19 results match your criteria: "Limoges Hospital[Affiliation]"

Comparison of surgical management and outcomes of acute right colic and sigmoid diverticulitis: a French national retrospective cohort study.

Tech Coloproctol

November 2024

Department of Digestive, Oncological, Endocrine, Hepato-Biliary and Pancreatic Surgery, and Liver Transplantation, Colorectal Surgery Unit, Trousseau Hospital, University Hospital of Tours, Avenue de la République, 37044, Tours, France.

Background: Acute right colic diverticulitis (ARD) is less frequent in Western countries than acute sigmoid diverticulitis (ASD). We aimed to compare the management of ARD and ASD operated on in emergency.

Methods: All consecutive patients who had emergency surgery for ASD and ARD (2010-2021) were included in a retrospective, multicenter, cohort study.

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Article Synopsis
  • The study aims to assess how socioeconomic deprivation affects postoperative outcomes in patients who have undergone surgery for sigmoid diverticulitis (SD).
  • Conducted across 41 French hospitals from 2010 to 2021, researchers found that 20% of the 6,415 patients experienced severe complications within 90 days post-surgery.
  • Results indicated that higher levels of socioeconomic deprivation are linked to an increased risk of severe complications, even after adjusting for factors like age, sex, and surgery type.
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Aim: The aim of this work was to investigate the association between early postoperative anastomotic leakage or pelvic abscess (AL/PA) and symptomatic anastomotic stenosis (SAS) in patients after surgery for left colonic diverticulitis.

Method: This is a retrospective study based on a national cohort of diverticulitis surgery patients carried out by the Association Française de Chirurgie. The assessment was performed using path analyses.

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Risk factors for emergency surgery for diverticulitis: A retrospective multicentric French study at 41 hospitals.

Surgery

June 2024

Department of Digestive Surgery, University Hospital of Caen, France; Department of Research; CHU de Caen, ANTICIPE, Inserm Unity UMR 1086, France.

Background: The observed increase in the incidence of complicated diverticulitis may lead to the performance of more emergency surgeries. This study aimed to assess the rate and risk factors of emergency surgery for sigmoid diverticulitis.

Method: The primary outcomes were the rate of emergency surgery for sigmoid diverticulitis and its associated risk factors.

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Introduction: Implant exposure is the most frequent complication after evisceration or enucleation, and multiple surgical techniques for the management of orbital implant exposure. The goal of our study is to investigate the success rate and risk factors for failure of various surgical procedures.

Methods: This was a retrospective study performed at the University Hospital of Limoges.

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Background: In the decision to perform elective surgery, it is of great interest to have data about the outcomes of surgery to individualize patients who could safely undergo sigmoid resection. The aim of this study was to provide information on the outcomes of elective sigmoid resection for sigmoid diverticular disease (SDD) at a national level.

Methods: All consecutive patients who had elective surgery for SDD (2010-2021) were included in this retrospective, multicenter, cohort study.

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Article Synopsis
  • * Results showed significant improvements in key measures: time in range (TIR) increased by 9.1%, HbA1c decreased by 0.5%, and notable reductions in time spent below and above target levels.
  • * The majority of patients (92.7%) continued using the system, and more achieved glycemic goals after one year, although there were some reported cases of severe hypoglycemia and ketoacidosis.
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Impact of the first wave of COVID-19 epidemy on the surgical management of sigmoid diverticular disease in France: National French retrospective study.

Int J Colorectal Dis

December 2023

Department of Digestive, Oncological, Endocrine, Hepatobiliary and Liver Transplant, Trousseau Hospital, University Hospital of Tours, Avenue de la République, F37044 Tours, France.

Objective: To analyze the surgical management of sigmoid diverticular disease (SDD) before, during, and after the first containment rules (CR) for the first wave of COVID-19.

Methods: From the French Surgical Association multicenter series, this study included all patients operated on between January 2018 and September 2021. Three groups were compared: A (before CR period: 01/01/18-03/16/20), B (CR period: 03/17/20-05/03/20), and C (post CR period: 05/04/20-09/30/21).

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To investigate the relationship between the Short Physical Performance Battery (SPPB) and the Study of Osteoporotic Fractures (SOF) index. We present data from a cross-sectional survey conducted in Cameroon. Frailty was defined as an SOF index > 0.

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Statins in Primary Prevention in People Over 80 Years.

Am J Cardiol

January 2023

Inserm U1094, IRD U270, University of Limoges, CHU Limoges, EpiMaCT - Epidemiology of Chronic Diseases in Tropical Zone, U1094 Institute of Epidemiology and Tropical Neurology, Omega Health, Limoges, France; Division of Cardiology, Limoges Hospital Center, Limoges, France.

