalent worldwide and has a high rate of tumor recurrence. It is known that the BCL2 apoptosis regulator (BCL-2) gene encodes a mitochondrial protein that regulates programmed death cells by apoptosis. In contrast, the H2A.

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Purpose: The purpose of this study is to analyze the associations between participation in physical education (PE) classes and days with ≥60 minutes of moderate- to vigorous-intensity physical activity (MVPA) using different reference categories for participation in PE.

Methods: We used self-reported data from 284,820 adolescents.

Results: When no participation in PE was the reference, participation on 1 (prevalence ratio [PR] = 1.

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Secular trends and sociodemographic disparities in physical activity among adults in eleven African countries: WHO STEPS 2003-2020.

Int J Behav Nutr Phys Act

October 2024

Center for Epidemiological Research in Nutrition and Health, Department of Nutrition, School of Public Health, Universidade de São Paulo (USP), São Paulo, SP, Brazil.

Background: Mortality from physical inactivity-related non-communicable diseases (NCDs) is projected to surpass deaths from communicable diseases by 2030 in Africa. Monitoring physical activity (PA) is important for planning public health interventions addressing NCDS and planetary health, but there is a dearth of evidence on PA trends in Africa. This study explored the secular trends in overall and domains of PA (leisure, occupation, and transport), and examined the gender, age, and education disparities in PA trends across African countries.

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Landscape transcriptomic analysis of bovine follicular cells during key phases of ovarian follicular development.

Biol Res

October 2024

Department of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Rua Prof. Doutor Walter Mauricio Correa, s/n, Botucatu, São Paulo, 18618-681, Brazil.

Background: There are many gaps in our understanding of the mechanisms involved in ovarian follicular development in cattle, particularly regarding follicular deviation, acquisition of ovulatory capacity, and preovulatory changes. Molecular evaluations of ovarian follicular cells during follicular development in cattle, especially serial transcriptomic analyses across key growth phases, have not been reported. This study aims to address this gap by analyzing gene expression using RNA-seq in granulosa and antral cells recovered from ovarian follicular fluid during critical phases of ovarian follicular development in Holstein cows.

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This study aimed to evaluate the feasibility of performing multiple testicular biopsies in rams using Tru-cut® needles, assessing histological structure, gene expression, and potential complications such as effects on semen quality, testicular blood flow, and ultrasonographic echotexture. In Exp. 1, six mature rams underwent testicular biopsies at intervals (0, 3, 6, 12, 24, and 48 h) using a 16 G Tru-cut® needle, with alternating testes for each collection.

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Article Synopsis
  • The study aimed to explore how psychological distress in early adulthood affects physical activity patterns as people age.
  • Researchers used data from two large studies, assessing psychological distress and self-reported leisure-time physical activity at various ages.
  • Findings revealed that individuals with psychological distress in their early twenties were significantly less likely to maintain high levels of physical activity later in life compared to those without distress.
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Social determinants of health and youth chronic pain.

Complement Ther Clin Pract

November 2024

Department of Physical Education, Shanghai Jiao Tong University, Shanghai, China. Electronic address:

Article Synopsis
  • The study aimed to understand how various social determinants of health (SDOH) relate to chronic pain in children and adolescents in the U.S.
  • Researchers analyzed data from a national sample of 30,287 youth, focusing on five SDOH domains, alongside caregiver self-reports of chronic pain.
  • Findings indicated that factors like food insufficiency, parental unemployment, limited access to quality healthcare, and low school engagement significantly increased the likelihood of chronic pain among these youth.
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Perceptual training enhances the ability to anticipate crucial information for decision-making, for example, a soccer goalkeeper predicting penalty kick direction. However, it remains unclear whether perceptual practice alone (implicit method) is sufficient for optimal decision-making improvement, or whether emphasising pertinent details during practice (explicit method) could yield better results. This study compared implicit and explicit methods of learning ball direction prediction during soccer penalties, involving both goalkeepers and non-soccer players (novices).

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