PULPO: A framework for efficient integration of life cycle inventory models into life cycle product optimization.

This work presents the PULPO (ython-based ser-defined ifecycle roduct ptimization) framework, developed to efficiently integrate life cycle inventory (LCI) models into life cycle product optimization. Life cycle optimization (LCO), which has found interest in both the process systems engineering and life cycle assessment (LCA) communities, leverages LCA data to go beyond simple assessments of a limited number of alternatives and identify the best possible product systems configuration subject to a manifold of choices, constraints, and objectives. However, typically, aggregated inventories are used to build the optimization problems.

Multiple graphical views for automatically generating SQL for the MycoDiversity DB; making fungal biodiversity studies accessible.

Fungi is a highly diverse group of eukaryotic organisms that live under an extremely wide range of environmental conditions. Nowadays, there is a fundamental focus on observing how biodiversity varies on different spatial scales, in addition to understanding the environmental factors which drive fungal biodiversity. Metabarcoding is a high-throughput DNA sequencing technology that has positively contributed to observing fungal communities in environments.

A new, unusually large, Scherer, 1974 flea beetle from Borneo, described and sequenced in the field by citizen scientists (Coleoptera, Chrysomelidae, Galerucinae).

Background: The genus Scherer 1974 consists of very small, soil-dwelling flea beetles in South, Southeast and East Asia. Due to their diminutive size and morphological similarities, very little is known about their ecology and taxonomical diversity. It is likely that further studies will reveal this genus to be much more speciose than the 30 species currently recognised.

A new semi-slug of the genus from Brunei, discovered, described and DNA-barcoded on citizen-science 'taxon expeditions' (Gastropoda, Stylommatophora, Ariophantidae).

Background: During citizen-science expeditions to the Ulu Temburong National Park, Brunei, several individuals were collected of a semi-slug species of the genus that, based on morphology and in-the-field DNA-barcoding, was found to be an undescribed species.

New Information: In this paper, we describe Wu, Ezzwan & Hamdani, n. sp.

New records of moth flies (Diptera, Psychodidae) for the Dutch Fauna.

Background: Prior to this study, the moth flies in The Netherlands were represented by 61 species. Our findings derive from a citizen-science expedition in the Vondelpark in Amsterdam, one of the oldest public parks and best known parks in The Netherlands. The combination of citizen science and the exploration of a well-known urban park has allowed us to contribute to the knowledge of moth fly species present in The Netherlands.

The network structure of posttraumatic stress symptoms in war-affected children and adolescents.

Background: It is unclear whether findings from previous network analyses of posttraumatic stress disorder (PTSD) symptoms among children and adolescents are generalizable to youth living in war-torn settings and whether there are differences in the structure and connectivity of symptoms between children and adolescents. This study examined the network structure of PTSD symptoms in a sample of war-affected youth and compared the symptom networks of children and adolescents.

Methods: The overall sample comprised 2007 youth (6-18 years old) living in Burundi, Democratic Republic of Congo, Iraq, Palestine, Tanzania, and Uganda amid or close to war and armed conflict.

An updated classification of the Brassicaceae (Cruciferae).

Based on recent achievements in phylogenetic studies of the Brassicaceae, a novel infrafamilial classification is proposed that includes major improvements at the subfamilial and supertribal levels. Herein, the family is subdivided into two subfamilies, Aethionemoideae (subfam. nov.

Lipid-mimicking phosphorus-based glycosidase inactivators as pharmacological chaperones for the treatment of Gaucher's disease.

Gaucher's disease, the most prevalent lysosomal storage disorder, is caused by missense mutation of the GBA gene, ultimately resulting in deficient GCase activity, hence the excessive build-up of cellular glucosylceramide. Among different therapeutic strategies, pharmacological chaperoning of mutant GCase represents an attractive approach that relies on small organic molecules acting as protein stabilizers. Herein, we expand upon a new class of transient GCase inactivators based on a reactive 2-deoxy-2-fluoro-β-d-glucoside tethered to an array of lipid-mimicking phosphorus-based aglycones, which not only improve the selectivity and inactivation efficiency, but also the stability of these compounds in aqueous media.

Design of a FAIR digital data health infrastructure in Africa for COVID-19 reporting and research.

The limited volume of COVID-19 data from Africa raises concerns for global genome research, which requires a diversity of genotypes for accurate disease prediction, including on the provenance of the new SARS-CoV-2 mutations. The Virus Outbreak Data Network (VODAN)-Africa studied the possibility of increasing the production of clinical data, finding concerns about data ownership, and the limited use of health data for quality treatment at point of care. To address this, VODAN Africa developed an architecture to record clinical health data and research data collected on the incidence of COVID-19, producing these as human- and machine-readable data objects in a distributed architecture of locally governed, linked, human- and machine-readable data.

First records and three new species of the family Symphytognathidae (Arachnida, Araneae) from Thailand, and the circumscription of the genus Wunderlich, 1995.

The family Symphytognathidae is reported from Thailand for the first time. Three new species: , , and are described and illustrated. Distribution is expanded and additional morphological data are reported for Lin & Li, 2009.

A review of Möllendorff, 1890 and Möllendorff, 1890 in the Philippines (Gastropoda, Pupilloidea, Hypselostomatidae).

The genera and of the Philippines are revised based on the collections of the Senckenberg Forschungsinstitut und Naturmuseum (Frankfurt am Main, Germany), the Florida Museum of Natural History (USA), and recently collected material. Three new species are described: Páll-Gergely & Auffenberg, , Páll-Gergely & Schilthuizen, , Páll-Gergely & Schilthuizen,

A new species of (Coleoptera: Chrysomelidae), discovered and described on a field course to Kuala Belalong, Brunei.

Background: is a genus of very small flea beetles living in the leaf litter layer of Asian forests, easily sampled with Winkler extraction. The genus is presumably very rich in species, but their taxonomy is hampered by their small size and morphological uniformity.

New Information: On a 'taxon expedition'-style field course at Kuala Belalong Field Studies Centre in Brunei Darussalam (Borneo), a new species, n.

A revision of (Melastomataceae, Dissochaeteae).

is a plant genus of woody climbers, classified in the tribe Dissochaeteae (Melastomataceae). The taxonomic history of the genus is complicated and includes some allied genera like , , and . Most of them are already regarded as synonyms of except for which is considered a separate genus here as well.

A review of the Cholevinae from the island of Borneo (Coleoptera, Leiodidae).

The available knowledge of the round fungus beetle subfamily Cholevinae (Leiodidae) from the island of Borneo is reviewed, and the results of newly studied material presented. The currently known 30 species (of which 14 are newly described herein) represent the genera (one species), (one species), (one species), (14 species), and (13 species). The following new species are described: Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , and Schilthuizen, Njunjić & Perreau, , and Njunjić, Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , Schilthuizen & Perreau, , and Schilthuizen & Perreau, It is expected that the cholevine biodiversity of Borneo is still far from completely known.