Altered self-reported resting state mediates the effects of Mindfulness-Based Stress Reduction on mental health: a longitudinal path model analysis within a community-based randomized trial with 6-months follow-up.

Background: A large body of randomized controlled trials (RCTs) has shown that mindfulness-based interventions are effective for improving mental health, but research is lacking in regards to the mechanisms of change. We aimed to investigate the mediating effects of self-reported altered resting state of Mindfulness-Based Stress Reduction (MBSR) on mental health, when provided as a universal intervention in a real-life context.

Methods: Autoregressive path models with three time points of measurement, and contemporaneous and constant paths were used in an RCT.

Parental experiences of prenatal education when preparing for labor and birth of infant with a lethal diagnosis.

Aim: The aim of this study was to describe the unique experiences of parents facing a Life Limiting Fetal Conditions (LLFC) diagnosis, who chose to continue with their pregnancy, as they prepare for childbirth through individual and group prenatal education.

Design: A qualitative study.

Methods: We employed the phenomenological approach and the Colaizzi strategy to analyse semi-structured interviews.

Feasibility of a patient-oriented navigation programme for patients with lung cancer or stroke in Germany: Protocol of the CoreNAVI study.

Background: Patient navigation programmes were introduced in the United States and recently gained interest in Germany, where the health care system is fragmented. Navigation programmes aim to decrease barriers to care for patients with age-associated diseases and complex care paths. Here we describe a feasibility study to evaluate a patient-oriented navigation model that was developed in a first project phase by integrating data about barriers to care, vulnerable patient populations and existing support services.

Does coping with pain help the elderly with cardiovascular disease? The association of sense of coherence, spiritual well-being and self-compassion with quality of life through the mediating role of pain self-efficacy.

Background: Population ageing is considered one of the biggest challenges facing the world, and the status of the elderly in society and their quality of life (QOL) have proved to be a concern in professional and scientific research circles. As a result, the current study sought to investigate the role of pain self-efficacy (PSE) as a moderator in the relationship between sense of coherence (SOC), spiritual well-being, and self-compassion with QOL in Iranian elderly with cardiovascular disease (CVD).

Method: This was a correlational study of the path analysis type.

Digital Citizenship and Life Satisfaction in South Korean Adolescents: The Moderated Mediation Effect of Poverty.

This study examined the moderated mediation effect of poverty on the paths between enactive mastery experience in digital life and life satisfaction mediated by digital citizenship and digital life among Korean adolescents using structural equation modelling. This cross-sectional study involved a secondary data analysis of 2020 national data in The Report on the Digital Divide provided by the National Information Society Agency (NIA) of Korea. Data from 1084 Korean adolescents were analyzed using IBM SPSS Statistics for Windows, version 26.

Dual-functional metalenses for the polarization-controlled generation of focalized vector beams in the telecom infrared.

The availability of static tiny optical devices is mandatory to reduce the complexity of optical paths that typically use dynamic optical components and/or many standard elements for the generation of complex states of light, leading to unprecedented levels of miniaturization and compactness of optical systems. In particular, the design of flat and integrated optical elements capable of multiple vector beams generation with high resolution in the visible and infrared range is very attractive in many fields, from life science to information and communication technology. In this regard, we propose dual-functional transmission dielectric metalenses that act simultaneously on the dynamic and geometric phases in order to manipulate independently right-handed and left-handed circularly polarized states of light and generate focused vector beams in a compact and versatile way.

Emergent multipath COVID-19 specimen collection problem with green corridor through variable length GA.

The COVID-19 pandemic has spread worldwide exponentially. Typically, for testing, a provincial main government hospital cum testing center collects patients' specimens from remote health centers in the minimum possible time, satisfying the 'false negativity' constraint of the first collected specimen. With infrastructural developments throughout the world, multiple paths are available for transportation between two cities.

