3,556 results match your criteria: "Lehigh University.[Affiliation]"

Aims: Diabetes distress (DD) is prevalent among people with diabetes. While automated insulin delivery systems (AIDs) improve glycaemic control, their impact on DD is unclear. We aimed to investigate the effect of AIDs on DD in people with diabetes and their caregivers.

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Racist and xenophobic policies in the United States (e.g., family separations and lack of access to protected immigration statuses for undocumented immigrants) have historically excluded immigrants of color from accessing full civil rights, thus contributing to widening racial inequities in the US.

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Preliminary data from a prospective micro-longitudinal study (30 days) that examined the co-evolution of return to use risk among people diagnosed with an alcohol use disorder (AUD) in residential substance treatment is presented. Data assessed the feasibility of using the open dynamic interaction network (ODIN) responsive ecological momentary assessment (rEMA). rEMA collected daily estimates on affect, urges, sober-support engagement, and use.

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Accounting for learning environments in academic screening.

J Sch Psychol

February 2025

Department of Education and Human Services, Lehigh University, United States.

Within multi-tiered systems of support (MTSS) practice and research, students' need for academic intervention is often determined by comparison of students' screening scores to cut scores. We examined the degree to which the relationship between students' fall screening data (i.e.

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The thalamic reticular nucleus (TRN) is a thin shell of gap junction coupled GABAergic inhibitory neurons that regulate afferent sensory relay of the thalamus. The TRN receives dopaminergic innervation from the midbrain, and it is known to express high concentrations of D1 and D4 receptors. Although dopaminergic modulation of presynaptic inputs to TRN has been described, the direct effect of dopamine on TRN neurons and its electrical synapses is largely unknown.

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Community firearm violence (CFV), including fatal and non-fatal shootings that result from interpersonal violence, disproportionately harms people from marginalized racial groups. News reporting on CFV can further exacerbate these harms. However, examining the effects of harmful news reporting on CFV on individuals, communities, and society is hindered by the lack of a consensus definition of harmful reporting on CFV.

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The professional identity of scientists has historically been cultivated to value research over teaching, which can undermine initiatives that aim to reform science education. Course-Based Research Experiences (CRE) and the inclusive Research and Education Communities (iREC) are two successful and impactful reform efforts that integrate research and teaching. The aim of this study is to explicate the professional identity of instructors who implement a CRE within an established iREC and to explore how this identity contributes to the success of these programs.

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Article Synopsis
  • Over two decades, initiatives have aimed to enhance STEM undergraduate outcomes, with the inclusive Research Education Community (iREC) emerging as a scalable reform model that supports STEM faculty in implementing course-based research to improve student learning.
  • This study utilized pathway modeling to describe the HHMI Science Education Alliance (SEA) iREC, identifying how faculty engagement leads to sustainable adoption and improvement of new teaching strategies through feedback from over 100 participating faculty members.
  • The findings indicate that iREC fosters a collaborative environment where STEM faculty can share expertise and data, thereby enhancing their teaching practices and contributing to the overall evolution of undergraduate science education.
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Microdroplet Resuspension Off Surfaces.

Langmuir

December 2024

Department of Chemical and Biomolecular Engineering, Lehigh University, 19 Memorial Drive West, Bethlehem, Pennsylvania 18015, United States.

Understanding the resuspension of droplets from surfaces into air is important for elucidating a range of processes such as disease transmission of airborne pathogens and determining environmental contamination and the effectiveness of cleaning procedures. The resuspension condition is defined as the escape velocity of a droplet from a surface. This study investigated the dynamics of microliter-sized droplet resuspension off surfaces utilizing a novel free-fall device.

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People generate evaluations of different attitude objects based on their goals and aspects of the social context. Prior research suggests that people can shift between at least three types of evaluations to judge whether something is good or bad: (how costly or beneficial it is), (whether it is aligned with moral norms), and (whether it feels good; Van Bavel et al., 2012).

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Evolving Emulsion Microcompartments via Enzyme-Mimicking Amyloid-Mediated Interfacial Catalysis.

Small

December 2024

State Key Laboratory of Chemical Resource Engineering, Key Lab of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology, Ministry of Education), Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.

