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63 results match your criteria: "Leibniz-Institute of Photonic Technology (Leibniz-IPHT)[Affiliation]"
J Am Chem Soc
December 2024
Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute, Beutenbergstraße 11a, 07745 Jena, Germany.
is a mold fungus that has gained attention for its positive correlation with soil health, plant growth, and applications as a crop biocontrol agent to suppress the threats of nematode pests. To date, the mechanisms underlying the protective traits of against these plant parasites have remained elusive. Here we report that abundantly produced peptidic biosurfactants, malpinin A-D, exhibit robust inhibitory activity against nematodes.
View Article and Find Full Text PDFNew Phytol
December 2024
Matthias Schleiden Institute of Genetics, Bioinformatics and Molecular Botany, Friedrich Schiller University Jena, 07743, Jena, Germany.
Photosynthetic protists, named microalgae, are key players in global primary production. The green microalga Chlamydomonas reinhardtii is a well-studied model organism. In nature, it dwells in acetate-rich paddy rice soil, which is not mimicked by standard liquid laboratory conditions.
View Article and Find Full Text PDFPLoS One
November 2024
BMD Software, Aveiro, Portugal.
Lab Chip
November 2024
Member of Leibniz Health Technologies, Member of the Leibniz Center for Photonics in Infection Research (LPI), Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Str. 9, 07745 Jena, Germany.
Here we present a highly customisable image-based fuzzy logic control (FLC) method for pressure-driven droplet microfluidics. The system is designed to position droplets of different sizes in microfluidic chips of varying channel size in the centre of the region of interest (ROI) using two parallel multiple input single output (MISO) FLCs. Overall, 95.
View Article and Find Full Text PDFDuring recent years, the optical-fiber-based simultaneous sensing of strain and temperature has attracted increased interest for different applications, e.g., in medicine, architecture, and aerospace.
View Article and Find Full Text PDFGenome Res
November 2024
Institute for Infectious Diseases and Infection Control, Jena University Hospital, 07747 Jena, Germany.
Our study investigates the effectiveness of Oxford Nanopore Technologies for accurate outbreak tracing by resequencing 33 isolates of a 3-year-long outbreak with Illumina short-read sequencing data as the point of reference. We detect considerable base errors through cgMLST and phylogenetic analysis of genomes sequenced with Oxford Nanopore Technologies, leading to the false exclusion of some outbreak-related strains from the outbreak cluster. Nearby methylation sites cause these errors and can also be found in other species besides Based on these data, we explore PCR-based sequencing and a masking strategy, which both successfully address these inaccuracies and ensure accurate outbreak tracing.
View Article and Find Full Text PDFSci Rep
September 2024
Department of Physics and Material Sciences Center, Philipps-Universität Marburg, Renthof 5, 35032, Marburg, Germany.
Smart textiles that promise to become sensors and actuators for multiple applications are an active area of research. Conductive textiles formed by coating a fabric with a conductive film will play a key role in such applications. Here we present contactless mapping of the terahertz (THz) conductivity of thin conductive films deposited on textiles.
View Article and Find Full Text PDFNanoscale Adv
September 2024
Department of Nanobiophotonics Leibniz Institute of Photonic Technology (Leibniz-IPHT), Member of the Leibniz Research Alliance - Leibniz Health Technologies Albert-Einstein-Straße 9 07745 Jena Germany
Nanomaterials made of noble metals have been actively utilized in sensorics and bioanalytics. Nanoparticles of anisotropic shapes are promising for increasing sensitivity due to the generated hotspots of electron density. Such structures can be effectively manufactured by a relatively accessible colloidal synthesis.
View Article and Find Full Text PDFSci Rep
August 2024
Department of Nanobiophotonics, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Member of the Leibniz Research Alliance - Leibniz Health Technologies, 07745, Jena, Germany.
The rapidly developing miniaturization in numerous fields require low-demanding but robust methods of nanomaterial production. Colloidal synthesis provides great flexibility in product material, size, and shape. Gold nanoparticle synthesis has been thoroughly studied, however, recent reports on mechanistic insights of crystal formation have been hindered by the numerous procedures and parameter optimization works.