Efficient lithium extraction using redox-active Prussian blue nanoparticles-anchored activated carbon intercalation electrodes via membrane capacitive deionization.

Global demand for lithium (Li) resources has dramatically increased due to the demand for clean energy, especially the large-scale usage of lithium-ion batteries in electric vehicles. Membrane capacitive deionization (MCDI) is an energy and cost-efficient electrochemical technology at the forefront of Li extraction from natural resources such as brine and seawater. In this study, we designed high-performance MCDI electrodes by compositing Li intercalation redox-active Prussian blue (PB) nanoparticles with highly conductive porous activated carbon (AC) matrix for the selective extraction of Li.

Event-related potential (ERP) markers of 22q11.2 deletion syndrome and associated psychosis.

22q11.2 deletion syndrome (22q11.2DS) is a multisystemic disorder characterized by a wide range of clinical features, ranging from life-threatening to less severe conditions.

Life design facing the fertility gap: promoting gender equity to give women and men the freedom of a mindful life planning.

Nowadays, society is characterized by enormous and rapid changes, erratic careers, gender discrimination, injustices, and inequities. Discrimination includes professional and educational segregation, the gender pay gap, stereotypical gender roles, and social expectations. In this context, phenomena called low fertility and fertility gap are increasing.

Pathways Through Which Experience in Treatment Decision-Making Affects Health-Related Quality of Life in People with Chronic Conditions.

Patient engagement in treatment decision-making is essential to improve the health-related quality of life (HRQoL) of patients affected by chronic diseases. However, research on how decision-making patterns influence HRQoL is limited. This study investigated the paths linking patient experience in decision-making to HRQoL through healthcare accessibility and physical activity among a representative sample of adults with chronic diseases.

Stochastic Propagation of Fatigue Cracks in Welded Joints of Steel Bridge Decks under Simulated Traffic Loading.

The fatigue cracking of orthotropic steel bridge decks (OSDs) is a difficult problem that hinders the development of steel structures. The most important reasons for the occurrence of fatigue cracking are steadily growing traffic loads and unavoidable truck overloading. Stochastic traffic loading leads to the random propagation behavior of fatigue cracks, which increases the difficulty of the fatigue life evaluations of OSDs.

Delapré Walk project: Are signposted walking routes an effective intervention to increase engagement in urban parks? -Natural experimental study.

Spatial education interventions in the built environment may increase engagement with urban greenspace. This research was a natural experimental study with mixed-method evaluation and repeated cross-sectional design. Twenty-four directional wayfinding signs were installed within an urban park to create a 3 km signposted walking route through the park's amenities in a clockwise direction.

NoRCEL's Engagement in Africa: The AstroScience Exploration Network (ASEN).

The AstroScience Exploration Network (ASEN) is the latest innovative initiative from the Network of Researchers on the Chemical Emergence of Life (NoRCEL). Materializing on the vibrancy of the African continent, recognizing its people as a key asset, and building on specific strategic advantages, ASEN will funnel the appetite for scientific knowledge through an educational hub that paves the way for the Global South to come to the fore in new global endeavors and will eventually help build a variety of career paths in a diversifying economy.

Point cloud completion in challenging indoor scenarios with human motion.

Combining and completing point cloud data from two or more sensors with arbitrarily relative perspectives in a dynamic, cluttered, and complex environment is challenging, especially when the two sensors have significant perspective differences while the large overlap ratio and feature-rich scene cannot be guaranteed. We create a novel approach targeting this challenging scenario by registering two camera captures in a time series with unknown perspectives and human movements to easily use our system in a real-life scene. In our approach, we first reduce the six unknowns of 3D point cloud completion to three by aligning the ground planes found by our previous perspective-independent 3D ground plane estimation algorithm.

Bioprocessing and the Production of Antiviral Biologics in the Prevention and Treatment of Viral Infectious Disease.

