Laccase-Enzyme Treated Flax Fibre for Use in Natural Fibre Epoxy Composites.

Natural fibres have a high potential as reinforcement of polymer matrices, as they combine a high specific strength and modulus with sustainable production and reasonable prices. Modifying the fibre surface is a common method to increase the adhesion and thereby enhance the mechanical properties of composites. In this study, a novel sustainable surface treatment is presented: the fungal enzyme laccase was utilised with the aim of covalently binding the coupling agent dopamine to flax fibre surfaces.

Experimental Study on Concrete under Combined FRP-Steel Confinement.

The confinement of reinforced concrete (RC) compression members by fiber-reinforced polymers (FRPs) is an effective measure for the strengthening and retrofitting of existing structures. Thus far, extensive research on the stress-strain behavior and ultimate limit state design of FRP-confined concrete has been conducted, leading to various design models. However, these models are significantly different when compared to one another.

An exploratory randomized controlled trial comparing wood-composite and synthetic fibreglass splint systems for the immobilization of paediatric upper limb fractures.

Aims: This exploratory randomized controlled trial (RCT) aimed to determine the splint-related outcomes when using the novel biodegradable wood-composite splint (Woodcast) compared to standard synthetic fibreglass (Dynacast) for the immobilization of undisplaced upper limb fractures in children.

Methods: An exploratory RCT was performed at a tertiary paediatric referral hospital between 1 June 2018 and 30 September 2019. The intention-to-treat population consisted of 170 patients (mean age 8.

"Movement-enhancing footpaths" - A natural experiment on street design and physical activity in children in a deprived district of Leipzig, Germany.

Despite the beneficial effects of physical activity (PA), only 26% of children in Germany meet the WHO's recommendations. Because active play contributes to PA and is accepted by families, the creation of "playable" environments could promote PA. This study is a natural experiment that was conducted to investigate whether slight changes in the physical environment can increase PA in children.

Associations of Green Spaces and Streets in the Living Environment with Outdoor Activity, Media Use, Overweight/Obesity and Emotional Wellbeing in Children and Adolescents.

Aspects of the living environment can affect health and wellbeing of children and adolescents. Whereas most previous studies assessed the more distant residential urban environment, less is known on possible effects of the close environment. The present study investigated associations of the proportion of streets and green spaces in the immediate urban living environment (50, 100 and 400 m around the home) with media use, outdoor activity, overweight/obesity and emotional problems in two samples of younger (age 3-10, = 395) and older children (age 10-19, = 405).

Experimental and Numerical Impact Analysis of Automotive Bumper Brackets Made of 2D Triaxially Braided CFRP Composites.

The impact behavior of carbon fiber epoxy bumper brackets reinforced with 2D biaxial and 2D triaxial braids was experimentally and numerically analyzed. For this purpose, a phenomenological damage model was modified and implemented as a user material in ABAQUS. It was hypothesized that all input parameters could be determined from a suitable high-speed test program.

The Impact of Draping Effects on the Stiffness and Failure Behavior of Unidirectional Non-Crimp Fabric Fiber Reinforced Composites.

Unidirectional non-crimp fabrics (UD-NCF) are often used to exploit the lightweight potential of continuous fiber reinforced plastics (CoFRP). During the draping process, the UD-NCF fabric can undergo large deformations that alter the local fiber orientation, the local fiber volume content (FVC) and create local fiber waviness. Especially the FVC is affected and has a large impact on the mechanical properties.

Correlia: an ImageJ plug-in to co-register and visualise multimodal correlative micrographs.

The correlation of different microscopic imaging techniques alongside with microanalytical methods is crucial to better understand biological processes on a subcellular level. For that, micrographs and chemical maps exhibiting both, very different spatial resolution and field-of-view but also a highly multimodal content has to be co-registered. We developed the ImageJ/Fiji plug-in Correlia that provides an environment for handling multimodal correlative microscopy data.

An image dataset related to automated macrophage detection in immunostained lymphoma tissue samples.

Background: We present an image dataset related to automated segmentation and counting of macrophages in diffuse large B-cell lymphoma (DLBCL) tissue sections. For the classification of DLBCL subtypes, as well as for providing a prognosis of the clinical outcome, the analysis of the tumor microenvironment and, particularly, of the different types and functions of tumor-associated macrophages is indispensable. Until now, however, most information about macrophages has been obtained either in a completely indirect way by gene expression profiling or by manual counts in immunohistochemically (IHC) fluorescence-stained tissue samples while automated recognition of single IHC stained macrophages remains a difficult task.

Multi-scale imaging and analysis identify pan-embryo cell dynamics of germlayer formation in zebrafish.

The coordination of cell movements across spatio-temporal scales ensures precise positioning of organs during vertebrate gastrulation. Mechanisms governing such morphogenetic movements have been studied only within a local region, a single germlayer or in whole embryos without cell identity. Scale-bridging imaging and automated analysis of cell dynamics are needed for a deeper understanding of tissue formation during gastrulation.

Anodal Transcranial Direct Current Stimulation Over S1 Differentially Modulates Proprioceptive Accuracy in Young and Old Adults.

