6 results match your criteria: "Liverpool University Hospital NHS FT[Affiliation]"
Coronary Artery Calcium Score Predicts Major Adverse Cardiovascular Events in Stable Chest Pain.
Radiology
March 2024
From the Department of Radiology (F.B., E.Z., A.E.N., R. Haase, S.F., M. Mohamed, M.R., V.W., M.E., M. Bosserdt, M.D.), Institute of Public Health (N.R.), Institute of Biometry and Clinical Epidemiology (K.N.), and Department of Cardiology and Angiology (H.D.), Charité-Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität zu Berlin, Charitéplatz 1, 10117 Berlin, Germany; Department of Radiology, University of Cagliari, Cagliari, Italy (L.S., R.C.); Heart and Vascular Center (M. Boussoussou, P.M.H., B.M., B.S., I.F.É.) and Department of Radiology, Medical Imaging Center (P.M.H.), Semmelweis University, Budapest, Hungary; Departments of Cardiology (K.F.K., P.E.S.) and Radiology (K.F.K., P.E.S.), Copenhagen University Hospital-Rigshospitalet and Department of Clinical Medicine (J.D.H.), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Internal Medicine, Clinic of Cardiology (T.B., R. Hodas), and Department of Cardiology (R.A.), George Emil Palade University of Medicine, Pharmacy, Science and Technology, Targu Mures, Romania; County Clinical Emergency Hospital Targu Mures, Targu Mures, Romania (T.B.); Department of Cardiology, Southeastern Health and Social Care Trust, Belfast, United Kingdom (P.D., C.O., S.K., S.R.); Departments of Cardiology (J.R.P., F.X.V., B.G.d.B.) and Radiology (H.C.C.), Hospital Universitario Vall d'Hebron, Institut de Recerca, Universitat Autònoma de Barcelona, Barcelona, Spain; Centro de Investigación Biomédica en Red, Madrid, Spain (J.R.P., F.X.V., B.G.d.B.); Departments of Cardiology (A.E.) and Radiology (L.Z.), Paul Stradins Clinical University Hospital, Riga, Latvia; University of Latvia, Riga, Latvia (A.E.); Departments of Cardiology (C.Š.) and Imaging Methods (V.S.), Motol University Hospital, Prague, Czech Republic; Department of Cardiology, Medical Academy (G.Š.), and Department of Radiology (A.J.), Hospital of Lithuanian University of Health Sciences, Kaunas, Lithuania; Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia (N.Č.A., F.A.); Department of Cardiology, Institute for Cardiovascular Diseases of Vojvodina, Novi Sad, Serbia (N.Č.A., F.A.); Departments of Radiology (M.G.) and Cardiology (M.W.), University of Leipzig Heart Centre, Leipzig, Germany; Departments of Radiology (J.D.D.) and Cardiology (D.C.), St. Vincent's University Hospital, Dublin, Ireland; School of Medicine, University College Dublin, Dublin, Ireland (J.D.D.); Departments of Cardiology (I.D., A.R.) and Radiology (I.L.), Basurto Hospital, Bilbao, Spain; Departments of Cardiology (G.D.) and Radiology (E.T.), Aintree University Hospital, Liverpool, United Kingdom; Edge Hill University, Ormskirk, United Kingdom (G.D.); National Institute of Cardiology, Warsaw, Poland (C. Kępka, M.K.); Department of Cardiology, Internal Medicine Clinic, Clinical Hospital Center Zemun, and Faculty of Medicine, University of Belgrade, Belgrade, Serbia (R.V., A.N.N.); Department of Radiological, Oncological and Pathological Sciences (M. Francone) and Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences (M. Mancone), Sapienza University of Rome, Rome, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy (M. Francone); Departments of Cardiology (M.I.S.) and Radiology (D.K.), Provincial Specialist Hospital in Wroclaw, Wroclaw, Poland; Departments of Internal Medicine III (F.P.), Cardiology (F.P.), and Radiology (G.F.), Innsbruck Medical University, Innsbruck, Austria; Turku PET Centre (J.K.) and Heart Center (M.P.), Turku University Hospital and University of Turku, Turku, Finland; Department of Cardiology, Centro Hospitalar de Vila Nova de Gaia-Espinho, Vila Nova de Gaia, Portugal (R.F., V.G.R.); Department of Cardiology, Alb Fils Kliniken, Göppingen, Germany (S.S., T.D.); School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, United Kingdom (C.B., C.D.); Golden Jubilee National Hospital, Clydebank, United Kingdom (C.B.); Department of Cardiology, Liverpool University Hospital NHS FT, Liverpool, United Kingdom (B.R., M. Fisher); Institute for Cardiovascular Medicine and Science, Liverpool Heart and Chest Hospital, Liverpool, United Kingdom (B.R., M. Fisher); European Clinical Research Infrastructure Network-European Research Infrastructure Consortium (ECRIN-ERIC), Paris, France (C. Kubiak); Department of Public Health, Section for Health Services Research, University of Copenhagen, Copenhagen, Denmark (K.S.H.); Bavarian Cancer Registry, Bavarian Health and Food Safety Authority, Munich, Germany (J.M.N.); Center of Advanced Research in Multimodality Cardiac Imaging, CardioMed Medical Center, Targu Mures, Romania (I.B., I.R.); Administrative Centre, Health Care District of Southwestern Finland, Turku, Finland (M.P.); Faculty of Health and Life Sciences, University of