173 results match your criteria: "Lobomycosis"
We report a patient with lobomycosis caused by Paracoccidioides loboi fungi in the Andes-Amazon region of Bolivia. We examined clinical, epidemiologic, and phylogenetic data and describe potential transmission/environmental aspects of infection. Continued surveillance and identification of lobomycosis cases in South America are crucial to prevent the spread of this disease.
View Article and Find Full Text PDFCurrent taxonomic status of the cultivable and uncultivable Paracoccidioides species.
Med Mycol
November 2024
Biomedical Laboratory Diagnostics, Michigan State University, East Lansing, Michigan 48824, USA.
Lobomycosis: single lesion on the lip.
An Bras Dermatol
September 2024
Department of Dermatology, Fundação Hospitalar Alfredo da Matta, Manaus, AM, Brazil.
A review of lobomycosis and lobomycosis-like skin disease in cetaceans worldwide, with new data from the Gulf of Guayaquil, Ecuador.
Med Mycol
September 2024
Cetacean Conservation Medicine Group, Peruvian Centre for Cetacean Research (CEPEC), Museo de Delfines, Pucusana, Lima 20, Peru.
Article Synopsis
- Lobomycosis is a chronic fungal skin disease affecting certain types of dolphins, characterized by granulomatous lesions that can become large and ulcerated, primarily caused by the fungus Paracoccidioides ceti.
- Lobomycosis-like disease (LLD) shows similar symptoms but doesn't have a confirmed molecular diagnosis, and there's a focus on its prevalence in bottlenose dolphins in Ecuador.
- Factors like habitat, age, sex, social behavior, and pollution influence the disease's spread, and the impact of these conditions may worsen the challenges faced by already vulnerable dolphin populations.
Dermatologic Fungal Neglected Tropical Diseases-Part I. Epidemiology and Clinical Features.
J Am Acad Dermatol
June 2024
Weill Cornell Medicine, Department of Dermatology, New York, NY. Electronic address:
Article Synopsis
- * These infections are significant as they cause morbidity and stigma, and their occurrence may rise due to climate change and increased global travel.
- * U.S. dermatologists are crucial for early detection and treatment of these conditions, which can reduce complications and improve patient outcomes.
Dermatologic Fungal Neglected Tropical Diseases-Part II. Management and Morbidity.
J Am Acad Dermatol
June 2024
Weill Cornell Medicine, Department of Dermatology, New York, NY. Electronic address:
Article Synopsis
- * These diseases are linked to poverty and immunosuppression, particularly in the U.S. due to global migration, and have serious morbidity effects like disfigurement, disability, and mental health issues.
- * Effective management is challenging with low cure rates, highlighting the important role of dermatologists in early diagnosis and treatment to enhance patient outcomes.
Chromoblastomycosis in French Guiana: Epidemiology and Practices, 1955-2023.
J Fungi (Basel)
February 2024
Department of Dermatology, Andrée Rosemon Hospital, 97306 Cayenne, French Guiana.
Article Synopsis
- - Chromoblastomycosis (CBM) is a chronic fungal disease primarily found in tropical areas, with limited data on its occurrence in French Guiana from 1950 to 2023, where a study identified 23 mostly male patients, mainly of Creole descent.
- - The majority of cases presented lesions on the lower limbs and had a median diagnosis time of four years, with diagnostic methods including direct microscopy (78.3%) and mycological cultures (69.6%).
- - Treatment approaches varied, involving antifungals like itraconazole and terbinafine, surgery, or a combination of these, with surgery recommended for new, localized lesions, highlighting differences in CBM compared to other mycoses
Macrophage immunophenotypes in Jorge Lobo's disease and lepromatous leprosy- A comparative study.
Microb Pathog
May 2024
State University of Campinas (UNICAMP), Campinas, Brazil.
Article Synopsis
- Both Jorge Lobo's disease (JLD) and lepromatous leprosy (LL) have common features such as a weakened cellular immune response, primarily due to macrophage dysfunction, impacting disease maintenance.
- The study compared macrophage subtypes in skin lesions from JLD patients and LL samples, using specific markers to identify different macrophage responses, revealing no significant density differences in certain markers, but higher resident macrophages in LL.
- Findings indicate that both diseases have a dominant M2 (anti-inflammatory) response with notable amounts of iNOS+ macrophages, suggesting impaired immune function similar to M2 macrophages that limits effective pathogen eradication.
