410 results match your criteria: "Lebanese American University Medical Center.[Affiliation]"

Background: Metabolic dysfunction associated fatty liver disease (MAFLD) is a highly prevalent non-communicable disease whose prevalence is reaching pandemic proportions. Its implications constitute a major public health concern. To date, no validated tool measures knowledge and attitudes towards MAFLD in young adults in the Middle East and North Africa region.

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Left atrial strain (LAS) was recently introduced as a parameter that reflects on left atrial function. Consequently, changes in LAS can inform the development of cardiovascular diseases, hence providing a window for non-invasive and cost-effective testing of these diseases and their complications at early stages of development, potentially offering a segway towards preventive interventions. LAS has yet to be implemented into standard practice.

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Preoperative hemoglobin level and anemia frequency among patients admitted for diabetic lower extremity amputation.

Vascular

December 2024

Department of Orthopedic Surgery, Lebanese American University Medical Center-Rizk Hospital, Lebanese American University, School of Medicine, Beirut, Lebanon.

Objectives: Anemia is known to be prevalent in patients with diabetic foot ulcers, but such was not documented in those who required lower extremity amputations (LEAs). In this high-risk population, preoperative anemia could be an additional risk factor for postoperative morbidity and mortality. This study attempts to address the knowledge gap related to the preoperative hemoglobin (Hg) level and anemia prevalence in patients admitted for diabetic LEA.

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Geroderma Osteodysplastica (GO) is a rare autosomal recessive connective tissue disease characterized by wrinkled skin and osteoporosis, two distinct aging-related features. A loss of function mutation in results in the disease. Immediately after birth, a cyanotic female neonate was found to have transposition of great vessels (TGV) that was corrected with an uneventful surgical recovery.

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Co-occurrence of Loeys-Dietz syndrome with postural orthostatic tachycardia syndrome: A case series.

Auton Neurosci

December 2024

Neurological Institute, University Hospitals Cleveland Medical Center, Cleveland, OH, United States of America; Department of Neurology, Case Western Reserve University School of Medicine, Cleveland, OH, United States of America.

Loeys-Dietz syndrome (LDS) is a connective tissue disorder arising from mutations in the TGF- β signaling pathway. The spectrum of clinical manifestations is broad, and includes vascular, skeletal, and craniofacial abnormalities, along with joint hypermobility. No evidence of postural orthostatic tachycardia syndrome (POTS) in these patients has been reported.

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Lebanon has faced a series of crises, starting with the economic collapse in 2019, followed by the COVID-19 pandemic, and the Beirut blast on August 4, 2020. These events have left the population vulnerable to psychological distress. Our study aims to assess the psychological impact of the Beirut explosion on Lebanese healthcare providers.

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Keller and Interphalangeal Joint Resection Arthroplasties for Chronic Noncomplicated Diabetic Ulcers of the Hallux: A Systematic Review and Meta-analysis.

Foot Ankle Orthop

October 2024

Department of Orthpedic Surgery, Lebanese American University Medical Center-Rizk Hospital, Lebanese American University, School of Medicine, Lebanon.

Background: Surgery is often needed for resistant plantar diabetic foot ulcers (DFUs) of the big toe. For noninfected ulcers, 2 types of surgery are available: the Keller and the hallux interphalangeal joint arthroplasty (HIPJ-A) procedures. Yet, no evidence synthesis on the outcomes of these procedures has been conducted; thus, this systematic review is an attempt to fill this gap.

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Lyell syndrome, also known as toxic epidermal necrolysis (TEN), is a rare but life-threatening skin condition, often triggered by certain medications. Antiepileptics, allopurinol, and some nonsteroidal anti-inflammatory drugs are the most common causes. Some antibiotics are also common culprits, although tetracyclines are rarely linked to this condition.

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Varicella-zoster virus (VZV) can lead to rare complications such as cutaneous vasculitis. We present a unique case of post-zoster cutaneous vasculitis in an 82-year-old male, occurring alongside acute calcium pyrophosphate deposition disease (CPPD), a previously undocumented association. The patient initially presented with a painful zoster rash and hand swelling, treated with oral acyclovir.

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Article Synopsis
  • A study was conducted to evaluate the effects of a training program for oocyte retrieval (ORSTP) on the clinical performance of medical residents.
  • Residents who completed the ORSTP showed similar rates of successful oocyte retrieval compared to those who did not receive the training.
  • Although the training did not enhance the actual performance metrics, it was found that those who underwent the training experienced less stress and had greater confidence in their oocyte retrieval abilities.
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Introduction: Rare coagulation disorders (RCDs) constitute an important health risk. Data on epidemiology, quality of life (QoL), access to care, and impact of the ongoing economic crisis on RCDs in Lebanon is limited.

Aim: We aimed to address these gaps by evaluating effect of the crisis on the management of RCDs.

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Locally advanced/metastatic non-small-cell lung cancer in Lebanon: focus on ALK tyrosine kinase inhibitors.

Future Oncol

November 2024

Department of Hematology-Oncology, Hôtel-Dieu de France University Hospital, Faculty of Medicine, Saint-Joseph University of Beirut, Beirut, 166830, Lebanon.

