Serine/threonine protein kinase mediates rifampicin resistance in through interacting with ribosomal protein RpsD and affecting antioxidant capacity.

Unlabelled: Brucellosis, a zoonotic disease, has re-emerged in both humans and animals, causing significant economic losses globally. Recently, an increasing number of rifampicin-resistant strains have been isolated worldwide without detectable mutations in known antibiotic resistance genes. Here, this study identified the deletion of serine/threonine protein kinase (STPK) gene in as an efficient trigger for rifampicin resistance using bioinformatics predictions, a transposon mutant library, and gene mutation strains.

The effects of body dissatisfaction, sleep duration, and exercise habits on the mental health of university students in southern China during COVID-19.

Following the outbreak of COVID-19 at the end of 2019, universities around the world adopted a closed management model and various restrictive measures intended to reduce human contact and control the spread of the disease. Such measures have had a profound impact on university students, with a marked increase in depression-related psychological disorders. However, little is known about the specific status and factors influencing the impact of the pandemic on student mental health.

The effects of body dissatisfaction and depression levels on the dietary habits of university students in southern China during COVID-19.

Introduction: The novel coronavirus disease of 2019 has impacted people's lives greatly. The spread of the pandemic has restricted many everyday social lives. Some studies have shown that strict risk control during the pandemic threatens people's mental health and eating habits.

The associations between body dissatisfaction, exercise intensity, sleep quality, and depression in university students in southern China.

Background: In recent years, depression in early adulthood has become an urgent global public health concern. The university years mark a transitional period from adolescence to adulthood. Young people are required to face academic and life pressures independently, which increases the risk of mental health problems in university.

Nutritional status, food consumption, lifestyle, and physical fitness in rural and urban elementary school children in Northeast China.

Childhood obesity is observed not only in developed countries but also in some developing countries in Asia, where low physical activity and poor physical fitness have been reported. The primary goal of weight loss is to reduce body fat mass, thereby reducing the risk of metabolic syndrome. Unfortunately, a concomitant decrease in lean mass, including muscle mass, is often observed when weight is lost.

Will the zero-margin drug policy reduce the economic burden of stroke patients in China?

Background: China is facing a more severe stroke challenge. In 2017, China fully implemented the zero-margin drug policy (ZMDP), cancelling 15% of drug markups in public hospitals. Based on the "System of Health Accounts 2011" (SHA 2011), this paper explores the changes in the economic burden of stroke in China after implementing ZMDP to provide an accurate reference for policymakers.

Vortex-assisted natural deep eutectic solvent dispersive liquid-liquid microextraction based on the solidification of a floating organic drop for the determination of benzoic acid and sorbic acid in condiments.

A simple, inexpensive, reliable and environmentally friendly method based on vortex-assisted dispersive liquid-liquid microextraction combined with solidification of a floating organic drop (VA-DLLME-SFO) followed by high performance liquid chromatography with a diode array detector (HPLC-DAD) was developed to determine benzoic acid (BA) and sorbic acid (SA) in ketchup and powder bags of instant noodles. Hydrophobic natural deep eutectic solvents (NADESs), as the microextraction solvent, were prepared with ternary components. Acetic acid can reduce the viscosity of hydrophobic NADESs and vortex can promote the dispersion of NADESs in aqueous solvents.

Whole-genome sequencing of rough in China provides insights into its genetic features.

spp. can cause the zoonosis brucellosis, which affects public health and safety and even economic development. has a smooth phenotype, while 28 isolates had a rough phenotype in 2018.

Epidemiological and genetic investigation of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus.

Background: To analyze and discuss the transmission route of a cluster of cases of severe fever with thrombocytopenia syndrome bunyavirus (SFTSV).

Method: We performed an epidemiological investigation and a genetic analysis of patients with severe fever with thrombocytopenia syndrome (SFTS) caused by SFTSV, their close contacts and the surrounding population.

Results: We found that all patients had contact with the blood of the first patient.

[Influenza surveillance from 1999 to 2005 in Liaoning regions].

Objective: To investigate the prevalence and subtypes of influenza viruses in Liaoning regions from November 1999 to March 2005.

Methods: Influenza virus was isolated by embryonated eggs together with cell culture and subtypes, identified by HI test.

Results: During the study in 1999 - 2005, a total number of 2713 swab specimens were collected in different cities in Liaoning regions in which 188 strains were identified for influenza viruses with an average rate as 7.