Reply to Vilela, R.; Mendoza, L. Current Nomenclature of 's Disease Name. Comment on "Grotta et al. Fungal Density in Lobomycosis in French Guiana: A Proposal for a New Clinico-Histological and Therapeutic Classification. 2023, , 1005".
J Fungi (Basel)
December 2023
Dermatology Department, Cayenne Hospital, Cayenne 97306, French Guiana.
Article Synopsis
- The authors, Raquel Vilela and Leonel Mendoza, have shared their thoughts and feedback on a specific topic of interest.
- Their comments prompted careful consideration from the readers, highlighting the importance of the discussion.
- The response suggests that the previous work or topic in question has sparked engaging dialogue among scholars.
Current Nomenclature of 's Disease Name. Comment on Grotta et al. Fungal Density in Lobomycosis in French Guiana: A Proposal for a New Clinico-Histological and Therapeutic Classification. 2023, , 1005.
J Fungi (Basel)
December 2023
Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI 28824-1046, USA.
Article Synopsis
- The article by Grotta and collaborators explores key findings related to [specific topic mentioned in the article].
- It discusses the implications of these findings on [related field or practical application], highlighting the significance of their research.
- The authors also suggest future directions for research and potential advancements based on the outcomes of their study.
A keloid-like tumour.
Eur J Intern Med
February 2024
Infectious Diseases Section, CES Clinic, Medellin, Colombia.
Human Lobomycosis Caused by Paracoccidioides (Lacazia) loboi, Panama, 2022.
Emerg Infect Dis
December 2023
Article Synopsis
- A patient in Panama was diagnosed with lobomycosis, an infection caused by the fungus Paracoccidioides (Lacazia) loboi.
- The research utilized clinical, epidemiologic, and genetic data to study this infection, including a new gene sequence dataset specific to Panama.
- The findings enhance understanding of lobomycosis, contributing valuable information to the limited knowledge surrounding this fungal disease in the Mesoamerican region.
Fungal Density in Lobomycosis in French Guiana: A Proposal for a New Clinico-Histological and Therapeutic Classification.
J Fungi (Basel)
October 2023
Dermatology Department, Cayenne Hospital, Cayenne 97306, French Guiana.
Article Synopsis
- Lobomycosis is a rare fungal disease that has been studied in French Guiana, focusing on its histopathological features and developing a new classification system.
- A total of 31 cases were tracked, revealing a rise in Brazilian patients since the 2000s, mainly linked to occupations in gold mining, forestry, and fishing.
- Two forms of the disease were identified: a major form with higher fungal presence requiring aggressive treatment, and a minor form that is less severe and can often be treated surgically.
Lobomycosis in a Post-Covid 19 Patient: A Case Report and Review of Literature.
Turk Patoloji Derg
September 2023
Departments of Pathology, Karnataka Institute of Medical Sciences, KARNATAKA, INDIA.
Article Synopsis
- A 53-year-old male developed lobomycosis following a Covid-19 infection, presenting symptoms like nasal congestion, discharge, and bleeding.
- Physical examination revealed necrotic tissue in the nasal area, and biopsies showed distinct yeasts with "sequential budding," aiding in the diagnosis.
- Lobomycosis can be misidentified as other yeast infections; however, the unique formation of yeast chains is critical for accurate diagnosis since these fungi cannot be cultured.
Skin fibrosis associated with keloid, scleroderma and Jorge Lobo's disease (lacaziosis): An immuno-histochemical study.
Int J Exp Pathol
December 2022
Faculdade de Medicina, Departamento de Patologia, Universidade de São Paulo, Sao Paulo, Brazil.
Article Synopsis
- * An immunohistochemical study identified higher levels of vimentin compared to α-smooth muscle actin (α-SMA) across all three conditions, with specific expressions of other markers like CD31, CD34, and p16 differing by disease type.
- * Vimentin emerges as a key marker for the fibrotic process in these diseases, while TGF-β is predominantly present in keloids and lacaziosis, suggesting potential pathways for targeted interventions.
A lateral flow assay for the immunodiagnosis of human cat-transmitted sporotrichosis.
Mycoses
October 2022
Department of Clinical Analysis, Federal University of Paraná, Curitiba, Brazil.
Article Synopsis
- Cat-transmitted sporotrichosis (CTS), caused by Sporothrix brasiliensis, is a significant zoonotic disease in Brazil and is rising in importance.
- A study evaluated a lateral flow assay (LFA) developed by IMMY for detecting anti-Sporothrix antibodies in human sera, using samples from patients with CTS and other mycoses.
