Impact of Persistent Combat-Related PTSD on Heart Disease and Chronic Disease Comorbidity in Aging Vietnam Veterans.

Objectives: To assess combat and combat-related posttraumatic stress disorder (PTSD) as risk factors for heart disease and non-cardiac chronic disease comorbidity in deployed Vietnam veterans 50 years post-War.

Methods: A random sample of 735 Vietnam-deployed American Legionnaires was surveyed in 1984, 1998, and 2000 for combat exposure, probable PTSD, and history of diagnosed chronic illnesses.

Results: Twenty-eight percent reported a diagnosed heart condition; combat exposure in Vietnam was a significant predictor (OR = 1.

Incorporating incubation period distributions to precisely estimate the association between rainfall and Legionella infection.

Background: Multiple studies have shown a positive relationship between weather events and, 1 to 2 weeks later, Legionnaires' disease (LD) cases. Narrowing this time window of association can help determine whether the mechanism linking rainfall and relative humidity to sporadic LD is direct or indirect. Due to the large number of daily water interactions and low incidence of LD, we propose a new Bayesian modeling approach to disentangle the potential for a direct vs.

Demonstration of cavitary legionnaires' pneumonia in a renal transplant recipient.

Legionella pneumophila is a potentially life-threatening infection, especially for individuals with compromised cell-mediated immunity. Typical chest CT findings include multilobed or multisegmented consolidations and ground-glass opacities, but cavitary lesions are rare. This case report details a 29-year-old male renal transplant recipient who developed cavitary Legionnaires' pneumonia.

Two Sporadic Cases of Legionellosis Associated with the Use of Domestic Ultrasonic Humidifiers.

Two sporadic cases of legionellosis occurring in consecutive years were confirmed by positive antigenuria to serogroup 1 in individuals with limited mobility who were confined to their homes. Both cases had a history of using ultrasonic humidifiers and of low exposure to other possible sources of infection. This study was conducted through an expanded epidemiological survey and home inspection.

Distinction of clinical features and microbiological methods between and pneumonia confirmed by metagenomic next-generation sequencing.

Objectives: Detection and diagnosis of () pneumonia is often overlooked due to conventional methods limitations and similarity to other atypical community acquired pneumonia (CAP). Using mNGS, we aimed to distinguish psittacosis from legionellosis for early pneumonia diagnosis and better prognosis.

Methods: Thirty-seven patients diagnosed with atypical CAP were enrolled in this retrospective study, including 14  pneumonia and 23 () pneumonia.

A comprehensive two-hybrid analysis to explore the effector-effector interactome.

Unlabelled: uses over 300 translocated effector proteins to rewire host cells during infection and create a replicative niche for intracellular growth. To date, several studies have identified effectors that indirectly and directly regulate the activity of other effectors, providing an additional layer of regulatory complexity. Among these are "metaeffectors," a special class of effectors that regulate the activity of other effectors once inside the host.

Case report: First report of and coinfection in an immunocompromised patient.

Legionnaires' disease (LD) is a serious type of pneumonia, typically contracted by susceptible people through the inhalation of aerosols contaminated with . In this report, the first case of coinfection with - is described. A possible source of the Lp infection may be the hotel in Paris (France) where the patient had stayed before developing the symptoms.

[A paramedical team "on the front line" of hospital care for legionnaires].

The psychiatric department at the Laveran Army Training Hospital in Marseille is a referral center for legionnaires, a population at high risk of psychological trauma. As part of a multi-disciplinary team, nurses and orderlies play a major role in their care. The dual status of caregiver and soldier is an asset in providing comprehensive care for psychologically injured legionnaires.

Expanded geographic distribution for two sequence types of clinical concern.

serogroup 1 sequence types (ST) 213 and 222, a single-locus variant of ST213, were first detected in the early 1990s in the Midwest United States (U.S.) and the late 1990s in the Northeast U.

Two Outbreaks of Legionnaires Disease Associated with Outdoor Hot Tubs for Private Use - Two Cruise Ships, November 2022-July 2024.

Legionnaires disease is a serious pneumonia caused by Legionella bacteria. During November 2022-June 2024, CDC was notified of 12 cases of Legionnaires disease among travelers on two cruise ships; eight on cruise ship A and four on cruise ship B. CDC, in collaboration with the cruise lines, initiated investigations to ascertain the potential sources of on-board exposure after notification of the second potentially associated case for each ship.