The primary perfluoroalcohols CF OH, C F OH, and nC F OH were synthesized using carbonyl compounds in anhydrous HF solution.
Experimental reaction enthalpies and entropies were calculated from the temperature-based equilibria of certain reactions monitored through NMR spectroscopy.
Computational chemistry methods indicated that these perfluoroalcohols are strong acids, and their protonation in HF/SbF formed perfluoroalkyl oxonium salts.