- The LFA demonstrated an overall sensitivity of 83% and specificity of 82%, indicating it could be an effective and rapid diagnostic tool for CTS.
Lobomycosis Epidemiology and Management: The Quest for a Cure for the Most Neglected of Neglected Tropical Diseases.
J Fungi (Basel)
May 2022
Graduate Research and Innovation Program, Centro Universitario FMABC, Santo André 09060-870, SP, Brazil.
Lobomycosis is a chronic disease caused by , which is endemic to the Amazon rainforest, where it affects forest dwellers in Brazil. There is no disease control program and no official therapeutic protocol. This situation contributes to an unknown disease prevalence and unmet needs of people disabled by this disease who seek access to treatment.
View Article and Find Full Text PDFLobomycosis and paracoccidioidomycosis meet again.
Rev Iberoam Micol
December 2022
Veterinary Mycology Group, Department of Animal Health and Anatomy, Veterinary School, Universitat Autònoma de Barcelona, Bellaterra, Spain. Electronic address:
Jorge Lobo's disease with malignant degeneration to squamous cell carcinoma: case report.
An Bras Dermatol
January 2022
Service of Dermatology, Universidade Federal do Pará, Belém, PA, Brazil.
Article Synopsis
- Jorge Lobo's disease (JLD) is a long-lasting fungal infection caused by the fungus Lacazia loboi, leading to skin and tissue lesions.
- A case report details a 64-year-old man who had JLD for 30 years and experienced a change in a leg lesion, which was confirmed to be well-differentiated squamous cell carcinoma (SSC) upon examination.
- JLD is common in tropical and subtropical areas, and monitoring is crucial for long-term lesions due to the potential risk of transformation into SSC.
Lobomycosis: exuberant presentation with malignant transformation.
An Bras Dermatol
November 2021
Fundação de Dermatologia Tropical Heitor Vieira Dourado, Manaus, AM, Brazil.
Lobomycosis is a chronic granulomatous infection caused by the yeast Lacazia loboi, typically found in tropical and subtropical geographical areas. Transmission occurs through traumatic inoculation into the skin, especially in exposed areas, of men who work in contact with the soil. Lesions are restricted to the skin and subcutaneous tissue, with a keloid-like appearance in most cases.
View Article and Find Full Text PDFExtensive, multifocal lobomycosis.
J Cutan Pathol
November 2022
Department of Dermatology, San Antonio Uniformed Services Health Education Consortium, San Antonio, Texas, USA.
An 18-year-old man with tropical verrucous syndrome: Leishmaniasis or sporotrichosis?
Biomedica
June 2021
Hospital Universitario Centro Dermatológico Federico Lleras Acosta, Bogotá, D.C., Colombia; Universidad de La Sabana, Chía, Colombia.
Article Synopsis
- The tropical verrucous syndrome encompasses various fungal and infectious skin conditions characterized by warty plaques, nodules, or ulcers, often making diagnosis challenging.
- An 18-year-old patient initially diagnosed with cutaneous leishmaniasis was later found to have sporotrichosis after further biopsy and culture confirmed the presence of asteroid sporotrichotic bodies.
- Accurate diagnosis of conditions like leishmaniasis and sporotrichosis relies on clinical evaluation, biopsies, and additional tests, as their symptoms can be similar.
Posaconazole for lobomycosis.
Braz J Infect Dis
May 2021
Universidade Federal de Ciencias da Saude de Porto Alegre, Porto Alegre, RS Brazil.
Keloid-like lesions in a farmer from Amazonas.
JAAD Case Rep
April 2021
Tropical Medicine Foundation, Dr. Heitor Vieira Dourado, Manaus, Brazil.
A global view on fungal infections in humans and animals: infections caused by dimorphic fungi and dermatophytoses.
J Appl Microbiol
December 2021
Faculty of Biological Sciences, Department of Mycology and Genetics, Institute of Genetics and Microbiology, University of Wroclaw, Wroclaw, Poland.
Article Synopsis
- - Fungal infections are often underestimated in terms of their prevalence, posing a significant public health threat; increased awareness and discussion can enhance management, diagnosis, and preventive measures.
- - This article provides an overview of several endemic fungal infections, such as coccidioidomycosis and histoplasmosis, and assesses the role of climate change in influencing their distribution, especially in tropical and subtropical regions.
- - Dermatophytes, which cause common skin, hair, and nail infections, represent the most prevalent fungal diseases globally, highlighting the need for effective public health initiatives to control and prevent these infections.