163 results match your criteria: "Legacy Emanuel Medical Center[Affiliation]"

Real-time attending trauma surgeon assessment of direct-to-operating room trauma resuscitations: Results from a prospective observational study.

J Trauma Acute Care Surg

September 2024

From the Division of Trauma and Acute Care Surgery, Department of Surgery (H.L., J.D., M.M.), Los Angeles General Medical Center, Los Angeles, California; and Trauma and Acute Care Surgery Service, Department of Surgery (A.J., A.K., M.R., F.C., R.B., W.L.), Legacy Emanuel Medical Center, Portland, Oregon.

Background: Direct-to-operating room (DOR) resuscitation expedites interventions for trauma patients. Perceived benefit from the surgeon's perspective is not well known. This study assesses the integration of a real-time surgeon assessment tool into a DOR protocol.

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Article Synopsis
  • * Conducted in multiple hospitals from 2018-2020, the study involved pediatric patients aged 18 months to 17 years and utilized a handheld ultrasound device to collect data for training the algorithm.
  • * Results showed the algorithm achieved an accuracy of 88.5% in identifying lung consolidation, with strong sensitivity and specificity, suggesting it could be effective in clinical settings for diagnosing pneumonia.
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A letter response to indications for oxygen therapy and the Undersea and Hyperbaric Medical Society.

Med Gas Res

December 2024

Program Medical Director for Hyperbaric Medicine and Chronic Wound Care, Legacy Emanuel Medical Center, Portland, OR, USA; Hyperbaric Oxygen Therapy Committee, Undersea & Hyperbaric Medical Society, North Palm Beach, FL, USA.

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Fibula Reconstruction of the Maxilla and Midface.

Atlas Oral Maxillofac Surg Clin North Am

September 2024

Head and Neck Surgical Associates, 1849 Northwest Kearney Street, Suite 300, Portland, OR 97209, USA; Legacy Good Samaritan Cancer Center and Legacy Emanuel Medical Center, Portland, OR, USA; Providence Cancer Center, Portland, OR, USA.

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Stroke in critically ill patients with respiratory failure due to COVID-19: Disparities between low-middle and high-income countries.

Heart Lung

October 2024

Division of Neuroscience Critical Care, Departments of Neurology, Neurosurgery, and Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Article Synopsis
  • A study was conducted to compare stroke incidences and mortality rates in critically ill COVID-19 patients from low-and middle-income countries (LMICs) and high-income countries (HICs).
  • The results showed that stroke incidence was significantly higher in LMICs (35.7 per 1000 admitted-days) compared to HICs (17.6 per 1000 admitted-days), with patients from LMICs also facing higher mortality rates (43.6% vs. 29.2%).
  • The findings highlight the need for better stroke diagnosis and healthcare resource allocation in LMICs, as both higher income status and the presence of stroke are associated with increased risk of death
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Article Synopsis
  • * An 18-year-old female ingested a dangerous amount of bupropion, resulting in severe health issues including status epilepticus and heart complications, requiring advanced life support measures like ECMO.
  • * After receiving intensive care, including aggressive treatments for her heart issues, the patient made a full recovery and was discharged neurologically intact, highlighting the importance of quick action in bupropion overdose cases.
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There is little research informing appropriate specialty palliative care consultation over primary palliative care practice, or the ability of the burn surgeon to perform skills such as effective goals of care discussions. We sought to characterize patterns of palliative care utilization and hypothesized that greater modified Baux (mBaux) and systemic organ failure assessment (SOFA) scores would correlate with increased specialty palliative involvement but have no relationship with primary palliative involvement. A retrospective chart review was conducted at a regional burn center between 2020-2021 including patients admitted with burns or inhalation injury and a mBaux score over 60, detailing circumstances of palliative consultation and goals of care discussions.

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Article Synopsis
  • - The study explores pre-mRNA splicing, its critical role in neurodevelopment, and how mutations in spliceosome-related genes U2AF2 and PRPF19 contribute to neurodevelopmental disorders (NDDs).
  • - Researchers found multiple pathogenic variants in U2AF2 and PRPF19 across unrelated individuals, with functional analysis showing that specific U2AF2 variants disrupted normal splicing and neuritogenesis in human neurons.
  • - Additionally, investigations in Drosophila models revealed that the loss of function in U2AF2 and PRPF19 caused severe developmental defects and social issues, pointing to a genetic network wherein splicing factors like Rbfox1 play a significant role in brain development and function. *
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Article Synopsis
  • * A three-phase methodology was used to develop a core outcome domain set for clinical trials targeting NF1-associated cNF, involving a systematic literature review, international consensus process, and voting.
  • * The final outcome domains included 'clinical assessment,' 'daily life impact,' 'patient satisfaction,' and 'perception of health,' with consensus reached among stakeholders on how to best evaluate treatment effectiveness for this condition.
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Emergency department thoracotomy in children: A Pediatric Trauma Society, Western Trauma Association, and Eastern Association for the Surgery of Trauma systematic review and practice management guideline.

