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5,337 results match your criteria: "Lentigo"
Arch Dermatol Res
December 2024
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 530 East 73rd Street, New York, NY, 10021, USA.
Melanoma of the lentigo maligna (LM) type is most commonly located on the head and neck region. This subtype of melanoma poses surgical challenges due to its location on anatomically sensitive areas and frequent presence of subclinical extension. To analyze the reconstruction patterns of LM patients undergoing margin-controlled surgery.
View Article and Find Full Text PDFBr J Dermatol
December 2024
Department of Population Health, QIMR Berghofer Medical Research Institute, Queensland, Australia.
Background: Understanding the factors influencing age at melanoma diagnosis by sex and anatomic site is crucial for developing effective prevention and early detection strategies. While previous research has highlighted sex-based differences in melanoma incidence by age and anatomic distribution, the underlying mechanisms remain unclear. We aimed to investigate sex-specific patterns in melanoma age at diagnosis across different anatomic sites and thickness categories, considering the potential influence of disease progression and detection rates.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
December 2024
Dermatology Department, Norfolk & Norwich University Hospital, Norwich, UK.
JAAD Int
February 2025
NHMRC Clinical Trials Centre, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia.
Background: Factors associated with nonadherence to guideline-recommended complete excision of suspicious cutaneous lesions are unclear.
Objective: The purpose of this study was to analyze patient, melanoma, and clinician factors associated with initial diagnostic biopsy type and determine whether unwarranted variation from guidelines occurred.
Methods: This population-based, cohort study involved the analysis of data from questionnaires completed by clinicians who managed patients with newly diagnosed, histopathologically confirmed primary invasive cutaneous melanomas reported to the New South Wales Cancer Registry between 2006 and 2007.
Free Radic Biol Med
February 2025
Department of Dermatology, Huashan Hospital, Fudan University, No.12 Wulumuqi Zhong Road, Shanghai 200040, PR China. Electronic address:
Dermatol Pract Concept
October 2024
Dermatology Service, Miguel Servet University Hospital, IIS Aragón, Zaragoza, Spain.
Dermatol Pract Concept
October 2024
Dermatology Unit, IRCCS Humanitas Research Hospital, Rozzano (MI), Italy.
J Am Acad Dermatol
December 2024
Division of Dermatology, Dell Medical School at the University of Texas, Austin, Texas.
Zootaxa
May 2024
12 Crescent Grove; London SW4 7AH; UK.
The systematics of 37 new species of Devonian Harpetidae from the central and eastern Anti-Atlas Mountains, Morocco, are described. The new material comes from the Dra-Tafilalet region and the province of Tata. A cladistic study was undertaken involving 138 taxa with the objective of assigning the new taxa to the appropriate genera, which are, as far as possible, monophyletic.
View Article and Find Full Text PDFBackground: Lentigo maligna (LM), a type of melanoma in situ (MIS), usually develops on sun-damaged skin in the elderly. If left untreated, it may advance to the point of dermal invasion, developing into lentigo maligna melanoma (LMM). While surgeons have achieved robust clinical outcomes for LM treated with Mohs micrographic surgery (MMS), performing this treatment for LMM remains controversial and is not standard amongst all Mohs surgeons.
View Article and Find Full Text PDFDermatol Surg
December 2024
Department of Oral and Maxillofacial Surgery, University Hospital of Saint-Etienne, France.
J Gastroenterol Hepatol
February 2025
Division of Gastroenterology, Department of Medicine, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Dermatol Ther (Heidelb)
January 2025
Department of Clinical and Experimental Medicine, Section of Dermatology, University of Messina, Messina, Italy.
Background: Tirbanibulin 1% ointment has been licensed to treat non-hyperkeratotic actinic keratosis (AK) on the face and scalp in adults. Recent evidence suggests that, besides the antineoplastic effect, tirbanibulin may also confer substantial cosmetic benefits to patients.
Methods: We report a single-center retrospective study of patients affected by solar lentigines (SLs) and AKs in the context of field cancerization treated with tirbanibulin 1% ointment.