Liverpool, Liverpool, United Kingdom (M. Fisher); Department of Cardiology, Hillerød Hospital, University of Copenhagen, Copenhagen, Denmark (C. Kragelund); Department of Cardiology, Copenhagen University Hospital-Amager and Hvidovre, Hvidovre, Denmark (J.D.H.); Department of Cardiology, Herlev-Gentofte Hospital, Hellerup, Denmark (L.L.); DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany (M. Mohamed, M.D.); Department of Clinical Epidemiology and Applied Biostatistics, Universitätsklinikum Tübingen, Tübingen, Germany (L.M.S.H., P.M.); Deutsches Herzzentrum der Charité (DHZC), Berlin, Germany (H.D., M.D.); Department of Cardiology, Angiology and Intensive Care Medicine, Campus Charité Mitte, Berlin, Germany (H.D.); Department of Cardiology, Lundquist Institute at Harbor-UCLA, Torrance, Calif (M.J.B.); Berlin Institute of Health, Berlin, Germany (M.D.); and Berlin University Alliance, Berlin, Germany (M.D.).
Background Coronary artery calcium (CAC) has prognostic value for major adverse cardiovascular events (MACE) in asymptomatic individuals, whereas its role in symptomatic patients is less clear. Purpose To assess the prognostic value of CAC scoring for MACE in participants with stable chest pain initially referred for invasive coronary angiography (ICA). Materials and Methods This prespecified subgroup analysis from the Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease (DISCHARGE) trial, conducted between October 2015 and April 2019 across 26 centers in 16 countries, focused on adult patients with stable chest pain referred for ICA.
View Article and Find Full Text PDFReal-world experience of nintedanib for progressive fibrosing interstitial lung disease in the UK.
ERJ Open Res
January 2024
Bristol Interstitial Lung Disease Service, North Bristol NHS Trust, Bristol, UK.
Background: Nintedanib slows progression of lung function decline in patients with progressive fibrosing (PF) interstitial lung disease (ILD) and was recommended for this indication within the United Kingdom (UK) National Health Service in Scotland in June 2021 and in England, Wales and Northern Ireland in November 2021. To date, there has been no national evaluation of the use of nintedanib for PF-ILD in a real-world setting.
Methods: 26 UK centres were invited to take part in a national service evaluation between 17 November 2021 and 30 September 2022.
Impact of smoking in patients with suspected coronary artery disease in the randomised DISCHARGE trial.
Eur Radiol
June 2024
Department of Radiology, Charité - Universitätsmedizin Berlin, Freie Universität Berlin and Humboldt-Universität Zu Berlin, Berlin, Germany.
Article Synopsis
- This study aimed to compare the impact of cardiac CT versus invasive coronary angiography (ICA) on cardiovascular events, particularly looking at how smoking status affects these outcomes.
- Results showed that the effectiveness of CT versus ICA in preventing major adverse cardiovascular events (MACE) was similar across different smoking groups, but a CT-first approach notably reduced complications and procedures needed, especially for smokers.
- The findings suggest that a CT-first strategy is beneficial for detecting non-obstructive coronary artery disease in patients with stable chest pain, leading to fewer complications regardless of smoking status.
The role of CPT1A as a biomarker of breast cancer progression: a bioinformatic approach.
Sci Rep
September 2022
Department of Molecular and Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
Breast cancer is the commonest malignancy of women and with its incidence on the rise, the need to identify new targets for treatment is imperative. There is a growing interest in the role of lipid metabolism in cancer. Carnitine palmitoyl-transferase-1 (CPT-1); the rate limiting step in fatty acid oxidation, has been shown to be overexpressed in a range of tumours.
View Article and Find Full Text PDFThe Impact of Demographic, Socio-Economic and Geographic Factors on Mortality Risk among People Living with Dementia in England (2002-2016).
Int J Environ Res Public Health
December 2021
Liverpool University Hospital NHS FT, Liverpool L7 8XP, UK.
Increasing numbers of people living with dementia (PLWD), and a pressured health and social care system, will exacerbate inequalities in mortality for PLWD. There is a dearth of research examining multiple factors in mortality risk among PLWD, including application of large administrative datasets to investigate these issues. This study explored variation mortality risk variation among people diagnosed with dementia between 2002-2016, based on: age, sex, ethnicity, deprivation, geography and general practice (GP) contacts.
View Article and Find Full Text PDFFrailty and cognitive impairment are not reasons to withhold anticoagulation in people with atrial fibrillation but screening could guide management.
J Am Geriatr Soc
July 2021
Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK.