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Considerations for the selection of tests for SARS-CoV-2 molecular diagnostics.

Mol Biol Rep

October 2022

Medical Oncology Group, Ingham Institute for Applied Medical Research, Liverpool Clinical School, School of Medicine, Western Sydney University, and South West Sydney Clinical Campus, UNSW Medicine & Health, Liverpool Hospital NSW, Liverpool, Australia.

During the course of 2020, the outbreak of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) spread rapidly across the world. Clinical diagnostic testing for SARS-Cov-2 infection has relied on the real-time Reverse Transcriptase Polymerase Chain Reaction and is considered the gold standard assay. Commercial vendors and laboratories quickly mobilised to develop diagnostic tests to detect the novel coronavirus, which was fundamentally important in the pandemic response.

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