View Article and Find Full Text PDFCholesterol is an important lipid playing a crucial role in mediating essential cellular processes as well as maintaining the basic structural integrity of biological membranes. Given its vast biological importance, there is an unabated need for sophisticated strategies to investigate cholesterol-mediated biological processes. Raman-tagged sterol analogs offer the advantage of being visualizable without the need for a bulky dye that potentially affects natural membrane integration and cellular interactions as it is the case for many conventionally used fluorescent analogs.
View Article and Find Full Text PDFJ Am Chem Soc
July 2024
Institute for Inorganic Chemistry 1, Ulm University (UUlm), Albert-Einstein-Allee 11, Ulm 89081, Germany.
Molecular transition metal chromophores play a central role in light harvesting and energy conversion. Recently, earth-abundant transition-metal-based chromophores have begun to challenge the dominance of platinum group metal complexes in this area. However, the development of new chromophores with optimized photophysical properties is still limited by a lack of synthetic methods, especially with respect to heteroleptic complexes with functional ligands.
View Article and Find Full Text PDFChemphyschem
September 2024
Leibniz-Institute of Photonic Technology (Leibniz-IPHT), Member of Leibniz-Health-Technologies, Member of the Leibniz-Center for Photonics in Infection Research (LPI), Jena, Germany, Albert-Einstein-Str. 9, 07745, Jena, Germany.
Raman spectroscopy was used to study the complex interactions and morphogenesis of the green seaweed Ulva (Chlorophyta) and its associated bacteria under controlled conditions in a reductionist model system. Integrating multiple imaging techniques contributes to a more comprehensive understanding of these biological processes. Therefore, Raman spectroscopy was introduced as a non-invasive, label-free tool for examining chemical information of the tripartite community Ulva mutabilis-Roseovarius sp.
View Article and Find Full Text PDFACS Omega
March 2024
Department Functional Interfaces, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Strasse 9, 07745 Jena, Germany.
Inorganic photoacids and photobases comprising of photoactive transition metal complexes (TMCs) offer the ability to modulate proton transfer reactions through light irradiation, while utilizing the excellent optical properties of the latter. This provides a powerful tool for precise control over chemical reactions and processes, with implications for both fundamental science and practical applications. In this contribution, we present a novel molecular architecture amending an Fe-NHC complex with a pendant quinoline, as a prototypical photobase, as a representative earth-abundant TMC based inorganic photobase.
View Article and Find Full Text PDFChem Commun (Camb)
February 2024
Inorganic and Analytical Chemistry (IAAC), Friedrich Schiller University Jena, Humboldtstr. 8, D-07743 Jena, Germany.
We report a specific lysosome targeted light-responsive CO-releasing molecule (Lyso-CORM). Lyso-CORM is very stable under dark conditions. CO and singlet oxygen (O) generation was effectively triggered under one photon and two photon excitation (800 nm) conditions.
View Article and Find Full Text PDFCommun Chem
August 2023
Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands.
Cardiovascular diseases are the leading cause of death worldwide and are not typically diagnosed until the disease has manifested. Endothelial dysfunction is an early, reversible precursor in the irreversible development of cardiovascular diseases and is characterized by a decrease in nitric oxide production. We believe that more reliable and reproducible methods are necessary for the detection of endothelial dysfunction.
View Article and Find Full Text PDFSci Rep
August 2023
Leibniz Institute of Photonic Technology (Leibniz IPHT), Member of Leibniz Health Technologies, Member of the Leibniz Centre for Photonics in Infection Research (LPI), PO Box 100239, 07702, Jena, Germany.
Here, we report on the development and application of a compact multi-core fiber optical probe for multimodal non-linear imaging, combining the label-free modalities of Coherent Anti-Stokes Raman Scattering, Second Harmonic Generation, and Two-Photon Excited Fluorescence. Probes of this multi-core fiber design avoid moving and voltage-carrying parts at the distal end, thus providing promising improved compatibility with clinical requirements over competing implementations. The performance characteristics of the probe are established using thin cryo-sections and artificial targets before the applicability to clinically relevant samples is evaluated using ex vivo bulk human and porcine intestine tissues.
View Article and Find Full Text PDFAnalyst
August 2023
Department of Anaesthesiology and Intensive Care Medicine and Center for Sepsis Control and Care (CSCC), Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany.
