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Dead or alive? New confirmatory test using quantitative analysis of computed tomographic angiography.
J Trauma Acute Care Surg
December 2015
From the Departments of Surgery (L.P.S.-K., W.J.B., F.E.D.), and Radiology (D.A.P., P.M.B.), and The Curtis and Elizabeth Anderson Cancer Institute (E.J.C.), Memorial University Medical Center; Department of Surgery (W.J.B., F.E.D.), Mercer University School of Medicine; and Neurologic Institute of Savannah & Center for Spine (J.U.H.), Savannah; and Department of Surgery (C.M.M.), Liberty Regional Medical Center, Hinesville, Georgia.
Article Synopsis
- The study compares the effectiveness of Computed Tomographic Angiography (CTA) and Nuclear Medicine Perfusion Test (NMPT) in diagnosing brain death (BD), involving 60 clinically determined BD patients and a control group of 20.
- Results showed that 88% of BD patients had no cerebral blood flow (CBF) on NMPT, whereas only 50% showed the same on CTA, leading to the identification of three distinct groups based on blood flow outcomes from both tests.
- The researchers recommend a threshold of Hounsfield units less than 80 in specific arteries on CTA to confirm BD, achieving a high sensitivity of 97% and specificity of 100% in identifying a lack of