1,207 results match your criteria: "Lokmanya Tilak Municipal Medical College & General Hospitals[Affiliation]"

Background: The technical challenges associated with the removal of small nodules in challenging locations rather than peripheral locations remain unaddressed. We sought to illustrate the parenchymal-sparing surgical approach employed for deep interlobar lung cancer with fused fissures (DILCFFs).

Methods: A retrospective review of 43 patients with cT1N0M0 DILCFFs from January 2013 through December 2022 was performed.

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Background Context: On radiopathological examination of spinal tuberculosis (TB), two predominant forms are known: dry and wet types. Wet TB, as the name suggests, has abscess formation as its predominant presenting feature and is the exudative form; dry TB includes caseation and sequestration with minimal exudate. Dry TB often exhibits poorer recovery patterns than the wet counterparts, which can be possibly ascribed to vasculitis, ischemia, or tubercular myelitis, rather than isolated mechanical compression.

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Background: Sexual harassment (SH) and Gender discrimination (GD) faced by medical students have been neglected areas of study in India. Only a few recent studies could be found, despite frequent media reports on SH and GD. This study aimed to assess the attitudes and perceptions of sexual harassment and gender discrimination and evaluate the forms of SH and GD experienced by them.

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Introduction: Road traffic accidents (RTA) account for a sizable portion of morbidity and mortality globally, with a particularly high incidence among young and active individuals. Patients presenting with polytrauma require a multidisciplinary approach guided by protocols for advanced trauma life support.

Case Report: We report the case of a 31-year-old female, transferred-in to our center following primary care after an RTA on June 17th, 2023.

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Background: There is lack of data on bipolar disorder (BD) type II from India.

Aim: To compare the demographic and clinical characteristics of patients with BD-I and BD-II using the data of the Bipolar Disorder Course and Outcome study from India (BiD-CoIN study).

Methodology: Using the data of the BiD-CoIN study, patients with BD-I and BD-II were compared for demographic and clinical variables.

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A girl in early adolescence presented with complaints of abdominal pain lasting for 4 months, along with a palpable lump in the epigastric region. A CT scan revealed a large solid-cystic mass lesion measuring 9.5×10.

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Rickets in children usually present with skeletal manifestations. However, they can also rarely present with extraskeletal manifestations, one of them being respiratory insufficiency. We present an unusual case of a girl in early childhood with respiratory insufficiency, which turned out to be due to the underlying vitamin D-dependent rickets (VDDR).

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A man in his early 50s presented to the emergency department (ED) with sudden onset of palpitation and presyncope. The 12-lead electrocardiogram (ECG) recorded in ED showed monomorphic ventricular tachycardia requiring cardioversion in view of haemodynamic instability. The patient was subsequently detected to have an anomalous left coronary artery origin from the pulmonary artery.

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 Fractures of the condylar region of the mandible, although fairly common, also generate the most debate regarding management-both closed and open treatment options have been recommended and shown to yield good results. We present our experience with a minimal access retromandibular approach to fractures of the vertical mandible.  This is a retrospective study of all patients who underwent open reduction and internal fixation for fractures of the vertical mandible (condyle, subcondylar region, ramus) using a retromandibular approach at a tertiary care hospital in a metropolitan city in India between January 2022 and July 2023.

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This study investigated the clinical profile, etiology, and outcomes of eosinophilia in hospitalized patients. A total of 96 patients were included, with a mean eosinophil count of 3347.66 ± 1517.

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The rapid rise and potential of artificial intelligence (AI) have created growing excitement and much debate on its potential to bring transformative changes across entire industries, including the medical industry. This systematic review aims to investigate the advancements in the AI industry and its potential implementation, specifically in the field of anaesthesiology. AI has already been integrated into different areas of medicine, including diagnostic uses in radiology and pathology and therapeutic and interventional uses in cardiology and surgery.

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Mapping anti-diphtheria toxin antibody: a systematic review and meta-analysis with multi-level meta-regression.

Pathog Glob Health

December 2024

Center for Global Health Research, Saveetha Medical College and Hospital, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

Diphtheria is a reemerging vaccine-preventable infection of public health concern. Pooled estimates of serum IgG anti-diphtheria antibody levels can assist in estimating the susceptible population. The objective was to estimate pooled estimate of protective IgG anti-diphtheria antibodies in population globally.