Urinary tract infections (UTI) are among the most frequent nosocomial infections. A fast identification of the pathogen and assignment of Gram type could help to prescribe most suitable treatments. Raman spectroscopy holds high potential for fast and reliable bacterial pathogens identification.
View Article and Find Full Text PDFMaterials (Basel)
July 2023
Leibniz Institute of Photonic Technology (Leibniz IPHT), Department of Functional Interfaces, Albert-Einstein-Strasse 9, 07745 Jena, Germany.
Laser safety is starting to play an increasingly important role, especially when the laser is used as a tool. Passive laser safety systems quickly reach their limits and, in some cases, provide inadequate protection. To counteract this, various active systems have been developed.
View Article and Find Full Text PDFAnalyst
July 2023
Graduate School of Chemical Sciences and Engineering, Materials Chemistry and Engineering Course, Hokkaido University, Kita 13, Nishi 8, Kita-ku, Sapporo, 060-8628, Hokkaido, Japan.
A line illumination Raman microscope extracts the underlying spatial and spectral information of a sample, typically a few hundred times faster than raster scanning. This makes it possible to measure a wide range of biological samples such as cells and tissues - that only allow modest intensity illumination to prevent potential damage - within feasible time frame. However, a non-uniform intensity distribution of laser line illumination may induce some artifacts in the data and lower the accuracy of machine learning models trained to predict sample class membership.
View Article and Find Full Text PDFMicromachines (Basel)
June 2023
Fraunhofer Institute for Applied Optics and Precision Engineering IOF, 07745 Jena, Germany.
Antireflective (AR) nanostructures offer an effective, broadband alternative to conventional AR coatings that could be used even under extreme conditions. In this publication, a possible fabrication process based on colloidal polystyrene (PS) nanosphere lithography for the fabrication of such AR structures on arbitrarily shaped fused silica substrates is presented and evaluated. Special emphasis is placed on the involved manufacturing steps in order to be able to produce tailored and effective structures.
View Article and Find Full Text PDF() colonizes up to 30% of all humans and can occasionally cause serious infections. It is not restricted to humans as it can also often be found in livestock and wildlife. Recent studies have shown that wildlife strains of usually belong to other clonal complexes than human strains and that they might differ significantly with regard to the prevalence of genes encoding antimicrobial resistance properties and virulence factors.
View Article and Find Full Text PDFJ Clin Microbiol
April 2023
Diagnostic and Research Institute of Hygiene, Microbiology and Environmental Medicine, Medical University of Graz, Graz, Austria.
Next-generation whole-genome sequencing is essential for high-resolution surveillance of bacterial pathogens, for example, during outbreak investigations or for source tracking and escape variant analysis. However, current global sequencing and bioinformatic bottlenecks and a long time to result with standard technologies demand new approaches. In this study, we investigated whether novel nanopore Q20+ long-read chemistry enables standardized and easily accessible high-resolution typing combined with core genome multilocus sequence typing (cgMLST).
View Article and Find Full Text PDFSmall
June 2023
Department of Nanobiophotonics, Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Straße 9, 07745, Jena, Germany.
Nanoparticle synthesis has drawn great attention in the last decades. The study of crystal growth mechanisms and optimization of the existing methods lead to the increasing accessibility of nanomaterials, such as gold nanotriangles which have great potential in the fields of plasmonics and catalysis. To form such structures, a careful balance of reaction parameters has to be maintained.
View Article and Find Full Text PDFChemistry
April 2023
Leibniz Institute of Photonic Technology (Leibniz-IPHT), Albert-Einstein-Street 9, 07745, Jena, Germany.
Chempluschem
March 2023
Leibniz Institute of Photonic Technology (Leibniz IPHT), Albert-Einstein-Str. 9, 07745, Jena, Germany.
In this work, we assemble amphiphilic iron(III) corroles at air-water interfaces into well-defined quasi-two-dimensional molecular monolayers and theirs stacks for sensing of nitric oxide (NO). For this purpose, we use the Langmuir-Blodgett (LB) technique, which allows varying the packing density of iron(III) corroles anchored to the aqueous subphase via one molecular side. The stacks of ten down to three molecular monolayers on the front and back sides of the substrates are sufficiently optically dense to detect NO binding to the layers photometrically.
View Article and Find Full Text PDF