Background: Proprioception is a prerequisite for successful motor control but declines throughout the lifespan. Brain stimulation techniques such as anodal transcranial direct current stimulation (a-tDCS) are capable of enhancing sensorimotor performance across different tasks and age groups. Despite such growing evidence for a restorative potential of tDCS, its impact on proprioceptive accuracy has not been studied in detail yet.

Assessment of Standards and Codes Dedicated to CFRP Confinement of RC Columns.

Reinforced concrete (RC) columns are often placed under confinement to increase their strength and ductility. Carbon fiber reinforced polymer (CFRP) materials have recently been recognized as favorable confinement systems. At present, a number of national standards and codes dedicated to the design of concrete components strengthened with CFRP in general and CFRP confinement in particular are available.

Automated macrophage counting in DLBCL tissue samples: a ROF filter based approach.

Background: For analysis of the tumor microenvironment in diffuse large B-cell lymphoma (DLBCL) tissue samples, it is desirable to obtain information about counts and distribution of different macrophage subtypes. Until now, macrophage counts are mostly inferred from gene expression analysis of whole tissue sections, providing only indirect information. Direct analysis of immunohistochemically (IHC) fluorescence stained tissue samples is confronted with several difficulties, e.

Radial profile detection of multiple spherical particles in contact with interacting surfaces.

Adhesive interactions of soft materials play an important role in nature and technology. Interaction energies can be quantified by determining contact areas of deformable microparticles with the help of reflection interference contrast microscopy (RICM). For high throughput screening of adhesive interactions, a method to automatically evaluate large amounts of interacting microparticles was developed.

Properties of network structures, structure coefficients, and benefit-to-cost ratios.

In structured populations the spatial arrangement of cooperators and defectors on the interaction graph together with the structure of the graph itself determines the game dynamics and particularly whether or not fixation of cooperation (or defection) is favored. For networks described by regular graphs and for a single cooperator (and a single defector) the question of fixation can be addressed by a single parameter, the structure coefficient. This quantity is invariant with respect to the location of the cooperator on the graph and also does not vary over different networks.

Fixation properties of multiple cooperator configurations on regular graphs.

Whether or not cooperation is favored in evolutionary games on graphs depends on the population structure and spatial properties of the interaction network. The population structure can be expressed as configurations. Such configurations extend scenarios with a single cooperator among defectors to any number of cooperators and any arrangement of cooperators and defectors on the network.

Semi-automated generation of individual computational models of the human head and torso from MR images.

Purpose: Simulating the interaction of the human body with electromagnetic fields is an active field of research. Individualized models are increasingly being used, as anatomical differences affect the simulation results. We introduce a processing pipeline for creating individual surface-based models of the human head and torso for application in simulation software based on unstructured grids.

Design and evaluation of an eye tracking support system for the scrub nurse.

Background: The availability of an increasing number of medical devices in the digital operating room has led to increased interaction demands of the surgical staff. To counteract the risk of bacterial contamination induced by device interactions, touchless interaction techniques are required. Support systems based on eye tracking enable interaction while maintaining sterility and freeing the hands to manipulate surgical instruments.

Is the built environment associated with morbidity and mortality? A systematic review of evidence from Germany.

The empirical evidence on this relationship mainly comes from Anglo-American countries whereas evidence from Germany is only emerging. Our objective is to provide a narrative overview and critical appraisal of the existing empirical evidence on the relationship between the built environment and morbidity/mortality in Germany. We conducted a systematic literature search where we included all empirical studies that linked the built environment aspects with morbidity or mortality outcomes.

In-depth statistical analysis of the use of a website providing patients' narratives on lifestyle change when living with chronic back pain or coronary heart disease.

Objective: To investigate the use of lebensstil-aendern.de ("lifestyle change"), a website providing peer narratives of experiences with successful lifestyle change, and to analyze whether peer model characteristics, clip content, and media type have an influence on the number of visitors, dwell time, and exit rates.

Methods: An in-depth statistical analysis of website use with multilevel regression analyses.

A Tuned-RF Duty-Cycled Wake-Up Receiver with -90 dBm Sensitivity.

A novel wake-up receiver for wireless sensor networks is introduced. It operates with a modified medium access protocol (MAC), allowing low-energy consumption and practical latency. The ultra-low-power wake-up receiver operates with enhanced duty-cycled listening.

Linking stem cell function and growth pattern of intestinal organoids.

Intestinal stem cells (ISCs) require well-defined signals from their environment in order to carry out their specific functions. Most of these signals are provided by neighboring cells that form a stem cell niche, whose shape and cellular composition self-organize. Major features of this self-organization can be studied in ISC-derived organoid culture.

Auditory display as feedback for a novel eye-tracking system for sterile operating room interaction.

Purpose: The growing number of technical systems in the operating room has increased attention on developing touchless interaction methods for sterile conditions. However, touchless interaction paradigms lack the tactile feedback found in common input devices such as mice and keyboards. We propose a novel touchless eye-tracking interaction system with auditory display as a feedback method for completing typical operating room tasks.

Challenges in doing multi-disciplinary health promotion research in Germany.

Health problems such as obesity are increasingly addressed by complex intervention programmes which operate at multiple levels of influence (e.g. families, schools, neighbourhoods) involving partners from various academic, professional and cultural backgrounds.