447 results match your criteria: "Lead Poisoning Imaging"

Electrocardiographic changes in severe quetiapine poisoning.

Clin Toxicol (Phila)

December 2024

Department of Forensic Medicine, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima City, Hiroshima, Japan.

Introduction: Quetiapine shares sodium channel-blocking properties with tricyclic antidepressants. We present the electrographic findings in two patients with severe quetiapine poisoning.

Case Summaries: Two patients poisoned with quetiapine presented with impaired consciousness, requiring mechanical ventilation and vasopressor support, with one also experiencing status epilepticus.

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Environment and Health: Heavy Metal Toxicity.

FP Essent

October 2024

Department of Clinical Research and Public Health, Creighton University School of Medicine, Omaha, Nebraska.

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  • Focal imaging abnormalities in parkinsonism patients indicate a secondary cause, necessitating a unique diagnostic and treatment approach.
  • Various factors such as vascular issues, brain injuries, and toxic exposures can lead to secondary parkinsonism, presenting with symptoms like rigidity and bradykinesia, often without rest tremor.
  • Neuroimaging, especially MRI, is vital for diagnosis, as recognizing imaging abnormalities in context can lead to effective treatment; many secondary forms are reversible, improving our understanding of Parkinson's disease and brain function.
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Hydrogen peroxide (H₂O₂) ingestion can lead to severe systemic complications, including neurological sequelae such as acute embolic stroke. We present a case of a 49-year-old male who accidentally ingested approximately 50-60 mL of 50% w/w hydrogen peroxide, resulting in encephalopathy, upper motor neuron quadriparesis, and pulmonary artery thrombosis. The patient's altered sensorium progressed to a stupor, accompanied by acute respiratory distress and abdominal gaseous distension.

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BACKGROUND Ethanol intoxication is very common, and several forms of alcohol intoxication can lead to emergency department visits. Excessive alcohol users, when in withdrawal, might seek replacement alcoholic beverages; one of the common sources of ethanol is hand sanitizer, which contains 45-95% alcohol. It becomes even more challenging to deal with alcohol use disorder patients when they seek these replacement products inside hospital premises, and medical clinics and hospitals have increased their use of ethanol-based hand sanitizer since the start of the COVID-19 pandemic.

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Radiological changes in lead poisoning.

Clin Toxicol (Phila)

June 2024

Department of Radiology, School of Medical Sciences, University of Campinas (UNICAMP), São Paulo, Brazil.

Introduction: Lead poisoning in childhood remains an important public health concern. We highlight the radiological findings in a patient with a high blood lead concentration.

Case Summary: A 7-year-old girl presented to hospital with abdominal pain, nausea, and asthenia.

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[Febrile ciguatera with corpus callosum involvment].

Rev Med Interne

October 2024

Service de médecine interne et polyvalente, centre hospitalier de Polynésie française, 98713 Pirae, Tahiti, French Polynesia. Electronic address:

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Background: Copper exposure is reported to be associated with increased risk of stroke. However, the association of copper exposure with subclinical carotid atherosclerosis remains unclear.

Methods And Results: This observational study included consecutive participants from Xinqiao Hospital between May 2020 and August 2021.

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Rationale: Anticoagulant rodenticides (ARs) are a substantial fraction of murine types. AR poisoning causes bleeding from the skin, mucous membranes, and multiple organs. However, reports of AR-induced cerebral hemorrhage are scarce.

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This collection of images considers complex ethical, public health, and sociopolitical dimensions of firearm injuries. Since many firearm bullets contain lead, visual parallels are drawn between clinical and public health approaches to managing lead poisoning and efforts to reduce gun violence. Like lead toxicity from paint or water, gun violence and toxicity from retained ballistic fragments can adversely influence health and should be a source of concern to clinicians.

