2 results match your criteria: "Linyi City Lanshan District People's Hospital[Affiliation]"

Clinical significance of miR-142-3p in oral lichen planus and its regulatory role in keratinocyte proliferation.

Oral Surg Oral Med Oral Pathol Oral Radiol

October 2021

Department of Dermatology, Mengyin People's Hospital, Shandong, China. Electronic address:

Objective: Accumulating microRNAs (miRNAs) have been identified as aberrantly expressed in patients with oral lichen planus (OLP). This study aimed to investigate the role and underlying mechanism of miR-142-3p in OLP.

Study Design: Fifty-six patients with OLP and 44 control participants without OLP were recruited, and real-time quantitative reverse transcription polymerase chain reaction was used for the measurement of miR-142-3p.

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Introduction: This study investigated serum miR-221-3p levels in psoriatic patients and the characterization of serum miR-221-3p in keratinocyte inflammatory responses was further assessed.

Methods: qRT-PCR was used to detect the expression level of miR-221-3p in the serum of 46 patients with psoriasis and 42 healthy controls. The receiver operating characteristic curve evaluated the diagnostic ability of miR-221-3p in psoriasis.

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