Characterising equine abdominal lipomata: Can histological features improve the understanding of pathogenesis and risk?

Background: Strangulating lipomata are the most common cause of small intestinal strangulating obstruction. Evaluation of histological features of pathological and non-pathological lipomata, and the histological properties of omental and retroperitoneal fat have not been described.

Objectives: To characterise histological features of equine abdominal lipomata, omental and retroperitoneal adipose tissue, and associations between them.

Intestinal Lipoma Acting as a Lead Point of Intussusception: A Case Series.

Background: Lipomas represent a rare benign etiology of intussusception in adults, affecting both the small intestine and the colon. Diagnosing intussusception in adults can be challenging, and there are no reports on the use of positron emission tomography/CT (PET/CT) in the diagnosis of lipoma-induced intussusception. This study aimed to preliminarily explore the potential diagnostic utility of 18F-FDG PET/CT in the diagnosis of intussusception caused by lipomas.

Case report: chronic expanding hematoma becomes angiosarcoma.

Chronic expanding hematoma is a hematoma that gradually increases in size over a period. Only a few studies reported a chronic expanding hematoma that turned into a malignancy, we report a rare presentation of a chronically expanding hematoma that after 10 years became an angiosarcoma. This is a 41-year-old gentleman, presented to our Emergency Department, complaining of left upper gluteal pain and bleeding after he underwent hematoma evacuation in a private hospital.

A Case of Surgically Treated Adult Split Cord Malformation Type 2 with Tethered Cord Syndrome.

Split cord malformation (SCM) is a rare congenital anomaly characterised by the division of the spinal cord into 2 distinct hemicords, often accompanied by bony or cartilaginous septum. We experienced a surgical case diagnosed as SCM with tethered cord syndrome (TCS) due to spinal lipoma. A 54-year-old female presented with a history of gradually progressive paraparesis and bladder dysfunction for a few months.

Coexisting Non-functioning Pituitary Macroadenoma and Sellar-Suprasellar Lipoma: A Case Report and Literature Review.

Intracranial lipomas are benign tumors that may occasionally be found in the suprasellar cistern while pituitary adenomas are far more common brain tumors. Pituitary adenomas may rarely coexist with other intracranial tumors in the sellar-suprasellar region. We share a unique case of a patient with coexisting non-functioning pituitary adenoma and sellar-suprasellar lipoma presenting with blurring of vision.

Effects of alpelisib treatment on murine -deficient lipomas.

 Phosphatase and tensin homolog (PTEN) hamartoma tumour syndrome (PHTS) is a rare disorder caused by germline mutations in the tumour suppressor gene PTEN, a key negative regulator of phosphatidylinositol 3-kinase (PI3K)/AKT signalling. Children with PHTS often develop lipomas, for which only surgical resection is available as treatment. We investigated the effects of the selective PI3K-inhibitor alpelisib on Pten-deficient lipomas.

Split cord malformations in adults.

Purpose: Split cord malformations represent a small group among tethered cord syndromes. This paper presents the largest series of adult patients with this disorder reported to date. Neuroradiological features, clinical symptoms, surgical management and data on short- and long-term outcomes are analyzed.

Management Algorithm for Atypical Lipomatous Tumours: A Retrospective Case Series.

Introduction: Atypical lipomatous tumours (ALTs), or low-grade well-differentiated liposarcomas (WDLs), can be identified using radiological complex septations and histological atypia. In our view, this is a confusing name that underestimates the risk of local recurrence of such tumours. Defining a management algorithm for differentiating a lipoma from an ALT is important for considering the best management of these patients.

Endobronchial Lipoma Causing Almost Completely Trachea Obstruction.

Even though endobronchial lipoma is rare, it can mimic malignancy and lead to significant complications such as progressive dyspnea and subsequent lung infections related to endobronchial obstruction. We present a case of endobronchial lipoma located in the trachea causing almost complete tracheal obstruction. The patient's dyspnea disappeared after undergoing bronchoscopic excision of the mass.