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  • Globus pallidus necrosis (GPN) is a common brain imaging finding in patients who have suffered from carbon monoxide (CO) poisoning, and current guidelines recommend imaging for those with conscious disturbances.
  • Researchers developed an artificial intelligence (AI) algorithm using a random forest classifier to predict GPN in CO intoxicated patients, analyzing data from 261 patients over a 19-year period.
  • The AI model achieved an accuracy of 79.2%, with notable predictors including platelet count, carboxyhemoglobin levels, and the Glasgow Coma scale, indicating a promising but still needing further validation approach to diagnosis.
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Tibetan medicinal materials play a significant role in Tibetan culture. However, some types of Tibetan medicinal materials share similar shapes and colors, but possess different medicinal properties and functions. The incorrect use of such medicinal materials may lead to poisoning, delayed treatment, and potentially severe consequences for patients.

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Clinical Spectrum of Mercury Poisoning in India: Case-series from a Poison Control Center.

J Assoc Physicians India

February 2023

Professor, Clinical Toxicology Unit & Poisons Information Center, Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India; Corresponding Author.

Article Synopsis
  • Mercury is a highly toxic heavy metal that exists in various forms, which can lead to serious health issues, particularly affecting the nervous, gastrointestinal, and renal systems; common exposure sources include substance use, occupational hazards, and food contamination.
  • This study aims to analyze mercury poisoning cases reported at an Indian Poison Center, focusing on the varied clinical manifestations and long-term outcomes based on the chemical type and exposure route.
  • A review of patient records revealed 22 cases of mercury exposure over two years, mostly acute, with three detailed cases highlighting the importance of understanding different effects related to exposure differences.
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Disposal of waste containing heavy metals into the environment is a major threat to human health and can result in toxic or chronic poisoning in aquatic life. In the current study, metal-resistant was isolated from metal-contaminated samples collected from the Tanjaro River, located southwest of Sulaymaniyah, Iraq. was identified by partial amplification of 16S rRNA.

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Clinical significance of fractional anisotropy in cerebral white matter regional vulnerability caused by carbon monoxide poisoning: A systematic review and meta-analysis.

Neurotoxicology

May 2023

Department of Occupational Therapy and Graduate Institute of Behavioral Sciences, Chang Gung University, Taoyuan, Taiwan; Healthy Aging Research Center, Chang Gung University, Taoyuan, Taiwan; Laboratory of Brain Imaging and Neural Dynamics (BIND Lab), Chang Gung University, Taoyuan, Taiwan; Department of Psychiatry, Chang Gung Memorial Hospital, Linkou, Taiwan. Electronic address:

Carbon monoxide poisoning (COP) can lead to various cerebral white matter (WM) lesions across different disease phases and clinical manifestations, and fractional anisotropy (FA) of diffusion tensor imaging has been widely applied to investigate WM injury in these patients. Here we conducted a systematic review and meta-analysis to investigate the utility of FA in evaluating the regional vulnerability of WM injury caused by COP and explore differences between different disease phases and patient subtypes. We systematically searched PubMed, Medline, Scopus and reference lists of appropriate publications to identify relevant studies.

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Background/aim: Inhalational methanol poisoning could cause severe damage to visual function. This study analyzed the prognosis of the correlation between the visual function and the relevant risk factors.

Methods: In this retrospective study, 14 patients had confirmed inhalational methanol poisoning, resulting in visual impairment in both eyes.

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Background: The effect of carbon monoxide (CO) poisoning on the topology of brain functional networks is unclear, especially in children whose brains are still developing.

Purpose: To investigate the topological alterations of the whole-brain functional connectome in children with CO poisoning and characterize its relationship with disease severity.

Study Type: Cross-sectional and prospective study.

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Chronic lead exposure disrupts neurometabolic activity in mouse brain: An ex vivoH-[C]-NMR study.

Neurotoxicology

January 2023

NMR Microimaging and Spectroscopy, CSIR-Centre for Cellular and Molecular Biology, Habsiguda, Uppal Road, Hyderabad 500007, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India. Electronic address:

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