3 results match your criteria: "Loma Linda Universitygrid.43582.38[Affiliation]"
New Roles for HAMP Domains: the Tri-HAMP Region of Pseudomonas aeruginosa Aer2 Controls Receptor Signaling and Cellular Localization.
J Bacteriol
September 2022
Division of Microbiology and Molecular Genetics, Loma Linda Universitygrid.43582.38, Loma Linda, California, USA.
The Aer2 chemoreceptor from Pseudomonas aeruginosa is an O sensor involved in stress responses, virulence, and tuning the behavior of the chemotaxis (Che) system. Aer2 is the sole receptor of the Che2 system. It is soluble, but membrane associated, and forms complexes at the cell pole during stationary phase.
View Article and Find Full Text PDFLeptospira interrogans Aer2: an Unusual Membrane-Bound PAS-Heme Oxygen Sensor.
J Bacteriol
April 2022
Division of Microbiology and Molecular Genetics, Loma Linda Universitygrid.43582.38, Loma Linda, California, USA.
In this study, we provide the first characterization of a chemoreceptor from Leptospira interrogans, the cause of leptospirosis. This receptor is related to the Aer2 receptors that have been studied in other bacteria. In those organisms, Aer2 is a soluble receptor with one or two PAS-heme domains and signals in response to O binding.
View Article and Find Full Text PDFRole of the Filifactor alocis Hypothetical Protein FA519 in Oxidative Stress Resistance.
Microbiol Spectr
December 2021
Division of Microbiology and Molecular Genetics, Department of Basic Sciences, School of Medicine, Loma Linda Universitygrid.43582.38, Loma Linda, California, USA.
Article Synopsis
- The text discusses the link between environmental factors, oral bacteria, and periodontal disease, highlighting the role of Filifactor alocis in the disease process.
- Filifactor alocis demonstrates the ability to withstand oxidative stress, which enhances its pathogenic potential and alters the oral microbial community.
- Researchers have identified a specific protein, FA519, that aids in oxidative stress resistance, suggesting Filifactor alocis could serve as a potential diagnostic marker for periodontal disease, although further research is needed to understand its virulence.