Emerging, re-emerging and zoonotic viral pathogens represent a serious threat to human health, resulting in morbidity, mortality and potentially economic instability at a global scale. Certainly, the recent emergence of the novel SARS-CoV-2 virus (and its variants) highlighted the impact of such pathogens, with the pandemic creating unprecedented and continued demands for the accelerated production of antiviral therapeutics. With limited effective small molecule therapies available for metaphylaxis, vaccination programs have been the mainstay against virulent viral species.

The relationship between social determinants of health and fear of contracting infectious diseases in pregnant women presenting to health centers in Kashan, Iran: a path analysis study.

Introduction: Pregnancy is one of the most critical times in a woman's life that is accompanied by a lot of worry, fear, and stress for the mother, and fear of contracting diseases and losing the children are among the most important of them. The present study investigated the relationship between the social determinants of health and fear of contracting infectious diseases in pregnant women using path analysis.

Methods: This cross-sectional study was conducted on 330 pregnant Iranian women in Kashan from September 21th, 2021, to May 25th, 2022, using a multi-stage method.

Biased activation of the receptor tyrosine kinase HER2.

HER2 belongs to the ErbB sub-family of receptor tyrosine kinases and regulates cellular proliferation and growth. Different from other ErbB receptors, HER2 has no known ligand. Activation occurs through heterodimerization with other ErbB receptors and their cognate ligands.

Exploring strengths, psychological functioning and youth victimization among American Indians and Alaska Natives in four southern states.

Background: Identifying factors that support healthy psychological functioning after experiencing violence or other adversities in youth can lead to better prevention and intervention efforts. This is particularly important among communities with disproportionately high rates of adversity resulting from legacies of social and political injustices, such as American Indian and Alaska Native populations.

Methods: Data were pooled from four studies in the southern U.

The Neglected Role of Domestic Migration on Family Patterns in Latin America and the Caribbean, 1950-2000.

Urbanization has played a key role in shaping twentieth-century demographic changes in Latin America and the Caribbean (LACar). As a result, scholarly research on domestic migration and the family has primarily focused on fertility differentials by migration status in urban areas, finding a robust negative correlation between internal migration and fertility. This research has overlooked how this relationship varies across types of migration flows other than rural-to-urban migration and by women's age at migration and social class.

Integrating media content analysis, reception analysis, and media effects studies.

Every day, the world of media is at our fingertips, whether it is watching movies, listening to the radio, or browsing online media. On average, people spend over 8 h per day consuming messages from the mass media, amounting to a total lifetime dose of more than 20 years in which conceptual content stimulates our brains. Effects from this flood of information range from short-term attention bursts (e.

Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer.

Bladder cancer cells can acquire persistent infection of oncolytic Newcastle disease virus (NDV) but the molecular mechanism(s) remain unelucidated. This poses a major barrier to the effective clinical translation of oncolytic NDV virotherapy of cancers. To improve our understanding of the molecular mechanism(s) associated with the development of NDV persistent infection in bladder cancer, we used mRNA expression profiles of persistently infected bladder cancer cells to construct PPI networks.

Polyvictimization, polystrengths, and their contribution to subjective well-being and posttraumatic growth.

Objective: The negative biopsychosocial outcomes associated with exposure to victimization are well-known, however, limited research has examined the protective factors that can enhance well-being and growth following polyvictimization from in-person and digital sources. This study examines the contribution of adversities and a range of psychological and social strengths on perceptions of subjective well-being and posttraumatic growth (PTG).

Method: A sample of 478 individuals aged 12-75 (57.

Multidimensional single-cell analysis of human peripheral blood reveals characteristic features of the immune system landscape in aging and frailty.

Frailty is an intermediate status of the human aging process, associated with decompensated homeostasis and death. The immune phenotype of frailty and its underlying cellular and molecular processes remain poorly understood. We profiled 114,467 immune cells from cord blood, young adults and healthy and frail old adults using single-cell RNA and TCR sequencing.