2 results match your criteria: "Linfen Central Hospital Linfen[Affiliation]"
Construction of the ceRNA network in the progression of acute myocardial infarction.
Am J Cardiovasc Dis
December 2022
Department of Cardiovascular Surgery, Linfen Central Hospital Linfen, Shanxi, China.
Article Synopsis
- Acute myocardial infarction (AMI) is caused by sudden blockage of a coronary artery leading to heart tissue damage, with noncoding RNAs like circRNA, lncRNA, and miRNA playing significant roles in cardiovascular disease progression.
- Researchers analyzed three AMI datasets to identify differentially expressed genes, discovering 46 mRNAs, 65 miRNAs, and 5 circRNAs that were involved primarily in immune response pathways.
- The study highlights the circRNA-miRNA-mRNA regulatory network, particularly the roles of circRNA_023461 and circRNA_400027 in modulating miRNA-mRNA interactions, offering potential new perspectives for AMI treatment strategies.
lncRNA promotes atherosclerosis progression by targeting miR-382-5p.
Int J Clin Exp Pathol
September 2021
Department of Cardiology, Linfen Central Hospital Linfen, China.
Objective: Atherosclerosis is a key risk factor for the initiation of cardiovascular disease, which results in high morbidity and mortality. lncRNA taurine upregulated gene 1 () has been reported to participate in the development of atherosclerosis. Here, we aimed to investigate the interaction of and miR-382-5p in regulating atherosclerosis progression.
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