Nevus lipomatosus superficialis mimicking ectopic breast tissue: A rare case report.

Rationale: Diagnosis of solitary superficial lipomatous mass may vary depending on circumstances. Although preliminary diagnosis can be made through clinical symptoms and imaging studies, final diagnosis can change through histological examination. This is the first reported case of nevus lipomatosus superficialis (NLS) resembling ectopic breast tissue which may provide valuable insights for clinicians managing similar lesions.

Spinal rhabdomyosarcoma in a child at the site of a lumbosacral lipoma: a rare entity.

Malignant tumours arising at the site of closed neural tube defects are extremely rare and have only been described three times in the literature. We report the case of a child with a congenital lumbosacral lipoma, a dermal sinus tract and low-lying spinal cord who was initially treated non-operatively due in part to non-attendance and who then presented at 2 years of age with recurrent urinary tract infections with intermittent pyrexia, back pain and difficulty walking. A craniospinal MRI was performed with suspicion of infection at the site of the closed neural tube defect (in view of the dermal sinus tract) and leptomeningeal spread to the rest of the spine and brain.

Spindle Cell Lipoma of the Fourth Metatarsal: A Case Report.

Spindle cell lipoma (SCL) is a rare subtype of lipoma that typically arises in the subcutaneous tissue of the posterior neck and shoulders, most commonly in middle-aged men, and only rarely occurs in the extremities. SCL typically presents as a well-circumscribed, firm mass composed of CD34-positive adipocytes mixed with bland spindle cells and ropy collagen fibers. We present the case of a 46-year-old man who came to the hospital for routine hemodialysis treatment, during which his physician discovered a mass on his left fourth metatarsal that had been slowly growing for the past five years.

Posterior vertebral column resection for recurrent tethered cord syndrome: a 10-year case series.

Objective: Tethered cord syndrome (TCS) is a significant cause of debilitation in patients with spinal dysraphisms or tumors. Management of TCS has historically centered on intradural detethering surgery, which is associated with a substantial risk of retethering, symptom recurrence, and repeat surgery. Vertebral column resection (VCR) has recently gained popularity as a treatment option via spinal shortening, but the literature on long-term outcomes is sparse.

Diagnostic Dilemma of a Soft Tissue Mass in the Medial Gastrocnemius: A Case Report.

Soft tissue masses in the lower extremities present significant diagnostic challenges due to the broad spectrum of potential etiologies, ranging from benign to malignant tumors. A 69-year-old woman presented to the University of Central Florida-Health Surgical Clinic with an enlarging, firm, ovoid mass in her left gastrocnemius muscle causing increasing mostly emotional and psychological distress. A magnetic resonance imaging (MRI) of the left lower extremity was ordered, and findings suggested a 1.

Resolution of Persistent Radicular Leg Pain After Posterior Lumbar Fusion by Filum Terminale Lipoma Resection: A Case Report.

Case: A 79-year-old woman presented with persistent left leg pain following right-sided L4-5 minimally invasive transforaminal lumbar interbody fusion. Imaging studies revealed residual left L4-5 stenosis, a filum terminale lipoma, and no bone bridging. Additional left L4-5 decompression with reinstrumentation achieved temporary relief, but complete pain resolution was achieved only after sectioning of the filum terminale lipoma causing the tethered cord syndrome.

Laryngeal Fibrolipoma: A Case Report.

Fibrolipoma is a benign mesenchymal tumor with a rare presentation in the aerodigestive tract. This lesion is characterized by a slow growth rate and symptoms such as dysphagia, dysphonia, and dyspnea due to the mass effect on neighboring structures. Achieving optimal surgical outcomes requires indirect laryngoscopy and imaging techniques such as computed tomography (CT) or magnetic resonance imaging (MRI), which provide useful information for a better understanding of the underlying pathology.

