Association of Favorable Cerebrospinal Fluid Markers With Reversion of Mild Cognitive Impairment Due to Parkinson's Disease.

Objective: Cognitive impairment is a common nonmotor symptom among individuals with Parkinson's disease (PD). Although cognitive impairment generally develops progressively, individuals with PD-associated mild cognitive impairment (PD-MCI) may revert to being cognitively normal (CN), which is referred to as PD-MCI reversion. Previous studies are inconsistent in whether PD-MCI reverters are at greater risk for PD-MCI recurrence relative to CN individuals.

Does qSOFA score predict ICU admission and outcomes in patients with obstructed infected ureteral stones?

Introduction: Obstructing stones with infection represent a true urologic emergency requiring prompt decompression. Historically the systemic inflammatory response syndrome (SIRS) criteria has been used to predict outcomes in patients with sepsis. The quick Sequential Organ Failure Assessment (qSOFA) score has been proposed as a prognostic factor in patients with acute pyelononephritis associated with nephrolithiasis.

Dysphagia Severity and Outcomes Following Iatrogenic High Vagal Nerve Injury.

Objective: To examine severity of dysphagia and outcomes following iatrogenic high vagal nerve injury.

Methods: Retrospective chart review of all patients with iatrogenic high vagal nerve injury that were seen at a tertiary referral center from 2012 to 2020.

Results: Of 1304 patients who met criteria for initial screening, 18 met all inclusion criteria.

Achieving American Nurses Credentialing Center Magnet® Designation With a Virtual Site Visit.

Innovation has enabled organizations to highlight and engage during the COVID -19 pandemic. The use of virtual site visits to assess the organizations 's culture and sustainability of the Magnet components during initial designation and redesignation allows for ongoing support of nursing excellence.

Structured Mentorship and the Nursing Clinical Ladder.

Unlabelled: When nursing turnover is greater than the national average, professional development of nursing staff increases job satisfaction and employment retention. One approach that can address the professional development is mentoring.

Purpose: The evidence-based practice (EBP) project's aim was to determine whether a short-term structured mentorship program led by a clinical nurse specialist increased work engagement among staff nurses within 8 to 10 weeks.

Novel virtual reality based training system for fine motor skills: Towards developing a robotic surgery training system.

Background: Training surgeons to use surgical robots are becoming part of surgical training curricula. We propose a novel method of training fine-motor skills such as Microscopic Selection Task (MST) for robot-assisted surgery using virtual reality (VR) with objective quantification of performance. We also introduce vibrotactile feedback (VTFB) to study its impact on training performance.

What Guidewire Is the Best for Bypassing an Impacted Ureteral Stone?

To determine the optimal guidewire for bypassing an impacted ureteral stone. Three different benchtop models of varying impaction (300, 362, and 444 mm Hg pressure) were used to compare the ability of 13 different guidewires to bypass an impacted ureteral stone. In the first and second models, we recorded the maximum force required to bypass the stone.

Coding source localization through inter-spike delay: modelling a cluster of Pacinian Corpuscles using time-division multiplexing approach.

The Pacinian Corpuscle (PC) is the most sensitive mechanoreceptor in the human body found in clusters of two or three. We extended our previous model of an isolated-PC to a cluster-PC focussing on relative spike delay and displacement threshold for understanding how the stimulus location is coded. In our model, two PCs with Gaussian overlapping receptive fields are arranged beneath the skin model.

The Effect of Operative Field Instrument Clutter During Intraoperative Fluoroscopy on Radiation Exposure.

Fluoroscopy units are routinely operated in the automatic brightness control (ABC) mode to optimize image quality. During ureteroscopy, objects may be placed within the fluoroscopy beam and the effect upon radiation exposure is unknown. The purpose of this study is to investigate the effects of equipment within the fluoroscopy beam during simulated ureteroscopy.

A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.

Objective: To compare the efficacy of pain control and opioid consumption between patients who receive opioid as primary analgesic therapy and those who receive ibuprofen.

Study Design: Prospective randomized trial.

Setting: Tertiary care academic hospital.

Congenital nasal pyriform aperture stenosis in association with solitary median maxillary central incisor: unique radiologic features.

Solitary median maxillary central incisor (SMMCI) coexists in 34%-65% of patients initially diagnosed with congenital nasal pyriform aperture stenosis. SMMCI, a genetic syndrome, warrants consideration for further screening because of its high prevalence of other diagnostic possibilities-specifically central defects, like nasal obstruction and hypothalamo-pituitary axis abnormalities. We report on a presentation of SMMCI with congenital nasal pyriform aperture stenosis which highlights the unique radiologic features and notes the relationship between these two central associated findings in the literature.

Discriminating the effects of Cannabis sativa and Cannabis indica: a web survey of medical cannabis users.

Objective: To evaluate the opinions of medical cannabis (MC) users on the effects of Cannabis indica vs. those of Cannabis sativa on conditions and symptoms through an online survey.

Design: Survey of 95 non-randomly assigned MC users.

A rare sequence variant in intron 1 of THAP1 is associated with primary dystonia.

Although coding variants in THAP1 have been causally associated with primary dystonia, the contribution of noncoding variants remains uncertain. Herein, we examine a previously identified Intron 1 variant (c.71+9C>A, rs200209986).

Economics of epilepsy surgery.

Objective: Surgical decision-making is a complex process. First, a medical decision is made to determine if surgery is necessary. Second, another medical decision is made to determine the type of surgery.