8-O-Ethyl-yunaconitine from the roots of Aconitum carmichaeli Debx.

THE TITLE COMPOUND [SYSTEMATIC NAME: (1α,3α,6α,8β,13β,14α,16β)-20-ethyl-8-eth-oxy-3,13-dihy-droxy-1,6,16-trimeth-oxy-4-(meth-oxy-meth-yl)aconitan-14-yl 4-meth-oxy-benzoate], C(35)H(51)NO(10), was isolated from roots of Aconitum carmichaeli Debx., which is a typical C(19)-diterpenoid alkaloid. The mol-ecule has an aconitane carbon skeleton with four six-membered rings and two five-membered rings.

Clinical Outcomes After Computer-assisted Versus Conventional Total Knee Arthroplasty.

The purpose of this study was to determine whether the use of computer-assisted surgery can improve the clinical results in total knee arthroplasty (TKA) compared with conventional methods of TKA.A literature search of PubMed (1966 to August 2011), CENTRAL (Cochrane Controlled Trials Register; issue 3, 2011), and EMBASE (1984 to August 2011) was conducted. Randomized, controlled trials detecting the clinical outcomes of TKA with or without the use of computer-assisted surgery were identified.

Purification and anticancer activity investigation of pentacyclic triterpenoids from the leaves of Sinojackia sarcocarpa L.Q. Luo by high-speed counter-current chromatography.

Sinojackia sarcocarpa L.Q. Luo has high aesthetic value, which is clinically used to treat diseases such as the variations of arthritis, thromboangiitis obliterans, angina pectoris as well as many other diseases.

Preparation and mechanical property of poly(ε-caprolactone)-matrix composites containing nano-apatite fillers modified by silane coupling agents.

This study aims to improve the tensile strength and elastic modulus of nano-apatite/poly(ε-caprolactone) composites by silane-modification of the nano-apatite fillers. Three silane coupling agents were used to modify the surfaces of nano-apatite particles and composites of silanized apatite and PCL were prepared by a technique incorporating solvent dispersion, melting-blend and hot-pressing. The results showed that the silane coupling agents successfully modified the surfaces of nano-apatite fillers, and the crystallization temperatures of the silanized apatite/PCL composites were the higher than that of the non-silanized control material, although the melting temperature of the composites remained almost unaffected by silanization.

Bonvalotidine A acetone solvate from Delphinium bonvalotii Franch.

5,6β-dihy-droxy-1α,14α,16β-trimeth-oxy-4-methyl-7β,8-methyl-enedi-oxy-20-ethyl-aconitan-6-yl acetate acetone monosolvate), C(27)H(41)NO(8)·C(3)H(6)O, was isolated from Delphinium bonvalotii Franch, and is a typical C(19)-diterpenoid alkaloid. The mol-ecule has a lycoctonine carbon skeleton with four six-membered rings and three five-membered rings. Three six-membered rings adopt the chair conformations while the fourth adopts a boat conformation, while the five-membered rings have the envelope conformations.

[Selection of mobile phases for the determination of gamma-schisandrin and multi-active constituents in Schisandra chinensis and its preparations by high performance liquid chromatography].

The systems of mobile phase for the determination of gamma-schisandrin in Schisandra chinensis and its preparations were developed by high performance liquid chromatography (HPLC). The separation was performed on a Shim-pack VP-ODS column (250 mm x 4.6 mm, 5 microm) at 30 degrees C, the detection wavelength was set at 285 nm and the flow rate was 1.

(1β,2α,3α,7α,11α,13β)-1,3,7,11-Tetra-acet-oxy-2,13-bis-(benz-yloxy)-21-methyl-19,21-secohetisan-19-al hemi-hydrate.

In the crystal structure of the title compound, C(43)H(46)NO(13)·0.5H(2)O, the mol-ecule assumes a U-shaped conformation, the terminal benzene rings being approximately parallel and partially overlapped with each other. The mol-ecule contains eight alicyclic and heterocyclic rings.

The effect of surfactant micelles on the dissociation constants and transition points and transition intervals of acid-base indicators.

The effects of cetyltrimethylammonium (CTAB), sodiumdodecylsulfate (SDS) and pol(oxyethylene)(9.5)p-(1,1,3,3-tetramethyl; Triton X-100) on the dissociation constants, transition points and transition intervals of thymol blue and bromothymol blue were studied. The experimental results indicated that surfactant micelles remarkably affected dissociation constants, transition points and transition intervals of the acid-base indicators, and the application ranges of acid-base indicators became wider and the titration accuracy increased when an appropriate surfactant micellar solution was chosen as a titration medium.

Anticancer activity and quantitative analysis of flavone of Cirsium japonicum DC.

Cirsium japonicum DC, a traditional Chinese medicine, has been widely used as an antihemorrhagic and diuretic agent. The objective of this study was to perform quantitative analysis of flavone by reversed-phase HPLC and examine the anticancer activity of C. japonicum DC in the S180 and H22 mice.

[Polymorphisms in semilate indica hybrid rice as revealed by AFLPs].

The polymorphisms were analyzed in 15 semilate indica parental materials with AFLPs. The genetic distances between parental materials were small with an average of 0.2033, ranged from 0.

[Comparison of total saponin content in three wild species of Gynostemma on Mount Emei].

Analysed by TLC and spectrometry, the content of the total saponin in three wild species of Gynostemma on Mount Emei is found to be the highest in July and to be the lowest in the seedling stage. Among the three, the content of the total saponin in Gynostemma pentaphyllum is the highest, that in Gynostemma pubescens lower and that in Gynostemma longipes the lowest.

Developmental exposure to polychlorinated biphenyls affects sexual behavior of rats.

Polychlorinated biphenyls (PCBs) are persistent environmental contaminants that have the potential to disrupt reproduction through a variety of different pathways. In the present study, we investigated the effects of fetal and lactational PCB exposure on reproductive behavior in male and female laboratory rats. These pregnant rats were injected daily with either 2,4,2',4'-tetrachlorobiphenyl (PCB 47) at the dosage of 1 or 20 mg/kg body weight or 3,4,3',4'-tetrachlorobiphenyl (PCB 77) at the dosage of 0.