Treatment of non-small-cell lung cancers (NSCLC) has evolved over the last decade. According to studies, the use of targeted therapies has significantly increased the life expectancy of patients. Moreover, ALK-tyrosine kinase inhibitors (ALK-TKIs) have improved clinical outcomes.

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Introduction: Fractures involving the ankle joint typically manifest as bimalleolar or trimalleolar fractures, with isolated posterior malleolus fractures (IPMF) representing a rare subset, comprising 0.5-4 % of cases. Due to its rarity and subtle clinical presentation, IPMF poses unique diagnostic and management challenges.

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Article Synopsis
  • Wolf-Hirschhorn syndrome (WHS) is a rare genetic disorder linked to a microdeletion on chromosome 4p, leading to unique facial characteristics, growth delays, various levels of intellectual disabilities, epilepsy, and heart issues.
  • Anesthetic management for children with WHS is complex and needs to be customized due to the syndrome's multisystem effects, and there's no definitive best practice yet.
  • An eight-year-old WHS patient undergoing strabismus surgery was successfully managed using a supraglottic device, overcoming concerns of difficult intubation and minimizing aspiration risks.
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Surgical face masks (SFM) are pivotal in preventing surgical site infections (SSI) in the operating room (OR). However, there are currently no specific recommendations for their most effective use. SFM effectiveness is influenced by factors such as material, fit, and duration of use, sparking ongoing debates about their benefits and risks in surgery.

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Article Synopsis
  • A meta-analysis compared arthroscopic and open surgical methods for lateral epicondylitis, focusing on functional recovery, pain, complications, and return-to-work time, using data from 19 studies with over 20,000 participants.
  • Results showed no significant differences in post-surgery recovery scores or complication rates between the two techniques, highlighting their comparable efficacy.
  • However, arthroscopic surgery resulted in a shorter return-to-work time and a temporary improvement in grip strength six months post-operation.
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Effect of adequacy of empirical antibiotic therapy for hospital-acquired bloodstream infections on intensive care unit patient prognosis: a causal inference approach using data from the Eurobact2 study.

Clin Microbiol Infect

December 2024

OUTCOMEREA Research Group, Drancy, France; Institut National de la Santé et de la Recherche Medicale, Infection Antimicrobial Modelisation Evolution, U1137, Team Decision Science in Infectious Diseases, Paris, France; Assistance Publique Hôpitaux de Paris, Bichat hospital, Medical and infectious diseases ICU, F75018, Paris France. Electronic address:

Article Synopsis
  • Hospital-acquired bloodstream infections (HA-BSI) in ICU patients can be life-threatening, and this study aimed to see how early adequate antibiotic treatment affects 28-day mortality rates for patients who survive at least one day after infection onset.
  • Using data from a multicenter study with 2,418 patients, researchers found that those who received adequate treatment within 24 hours had a lower 28-day mortality rate (32.8%) compared to those who were inadequately treated (40%).
  • The study concluded that inadequate antibiotic therapy within 24 hours contributes significantly to 28-day mortality, indicating that quicker treatment could greatly improve patient outcomes in cases of HA-BSI.
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A healthy 14-year-old boy presented with a 2-month history of two slowly expanding asymptomatic lesions on his right trunk. No etymology of any new medications, recent travel, or tick bites was reported. Physical examination demonstrated two 4.

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In this study, we conducted a case-control investigation to assess the immunogenicity and effectiveness of primary and first booster homologous and heterologous COVID-19 vaccination regimens against infection and hospitalization, targeting variants circulating in Lebanon during 2021-2022. The study population comprised active Lebanese military personnel between February 2021 and September 2022. Vaccine effectiveness (VE) against laboratory-confirmed SARS-CoV-2 infection and associated hospitalization was retrospectively determined during different variant-predominant periods using a case-control study design.

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Article Synopsis
  • Point-of-care ultrasound (POCUS) is becoming essential in emergency medicine, providing quick imaging at the bedside.
  • A study in Lebanon found that a significant number of medical residents (58.3%) only have basic POCUS knowledge, while 19.6% lack any knowledge and only 21.6% are adequately proficient.
  • To improve POCUS education, residency programs should implement standardized training, simulation exercises, and enhance faculty development to equip residents with the skills needed for effective clinical use.
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Conservative surgery in the management of diabetic foot complications (excluding Charcot). The role of the orthopedic surgeon.

J Clin Orthop Trauma

August 2024

Department of Orthopedic Surgery, Lebanese American University Medical Center-Rizk Hospital, Lebanese American University, School of Medicine, Lebanon.

Article Synopsis
  • Diabetic foot complications, like ulcers and infections, can lead to foot amputations and have a high risk of death over five years.
  • It's really important to try and save patients' feet to keep them physically and mentally healthy.
  • There are different types of surgeries that general orthopedic surgeons can do to help preserve the foot's function, and knowing when to use them is crucial for success.
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(1) Background: The Kaiser score is a user-friendly tool that evaluates lesions on breast MRI and has been studied in the general population and a few specific clinical scenarios. We aim to evaluate the performance of the Kaiser score in the characterization of additional lesions identified on staging breast MRI. (2) Methods: The Kaiser score of the biopsied additional lesions identified on staging MRI in recently diagnosed breast cancer patients was retrospectively determined.

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