A rare case of a rectal neuroendocrine neoplasm growing within a lipoma with ulcerative lesions.

Neuroendocrine neoplasms (NENs) are a heterogeneous group of tumors with different immunophenotypes, morphological features, clinical presentations, and outcomes. Therefore, the diversity of NENs can easily confuse clinicians and lead to misdiagnosis. This article reports a case of a rectal NEN (r-NEN) growing within a lipoma with ulcerative lesions, which had been mistaken for rectal cancer.

A Case Report on Gastric Lipoma: An Unusual Etiology of Gastrointestinal Bleeding.

Gastric lipomas are rare, benign tumors of the stomach. They are often asymptomatic and are typically discovered incidentally during imaging studies or endoscopic evaluations. When symptomatic, they may present with nonspecific gastrointestinal (GI) symptoms such as abdominal pain, bleeding, or obstruction.

Benign Symmetric Lipomatosis of the Tongue With Dysgeusia: A Case Report and Literature Review.

Benign symmetric lipomatosis (BSL) is a rare disorder that is characterized by diffuse growth, multiple symmetrical accumulation, and unencapsulated lipomas. BSL is also known as Madelung disease, Launois-Bensaude syndrome, and multiple symmetric lipomatosis. BSL is commonly found in the upper trunk and posterior neck.

Hidden in Plain Sight: Incidental Diagnosis of Metastatic Papillary Thyroid Microcarcinoma Without Radiologically Apparent Thyroid Tumor.

Background/objective: Papillary thyroid cancer (PTC) is considered the most common form of thyroid cancer. Papillary thyroid microcarcinomas (PTMCs) are defined as papillary carcinomas that are <1 cm and are often identified on surgical pathology but may be missed by ultrasound imaging.

Case Report: Our case describes a 24-year-old woman who initially presented with a right lateral neck lump.

Haberland Syndrome (Encephalocraniocutaneous Lipomatosis): A Case Report and Review of Literature.

Encephalocraniocutaneous lipomatosis (ECCL), also known as Haberland syndrome, is a rare, nonhereditary, nonprogressive congenital neurocutaneous syndrome with underlying ectodermal dysgenesis. The classic triad of this syndrome is central nervous system (CNS), ocular, and cutaneous involvement as unilateral lipomatous lesions of the scalp, neck, and face with ipsilateral brain anomalies and ipsilateral ocular choristoma. Herein, this study reports a case of a 2-year-old boy presented with status epilepticus for the first time.

Intratesticular lipoma in an elderly patient: A case report.

Introduction And Importance: Intratesticular lipoma is a rare benign tumor of the testis, with only a few cases documented in the literature. While extra testicular lipomas are more commonly observed, their presence within the testis is unusual. Due to the rarity of intratesticular lipomas, distinguishing them from malignant testicular tumors through non-invasive methods can be challenging, often requiring histopathological confirmation.

Resection of a cardiac lipoma and reconstruction wall of right atrium: A case report.

Rationale: Cardiac lipomas are known to cause functional disturbances and symptoms by compressing adjacent tissues or organs, leading to potential complications such as dyspnea, palpitations, and cardiac arrhythmias. We report a case of a 52-year-old female with a large, well-circumscribed lipoma in the right atrium. This rare condition required a comprehensive diagnostic approach and therapeutic strategy for effective management.

Colo-colic intussusception secondary to a giant lipoma: A case report.

Intussusception in adults is a rare condition often associated with a pathological lead point, which is frequently malignant but can occasionally be benign, such as colonic lipomas. We report the case of a 60-year-old male who presented with colicky abdominal pain, and a computed tomography (CT) revealed a colo-colic intussusception caused by a 6 cm lipoma in the transverse colon, accompanied by ischemic changes in the colonic mucosa. The patient underwent a right hemicolectomy, and histopathology confirmed the benign nature of the lesion.