J Trauma Acute Care Surg

September 2023

From the Division of General Surgery (L.S., L.-Y.W., S.D.), Oregon Health & Sciences University, Portland, Oregon; Department of Surgery (B.Y., M.C.), University of Florida College of Medicine-Jacksonville, Florida; Department of Surgery (M.M.), Los Angeles County + University of Southern California Medical Center, Los Angeles, California; Department of Surgery (G.N.), Texas Tech University Health Sciences Center El Paso, El Paso, Texas; Division of Acute Care Surgery (K.M.), Loma Linda University Medical Center, Loma Linda, California; Department of Surgery (R.I.), University of California San Diego School of Medicine/Rady Childrens Hospital San Diego, San Diego, California; Department of Surgery (J.F.), Burnett School of Medicine at Fort Worth, Texas; Department of Surgery (S.W.L.), East Carolina University, Greenville, North Carolina; Department of Surgery (C.G.), University of Texas Health San Antonio, San Antonio, Texas; Department of Pediatric Surgery (K.T.F.-B.), Medical College of Wisconsin, Children's Wisconsin, Milwaukee, Wisconsin; and Division of Pediatric Surgery (M.J.), Doernbecher Children's Hospital, Oregon Health & Sciences University; and Randall Children's Hospital (M.J.), Legacy Emanuel Medical Center, Portland, Oregon.

Background: The role of emergency department resuscitative thoracotomy (EDT) in traumatically injured children has not been elucidated. We aimed to perform a systematic review and create evidence-based guidelines to answer the following PICO (population, intervention, comparator, and outcome) question: should pediatric patients who present to the emergency department pulseless (with or without signs of life [SOL]) after traumatic injuries (penetrating thoracic, penetrating abdominopelvic, or blunt) undergo EDT (vs. no EDT) to improve survival and neurologically intact survival?

Methods: Using Grading of Recommendations Assessment, Development and Evaluation methodology, a group of 12 pediatric trauma experts from the Pediatric Trauma Society, Western Trauma Association, and Eastern Association for the Surgery of Trauma assembled to perform a systematic review.

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Reconstructing the Mandible: Jaw-In-A-Day: Where We Were, Where We Are, and the Future.

Atlas Oral Maxillofac Surg Clin North Am

September 2023

Division of Oral and Maxillofacial Surgery, Department of Dental Medicine, Northwell Health, Long Island Jewish Medical Center, 270-05 76th Avenue, New Hyde Park, NY 11040, USA.

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Background: SARS-CoV-2 positive status has been considered a predominantly incidental finding among trauma patients. We sought to examine whether concurrent infection is associated with worse outcomes in a contemporary cohort of injured patients during the COVID-19 pandemic.

Methods: Retrospective cohort analysis of a level I trauma center's institutional registry from May 1, 2020 through June 30, 2021.

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TQIP mortality reporting system case reports: Unanticipated mortality due to airway loss.

J Trauma Acute Care Surg

May 2023

From the Division of Acute Care Surgery, Department of Surgery (J.W.S.), University of Michigan, Ann Arbor, Michigan; Division of Trauma, Legacy Emanuel Medical Center (F.J.C.), Portland, California.

The Trauma Quality Improvement Program Mortality Reporting System is an online anonymous case reporting system designed to share experiences from rare events that may have contributed to unanticipated mortality at contributing trauma centers. The Trauma Quality Improvement Program Mortality Reporting System Working Group monitors submitted cases and organizes them into emblematic themes. This report summarizes unanticipated mortality from 3 cases of airway loss in injured patients and presents strategies to mitigate these events locally, with the hope of decreasing unanticipated mortality nationwide.

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Opioid and non-opioid analgesic prescribing practices for pediatric adenotonsillectomy in a tertiary care center.

Int J Pediatr Otorhinolaryngol

December 2022

Duke University School of Medicine, Department of Head and Neck Surgery & Communication Sciences, Durham, NC, 27710, USA. Electronic address:

Importance: The U.S. is in an opioid epidemic with greater than 40,000 deaths annually.

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Background: The purpose of this study was to analyze injury characteristics and stroke rates between blunt cerebrovascular injury (BCVI) with delayed vs non-delayed medical therapy. We hypothesized there would be increased stroke formation with delayed medical therapy.

Methods: This is a sub-analysis of a 16 center, prospective, observational trial on BCVI.

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Surgical scalpel handles and blades.

Br J Surg

September 2022

Department of Trauma and General Surgery, Legacy Emanuel Medical Center, Portland, Oregon, USA.

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Utilizing a Nasal Speculum in Maxillofacial Trauma and Deep Space Neck Infections: A Technical Note.