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Patients seeking reconstructive facial surgery desire aesthetically pleasing outcomes with minimal visible scarring. For scalp incisions, beveled angle of 45° is typically preferred to preserve hair follicles. However, no consensus exists regarding the ideal incision angle for the brow area.

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A gastrointestinal (GI) transmural defect is defined as a total rupture of the GI wall and these defects can be divided into three main categories, including perforation, leaks and fistulae. Recognition of the specific classification of the defect is important for choosing the best therapeutic modality. We present a case series of patients with gastrointestinal transmural defects which were managed with indigenously modified endoluminal vacuum-assisted closure.

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Status of sperm mitochondrial functions and DNA methylation in infertile men with clinical varicocele before and after treatment.

Mol Cell Endocrinol

January 2025

Department of Neuroendocrinology, ICMR-National Institute for Research in Reproductive and Child Health, Parel, Mumbai, 400012, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. Electronic address:

Varicocele has been associated with reduced male fertility potential. Treatment modalities for varicocele improve semen parameters, yet more than 50% of cases remain infertile. Varicocele-induced heat and hypoxia stress may affect sperm mitochondrial functions, possibly leading to aberrant epigenetic modifications.

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Pharmacotherapy has deinstitutionalized the patients with psychotic disorder. This has led to the transfer of the caregiving burden from hospitals to family members of the patients. This study aimed to assess the caregivers' burden and the factors associated with it objectively.

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A female toddler presented with short stature and hypermobility of limbs. She had sustained five long bone fractures following minor trauma since early infancy. Skeletal survey was consistent with osteogenesis imperfecta.

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Background: There is a lack of information on the long-term course and outcomes of bipolar disorder (BD) patients with seasonal affective disorder (SAD).

Aim: To compare the demographic and clinical profile of BD patients with and without SAD.

Methodology: Data from 773 BD patients with an illness duration of at least 10 years were collected from 14 tertiary care centers.

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Redefining Aging: A Tale of Hutchinson-Gilford Progeria Syndrome.

J Assoc Physicians India

October 2024

Professor and Unit Head, Department of Internal Medicine, Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India.

Article Synopsis
  • Hutchinson-Gilford syndrome, commonly known as progeria, is a rare genetic disorder that leads to dwarfism and premature aging, particularly affecting the heart and blood vessels.
  • Diagnosis involves recognizing specific clinical signs and imaging results, with confirmation through the identification of mutations in the Lamin A gene.
  • The case presented describes a patient who experienced heart failure and brain infarcts, highlighting the uniqueness of the syndrome and the vascular complications associated with it.
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Article Synopsis
  • The study investigated 69 COVID-19 patients with mucormycosis, focusing on their clinical presentation, risk factors, complications, and in-hospital results over seven months from March to September 2021.
  • The majority of patients were male, around 52.8 years old, with most developing mucormycosis within 30 days of COVID-19; common symptoms included facial pain and vision loss, and diabetes was prevalent in 98.6% of cases.
  • The overall mortality rate was 26.1%, with severe cases requiring intensive care linked to factors such as chronic kidney disease and current COVID-19 infection, indicating a heightened risk for these patients.
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Background Young-onset type 2 diabetes mellitus (T2DM), defined as a diagnosis before the age of 45, is an increasingly common and aggressive form of diabetes. This population is at a heightened risk of developing complications earlier in life due to longer disease duration and often suboptimal glycemic control. Complications such as diabetic neuropathy, retinopathy, and nephropathy are significant concerns, leading to reduced quality of life and increased morbidity.

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The luminal separation of the vessel into two distinct, parallel channels that reunite distantly is known as fenestration. There is a correlation between the development of an aneurysm and the proximal portion of fenestration, although fenestrations are typically regarded as a variant of normal anatomy. We report an interesting case of an anterior communicating artery (a-comm) aneurysm, which turns out to be a ruptured fenestrated A1 segment aneurysm after digital subtraction angiography with concomitant multiple aneurysms treated by clipping along with case report and literature review.

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Background: Feedback on the diagnostic process has been proposed as a method of improving clinical reasoning and reducing diagnostic errors. Barriers to the delivery and receipt of feedback include time constraints and negative reactions. Given the shift toward asynchronous, digital communication, it is possible that electronic feedback ("e-feedback") could overcome these barriers.

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