Article Synopsis
  • The management of cardiovascular diseases in individuals aged 80 and older requires tailored research instead of simply applying strategies from younger demographics.
  • Key issues to investigate include the role of cholesterol levels in mortality, the effectiveness of statins in preventing heart issues, and their safety for octogenarians.
  • Systematic reviews revealed mixed results: some studies found cholesterol levels didn’t correlate with higher cardiovascular risk, while most studies showed statins had little effect on reducing events, and side effects were notably more common in older patients.
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Background: A better understanding of pathological features and oncological survival in ypT0 rectal cancer after neoadjuvant chemoradiotherapy is required to improve patient selection criteria for rectal-preserving approach by local excision. Our aim was to define risk of lymph node metastasis and oncological outcomes in ypT0 rectal cancer after chemoradiotherapy and total mesorectal excision.

Methods: All consecutive patients who underwent total mesorectal excision for a nonmetastatic rectal adenocarcinoma classified ypT0 after neoadjuvant chemoradiotherapy, with or without locoregional lymph node involvement (ypN+ or ypN-), in 14 French academic centers between 2002 and 2015 were included.

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Chronic obstructive pulmonary disease associated with hypocomplementemic urticarial vasculitis.

J Allergy Clin Immunol Pract

October 2020

Department of Internal Medicine, Cochin Hospital, Paris, France; National Referral Centre for Systemic and Autoimmune Diseases, Cochin Hospital, Paris, France; Paris Descartes University, Université de Paris, Paris, France. Electronic address:

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Article Synopsis
  • Long-term outcome data indicate that velmanase alfa is effective for treating alpha-mannosidosis (AM), showing significant improvements in both biochemical and functional measures over up to 4 years of treatment.
  • Analysis involved 33 patients (14 adults, 19 children) who continued treatment after clinical trials, with key findings including substantial reductions in serum oligosaccharide levels and improved performance in a stair climb test.
  • Results suggest that early treatment during childhood leads to better functional outcomes, and no serious adverse events caused treatment discontinuation, highlighting the therapy's safety and effectiveness.
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Revisiting Vision Rehabilitation.

Front Syst Neurosci

November 2017

Department of Ophthalmology, Limoges Hospital, Limoges, France.

Low vision is a condition caused by eye or brain disease, in which visual acuity is 20/70 (3/10 or 6/18) or poorer in the better-seeing eye and cannot be corrected or improved with regular eyeglasses. It impacts personal ability to perform vision-dependent tasks as activities of daily living, walking, reading or using a computer. Rehabilitation is a multidisciplinary training dedicated to improve patients' functional abilities and quality of life.

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Purpose: Accurate and reproducible exophthalmometry is mandatory to diagnose and follow-up orbital patients, especially in Graves disease. However, many variations are described among the different commercially available exophthalmometers.

Methods: Sixty patients, who underwent a cerebral computed tomography (CT) scan, were included.

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Biallelic Mutations in LIPT2 Cause a Mitochondrial Lipoylation Defect Associated with Severe Neonatal Encephalopathy.

Am J Hum Genet

August 2017

Reference Center of Inherited Metabolic Diseases, University Paris Descartes, Hospital Necker Enfants Malades, APHP, 75015 Paris, France; UMR1163, University Paris Descartes, Sorbonne Paris Cité, Institut IMAGINE, 24 Boulevard du Montparnasse, 75015 Paris, France. Electronic address:

Lipoate serves as a cofactor for the glycine cleavage system (GCS) and four 2-oxoacid dehydrogenases functioning in energy metabolism (α-oxoglutarate dehydrogenase [α-KGDHc] and pyruvate dehydrogenase [PDHc]), or amino acid metabolism (branched-chain oxoacid dehydrogenase, 2-oxoadipate dehydrogenase). Mitochondrial lipoate synthesis involves three enzymatic steps catalyzed sequentially by lipoyl(octanoyl) transferase 2 (LIPT2), lipoic acid synthetase (LIAS), and lipoyltransferase 1 (LIPT1). Mutations in LIAS have been associated with nonketotic hyperglycinemia-like early-onset convulsions and encephalopathy combined with a defect in mitochondrial energy metabolism.

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There is a large body of research on discourse production in Alzheimer's disease (AD). Some studies have focused on pause production, revealing that patients make extensive use of pauses during speech. This has been attributed to lexical retrieval difficulties, but pausing may also reflect other forms of cognitive impairment as it increases with cognitive load.

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