J Oral Maxillofac Surg

September 2022

Fellowship Director, Head and Neck Oncologic and Microvascular Surgery, Providence Cancer Institute, Medical Director, Craniomaxillofacial and Neck Trauma, Legacy Emanuel Medical Center, Head and Neck Surgical Associates, Portland, Oregon. Electronic address:

Maxillofacial trauma and odontogenic infections demand surgical access to sites often distant from wounds or incisions. We describe a simple, cost-effective, safe, and easy-to-implement technique of using a nasal speculum to facilitate surgical access in deep wounds of the head and neck region. This manuscript will describe 2 common indications and the technique for employing the nasal speculum as an adjunctive tool in oral and maxillofacial surgery.

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Pregnancy in trauma-A Western Trauma Association algorithm.

J Trauma Acute Care Surg

October 2022

From the Robert Packer Hospital, The Guthrie Clinic (A.R.), Legacy Emanuel Medical Center, Portland, OR (M.M.), University of Southern California, CA (K.I.), Oregon Health and Science University, Portland, OR (M.S., K.B.), Medstar Georgetown, Washington, DC (J.S.), University of South Florida, Miami, Florida (D.C.), University of Pittsburgh, Pittsburgh, PA (J.S.), University of Maryland, Baltimore (R.K.), University of Texas, Austin, TX (C.B.), and Denver Health, Denver, Colorado (E.M.).

Background: The Western Trauma Association has undertaken publication of best practice clinical practice guidelines on multiple trauma topics. These guidelines are based on scientific evidence, case reports, and best practices per expert opinion. Some of the topics covered by this consensus group do not have the ability to have randomized controlled studies completed because of complexity, ethical issues, financial considerations or scarcity of experience.

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Adenosine-A Receptor Signaling Plays a Crucial Role in Sudden Unexpected Death in Epilepsy.

Front Pharmacol

June 2022

Department of Pediatric Neurology, Randall Children's Hospital, Legacy Emanuel Medical Center, Portland, OR, United States.

Adenosinergic activities are suggested to participate in SUDEP pathophysiology; this study aimed to evaluate the adenosine hypothesis of SUDEP and specifically the role of adenosine A receptor (AR) in the development of a SUDEP mouse model with relevant clinical features. Using a combined paradigm of intrahippocampal and intraperitoneal administration of kainic acid (KA), we developed a boosted-KA model of SUDEP in genetically modified adenosine kinase (ADK) knockdown (Adk) mice, which has reduced ADK in the brain. Seizure activity was monitored using video-EEG methods, and recording of local field potential (LFP) was used to evaluate neuronal activity within the nucleus tractus solitarius (NTS).

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The use of extracorporeal membrane oxygenation (ECMO) is growing rapidly in all patient populations, especially adults for both acute lung or heart failure. ECMO is a complex, high risk, resource-intense, expensive modality that requires appropriate planning, training, and management for successful outcomes. This article provides an optimal approach and the basic framework for initiating a new ECMO program, which can be tailored to meet local needs.

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Glucagon-like peptide-1 receptor agonists (GLP-1 agonists) are effective hemoglobin A1c (HbA1c) and weight-lowering agents. The treatment effect is unknown in patients with HbA1c of 9% or greater. The purpose of this study was to evaluate glycemic control and weight loss after adding a GLP-1 agonist in patients with a baseline HbA1c of 9% (75 mmol/mol) or greater.

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Introduction: Many postoperative acute care visits (PACVs) are likely more appropriately addressed in lower acuity settings; however, the frequency and nature of PACVs are not currently tracked by the National Surgical Quality Improvement Program (NSQIP), and the overall burden to emergency departments and urgent care centers is unknown.

Methods: NSQIP collaborative data were augmented to prospectively capture 30-d PACVs for 1 y starting October 2018 across all NSQIP specialties, including visit reason and disposition. Data were analyzed using binomial logistic regression.

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Introduction: The use of glucocorticoid as local anesthetic adjuvant in single-injection adductor canal block (ACB) is well-documented but its effects in the presence of an indwelling catheter is unclear. The purpose of this study was to determine the impacts of one-time perineural glucocorticoid injection on continuous adductor canal block in patients undergoing total knee arthroplasty.

Methods: A single center retrospective study of 95 patients undergoing unilateral total knee arthroplasty (TKA) was performed.

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Shiga toxin-producing hemolytic uremic syndrome (STEC-HUS) is the most common cause of acute renal failure in children, and it is associated with thrombocytopenia and hemolytic anemia. Although this disease primarily affects the kidney, it can also contribute to cellular damage in other organ systems, such as the CNS. Eculizumab is a monoclonal antibody that binds to complement proteins to prevent complement-mediated intravascular hemolysis in atypical HUS.

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