8 results match your criteria: "Lokman Hekim University Faculty of Pharmacy[Affiliation]"
Cell Biochem Funct
March 2024
Ministry of Health, General Directorate of Public Health, Microbiology References Laboratory, Ankara, Turkey.
Multidrug-resistant strains of Acinetobacter baumannii cause major nosocomial infections. Bacteriophages that are specific to the bacterial species and destroy bacteria can be effectively used for treatment. In this study, we characterized lytic bacteriophages specific to A.
View Article and Find Full Text PDFJ Microbiol Methods
July 2023
Department of Pharmaceutical Microbiology, Ankara University Faculty of Pharmacy, Ankara, Turkey.
Acinetobacter baumannii (A. baumannii) is considered a critical human pathogen due to multi-drug resistance and increased infections. As a result of the resistance of A.
View Article and Find Full Text PDFTurk J Surg
September 2022
Department of General Surgery, Kütahya Health Science University, Kütahya, Türkiye.
Objectives: Hepatic ischemia-reperfusion (IR) injury occurs in liver surgery, resection, and transplantation. Reactive oxygen species (ROS) produced following IR starts the cascade of cell damage, necrosis/apoptosis, and proinflammatory responses by activating intracellular signaling cascade to drive hepatocellular damage. Cerium oxide nanoparticles (CONPs) act as anti-inflammatory and antioxidant agents.
View Article and Find Full Text PDFEvid Based Complement Alternat Med
February 2022
Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.
belongs to the Urticaceae family and is found in many countries around the world. This plant contains a broad range of phytochemicals, such as phenolic compounds, sterols, fatty acids, alkaloids, terpenoids, flavonoids, and lignans, that have been widely reported for their excellent pharmacological activities, including antiviral, antimicrobial, antihelmintic, anticancer, nephroprotective, hepatoprotective, cardioprotective, antiarthritis, antidiabetic, antiendometriosis, antioxidant, anti-inflammatory, and antiaging effects. In this regard, this review highlights fresh insight into the medicinal use, chemical composition, pharmacological properties, and safety profile of to guide future works to thoroughly estimate their clinical value.
View Article and Find Full Text PDFArh Hig Rada Toksikol
June 2020
Lokman Hekim University Faculty of Pharmacy, Department of Toxicology, Ankara, Turkey.
Aroclor 1254 (A1254), a mixture of polychlorinated biphenyls, exerts hepatic, renal, and reproductive toxicity in rodents. This study aimed to determine a protective role of selenium on histopathological changes, oxidative stress, and apoptosis caused by A1254 in rat kidney. It included a control group, which received regular diet containing 0.
View Article and Find Full Text PDFTurk J Pharm Sci
June 2020
Lokman Hekim University Faculty of Pharmacy, Department of Pharmacology, Ankara, Turkey.
Cardiopulmonary diseases are very common among the population. They are high-cost diseases and there are still no definitive treatments. The roles of members of the calcitonin-gene related-peptide (CGRP) family in treating cardiopulmonary diseases have been studied for many years and promising results obtained.
View Article and Find Full Text PDFTurk J Pharm Sci
April 2020
Ankara University Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.
Objectives: In the present study, the antioxidant potency of ethyl acetate (AcOEt) and methanol (MeOH) extracts from the aerial parts of L. species was investigated for the first time.
Materials And Methods: species L.
Reprod Toxicol
August 2019
Department of Pediatrics, Neonatology Unit, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Bisphenol A (BPA) and phthalates can adversely affect the fetal development. However, observational studies on the effects of these chemicals on fetal male reproductive system are still limited. A hundred of umbilical cord blood samples were analyzed for the levels of BPA, di-2-ethylhexyl phthalate (DEHP), mono-2-ethylhexyl phthalate (MEHP), and sex hormones.
View Article and Find Full Text PDF