Stem Cell Res
December 2024
Department of Gastroenterology, The Second Hospital of Shandong University, Jinan, China. Electronic address:
We report the derivation of an induced pluripotent stem cell (iPSC) line, designated TSHSUi002-A, from a patient with Peutz-Jeghers syndrome carrying a heterozygous c.909C>G mutation in the STK11 gene. The iPSCs were generated through the reprogramming of peripheral blood mononuclear cells using a non-integrating method involving episomal vectors expressing OCT4, SOX2, KLF4, BCL-XL, and c-MYC.
View Article and Find Full Text PDFDiagnostics (Basel)
November 2024
Ophthalmology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Lentigo maligna (LM) often poses a diagnostic challenge due to its clinical and dermoscopic mimicry of benign lesions, leading to delayed diagnosis. Focal areas of reticular disruption have been described as one of the earliest dermoscopic signs observed. To describe a novel dermoscopic sign in LM, namely the presence of a parallel pigmented network.
View Article and Find Full Text PDFAustralas J Dermatol
February 2025
Mayne Academy of General Practice, Medical School, the University of Queensland, Brisbane, Queensland, Australia.
Melanomas on the dorsum of the hand are exceedingly rare, with limited documentation in medical literature. This report presents seven cases of dorsal hand and finger melanomas, encompassing patients from Australia, New Zealand and Turkey, predominantly women with a mean age of 53 years. The majority were invasive, with a mean Breslow thickness of 1.
View Article and Find Full Text PDFActas Dermosifiliogr
February 2025
Servicio de Dermatología, Hospital Universitario de Navarra, Pamplona, Navarra, Spain.
J Eur Acad Dermatol Venereol
March 2025
Department of Dermatology, Escuela de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Background: Melanoma of the lentigo maligna (LM) type and its invasive counterpart, lentigo maligna melanoma (LMM), occur in chronically sun-damaged skin and tend to have subclinical extension that makes presurgical margin mapping challenging. Reflectance confocal microscopy (RCM) is a non-invasive imaging modality that enables in vivo visualization of the skin at the cellular level, allowing for adequate estimation of LM/LMM margins.
Objectives: We aimed to perform a systematic review and meta-analysis evaluating RCM's performance compared with histopathology in margin mapping of LM/LMM.
Clin J Gastroenterol
February 2025
Department of Gastroenterology and Hematology, Hirosaki University Graduate School of Medicine, Aomori, 036-8562, Japan.
A solitary Peutz-Jeghers (PJ) polyp is a rare hamartomatous lesion without an associated PJ syndrome. However, little is known regarding malignancy arising in solitary PJ polyps. Here, we report a case of a solitary colonic PJ polyp with focal dysplasia.
View Article and Find Full Text PDFJ Eur Acad Dermatol Venereol
March 2025
Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Background: Lentigo maligna (LM) is a growing problem worldwide and the main type of melanoma in situ in some Caucasian populations. It presents as a spectrum from atypical intraepidermal melanocytic proliferation (AIMP) to invasive lentigo maligna melanoma (LMM). Accurate diagnosis and staging are crucial for determining appropriate management strategies.
View Article and Find Full Text PDFZhongguo Dang Dai Er Ke Za Zhi
October 2024
Department of Digestive Nutrition, Hunan Children's Hospital, Changsha 410007, China.
Bioengineering (Basel)
October 2024
Dermatology Unit, Department of Medicine, Surgery and Neuroscience, University of Siena, 53100 Siena, Italy.
Br J Dermatol
January 2025
Division of Dermatologic Surgery, Mayo Clinic, Rochester, MN, USA.
Clin Exp Dermatol
February 2025
Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Background: Melanoma in young adults significantly impacts the survival of individuals in this age group. There are few studies that analyse melanoma characteristics in young patients.
Objectives: To describe the epidemiological, clinical and histological characteristics of melanoma in young adults and the temporal trends in these characteristics in recent decades.