Living organisms take in matter and energy from their surroundings, transforming these inputs into forms that cells can use to sustain metabolism and power various functions. A significant advancement in the development of protocells and life-like materials has been the creation of cell-like microcompartments capable of evolving into higher-order structures characterized by hierarchy and complexity. In this study, a smart emulsion system is designed to digests chemical substrates and generates organic or inorganic products, driving the self-organization and structuration of microcompartments.

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Expanding the Reaction Network of Ethylene Epoxidation on Partially Oxidized Silver Catalysts.

ACS Catal

December 2024

Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, Pennsylvania 18015, United States.

An extended microkinetic model (MKM) for the selective oxidation of ethylene to ethylene oxide (EO) is presented, based on an oxidic representation of the silver (Ag) surface, namely, the p(4 × 4) oxidic reconstruction of the Ag(111) phase to mimic the significant oxygen coverage under reaction conditions, as is evidenced by recent operando spectroscopic studies. The MKM features three pathways each for producing either ethylene oxide (EO) or carbon dioxide (CO), including the common intermediate or oxometallacycle (OMC) pathway, an atomic oxygen pathway, as well as pathways centered around the role of a diatomic oxygen species occupying an oxygen vacancy (O/O*). The MKM uses a composite set of experimental and density functional theory (DFT) kinetic parameters, which is further optimized and trained on experimental reaction data.

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This secondary analysis re-examined stories of caregiving told by NICU nurses in the southeast US through a trauma theory lens expanding on research surrounding substance-exposed pregnancies. Narrative analysis identified distress-related experiences of nurses related to child custody decisions and outcomes, suggesting traumatic stress within this caregiving dynamic. Four distinct story types and three themes were identified across 23 stories, highlighting similarities and differences and illustrating how distress and trauma were experienced and may be manifested in care practices.

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A variety of early literacy assessments are available to monitor student response to instruction in early reading skills. The purpose of this study was to explore the degree to which growth during the second half of kindergarten on measures of alphabetic principle (i.e.

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Coacervation for biomedical applications: innovations involving nucleic acids.

Soft Matter

December 2024

Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA 18015, USA.

Gene therapies, drug delivery systems, vaccines, and many other therapeutics, although seeing breakthroughs over the past few decades, still suffer from poor stability, biocompatibility, and targeting. Coacervation, a liquid-liquid phase separation phenomenon, is a pivotal technique increasingly employed to enhance the effectiveness of therapeutics. Through coacervation strategies, many current challenges in therapeutic formulations can be addressed due to the tunable nature of this technique.

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TGNet: tensor-based graph convolutional networks for multimodal brain network analysis.

BioData Min

December 2024

Department of Computer Science and Engineering, Lehigh University, 113 Research Drive, Bethlehem, 18015, PA, USA.

Article Synopsis
  • The paper discusses a new approach called TGNet, a tensor-based graph convolutional network, designed to analyze multimodal brain networks more effectively than current methods.
  • TGNet combines tensor decomposition with multi-layer graph convolutional networks to capture both simple and complex brain network structures.
  • The framework has been tested on data from various neurological disorders and shows improved accuracy in disease classification, especially when sample sizes are small, showcasing its potential for future research.
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Article Synopsis
  • The study investigated how insomnia relates to anxiety and depression over three years among 3,415 older adults aged 66-103.
  • It found that both onset and maintenance of insomnia play a role in the relationship between anxiety and depressive symptoms, acting as mediators.
  • The researchers suggest further studies are needed to explore these findings, which could help in developing prevention and treatment strategies for insomnia and mental health issues in older adults.
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Polythiophene side chain chemistry and its impact on advanced composite anodes for lithium-ion batteries.

Chem Commun (Camb)

December 2024

Department of Chemical and Bimolecular Engineering, Lehigh University, Bethlehem, PA, 18015, USA.

In the development of high-performance lithium-ion batteries (LIBs), the design of polymer binders, particularly through manipulation of side-chain chemistry, plays a pivotal role in optimizing electrode stability, ion transport, and adaptability to the volume changes during cycling. In particular, poly[3-(potassium-4-butanoate)thiophene-2,5-diyl] (P3KBT) increases magnetite and silicon capacity and cycling stability. This work explores the impact of polythiophene alkyl sidechain length on anode characteristics, aiming to enhance performance in LIBs.

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Controlling Ion Uptake in Carboxylated Mixed Conductors.

Adv Mater

December 2024

Department of Chemical and Biomolecular Engineering, Lehigh University, Bethlehem, PA, 18015, USA.

Organic mixed ionic-electronic conductors (OMIECs) have garnered significant attention due to their capacity to transport both ions and electrons, making them ideal for applications in energy storage, neuromorphics, and bioelectronics. However, charge compensation mechanisms during the polymer redox process remain poorly understood, and are often oversimplified as single-ion injection with little attention to counterion effects. To advance understanding and design strategies toward next-generation OMIEC systems, a series of p-channel carboxylated mixed conductors is investigated.

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The distributions of anthozoan corals are undercharacterized due to their wide bathymetric ranges, occurrences in remote locales, and difficulties of identification from morphology alone. Environmental DNA (eDNA) sequencing promises to be a noninvasive strategy to complement conventional approaches for mapping and monitoring the distribution and biodiversity of coral communities. Primers for eDNA metabarcoding have been designed to amplify nuclear and mitochondrial DNA barcodes in shallow scleractinians and mitochondrial in deep-sea octocorals.

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Volcanic activity has been shown to affect Earth's climate in a myriad of ways. One such example is that eruptions proximate to surface ice will promote ice melting. In turn, the crustal unloading associated with melting an ice sheet affects the internal dynamics of the underlying magma plumbing system.

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Project G-SPACE: protocol for exploring the influence of green space on sleep and mental health among children.

BMC Pediatr

November 2024

Department of Behavioral and Social Sciences, Department of Epidemiology, Center for Health Promotion and Health Equity, School of Public Health, Brown University, Providence, RI, USA.

Background: The prevention of pediatric mental health disorders is a growing health priority in the United States. While exposure to green space, such as outdoor vegetation, has been linked with improved mental health outcomes in children, little is known about the impact of green space on children's sleep. Sleep has many benefits, but the factors affecting both sleep and mental health as they relate to green space exposure are not well understood in children.

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Tailored Ni(OH)/CuCo/Ni(OH) Composite Interfaces for Efficient and Durable Urea Oxidation Reaction.

ACS Appl Mater Interfaces

December 2024

Department of Chemical and Biomolecular Engineering, Lehigh University, 111 Research Dr., Bethlehem, Pennsylvania 18015, United States.

Electrocatalytic urea oxidation reaction is a promising alternative to water oxidation for more efficient hydrogen production due to its significantly lower thermodynamic potential. However, achieving efficient electrochemical urea oxidation remains a formidable challenge, and development of an improved electrocatalyst with an optimal physicochemical and electronic structure toward urea oxidation is desired. This can be accomplished by designing a tailored two-dimensional composite with an abundance of active sites in a favorable electronic environment.

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Considering the role of human interactions in infectious disease outbreaks and cooperation in mitigating natural disasters consequences, ecological threats to human survival have been among proposed drivers of collectivism. Utilizing established and novel measures of parasite stress and natural disasters, we investigated their association with collectivism in a large sample of countries (N = 188). Linear mixed-effect models indicated that after controlling for national wealth, neither natural disasters nor infectious disease can predict collectivism scores.

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Anti-PD-L1 Antibody Fragment Linked to Tumor-Targeting Lipid Nanoparticle Can Eliminate Cancer and Its Metastasis via Photoimmunotherapy.

ACS Nano

December 2024

Department of Microbiology, Brain Korea 21 Project, University of Ulsan College of Medicine, ASAN Medical Center, Seoul 05505, South Korea.

Effective cancer therapy aims to treat primary tumors and metastatic and recurrent cancer. Immune checkpoint blockade-mediated immunotherapy has shown promising effects against tumors; however, its efficacy in metastatic or recurrent cancer is limited. Here, based on the advantages of nanomedicine, lipid nanoparticles (LNPs) that can target tumors are synthesized for photothermal therapy (PTT) and immunotherapy to treat primary and metastatic recurrent cancer.

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