17,727 results match your criteria: "Lawrence Berkeley National Laboratory; Joint Bioenergy Institute[Affiliation]"

Moiré superlattices of semiconducting transition metal dichalcogenide heterobilayers are model systems for investigating strongly correlated electronic phenomena. Specifically, WSe/WS moiré superlattices have emerged as a quantum simulator for the two-dimensional extended Hubbard model. Experimental studies of charge transport have revealed correlated Mott insulator and generalized Wigner crystal states, but spin transport of the moiré heterostructure has not yet been sufficiently explored.

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  • The study investigates how the surrounding DNA sequence affects the repair of double-stranded breaks caused by CRISPR/Cas9, using various genetically modified mouse embryonic stem cell lines.
  • Researchers analyzed over 236,000 mutation outcomes from 2800 synthetic DNA sequences, discovering specific roles of DNA repair proteins like Prkdc and Polm in generating small insertions and deletions.
  • They developed predictive models for these mutational outcomes based on their findings, enhancing the understanding of DNA repair mechanisms and enabling more accurate control of CRISPR-induced mutations.
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The high lateral resolution and sensitivity of the NanoSIMS 50 and 50L series of dynamic SIMS instruments have enabled numerous scientific advances over the past 25 years. Here, we report on the NanoSIMS-HR, the first major upgrade to the series, and analytical tests in a suite of sample types, including an aluminum sample containing silicon crystals, microalgae, and plant roots colonized with a symbiotic fungus. Significant improvements have been made in the Cs ion source, high voltage (HV) control, stage reproducibility, and other aspects of the instrument that affect performance.

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Curvilinear magnetism emerged as a new route to tailor properties of magnetic solitons by the choice of geometry and topology of a magnetic architecture. Here, we develop an anodized aluminum oxide template-based approach to realize hierarchical 3D magnetic nanoarchitectures of nanoflower shape. The technique provides defect-free regular arrays of magnetic nanoflowers of tunable shape with a period of 400 nm over cm areas.

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  • Switchgrass is a sustainable biofuel option due to its quick growth, low requirements, and high yields, but reducing its lignin content could enhance energy conversion efficiency.
  • Engineered switchgrass expressing QsuB shows decreased lignin and changes in microbial communities, with specifically lower fungal diversity in its roots and rhizosphere compared to wild-type plants.
  • The study reveals how plant metabolism changes can impact the microbiome, aiding in the development of bioengineering strategies while considering potential unintended effects on microbial interactions.
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Since the initial discovery of 2D van der Waals (vdW) materials, significant effort has been made to incorporate the three properties of magnetism, band structure topology, and strong electron correlations-to leverage emergent quantum phenomena and expand their potential applications. However, the discovery of a single vdW material that intrinsically hosts all three ingredients has remained an outstanding challenge. Here, the discovery of a Kondo-interacting topological antiferromagnet is reported in the vdW 5f electron system UOTe.

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Sex chromosomes have evolved hundreds of times across the flowering plant tree of life; their recent origins in some members of this clade can shed light on the early consequences of suppressed recombination, a crucial step in sex chromosome evolution. Amborella trichopoda, the sole species of a lineage that is sister to all other extant flowering plants, is dioecious with a young ZW sex determination system. Here we present a haplotype-resolved genome assembly, including highly contiguous assemblies of the Z and W chromosomes.

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Reducing crystal symmetry to generate out-of-plane Dzyaloshinskii-Moriya interaction.

Nat Commun

November 2024

National Laboratory of Solid State Microstructures, Department of Physics and Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing, PR China.

The Dzyaloshinskii-Moriya antisymmetric exchange interaction (DMI) stabilises topological spin textures with promising future spintronics applications. According to crystal symmetry, the DMI can be categorized as four different types that favour different chiral textures. Unlike the other three extensively-investigated types, out-of-plane DMI, as the last type that favours in-plane chirality, remained missing so far.

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The electric sector simultaneously faces two challenges: decarbonization to mitigate, and adaptation to manage, the impacts of climate change. In many regions, these challenges are compounded by an interdependence of electricity and water systems, with water needed for hydropower generation and electricity for water provision. Here, we couple detailed water and electricity system models to evaluate how the Western Interconnection grid can both adapt to climate change and develop carbon-free generation by 2050, while accounting for interactions and climate vulnerabilities of the water sector.

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Electrochemical cofactor recycling of bacterial microcompartments.

Proc Natl Acad Sci U S A

December 2024

MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing, MI 48824.

Bacterial microcompartments (BMCs) are prokaryotic organelles that consist of a protein shell which sequesters metabolic reactions in its interior. While most of the substrates and products are relatively small and can permeate the shell, many of the encapsulated enzymes require cofactors that must be regenerated inside. We have analyzed the occurrence of an enzyme previously assigned as a cobalamin (vitamin B) reductase and, curiously, found it in many unrelated BMC types that do not employ B cofactors.

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Cyanobacteria are highly abundant in the marine photic zone and primary drivers of the conversion of inorganic carbon into biomass. To date, all studied cyanobacterial lineages encode carbon fixation machinery relying upon form I Rubiscos within a CO-concentrating carboxysome. Here, we report that the uncultivated anoxic marine zone (AMZ) IB lineage of from pelagic oxygen-deficient zones (ODZs) harbors both form I and form II Rubiscos, the latter of which are typically noncarboxysomal and possess biochemical properties tuned toward low-oxygen environments.

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Conjugated ladder polymers (CLPs) are difficult yet captivating synthetic targets due to their fully unsaturated fused backbones. Inherent challenges associated with their synthesis often lead to low yields, structural defects, and insoluble products. Here a new method to form CLPs is demonstrated, utilizing a high-yielding dimerization of annulated zirconacyclopentadienes to form cyclooctatetraene (COT) monomer units.

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Article Synopsis
  • Prokaryotes utilize Bacterial Microcompartments (BMCs) to encapsulate metabolic pathways, enhancing enzyme activity for improved catalysis.
  • Sugar Phosphate Utilizing (SPU) BMCs, present in various environments from soils to hot springs, are characterized by their unique enzyme, deoxyribose 5-phosphate aldolase (DERA).
  • This study defines the key features of SPU BMCs, demonstrating the catalytic activity of DERA and its role as a signature enzyme, which could have significant implications for understanding their function and potential biotechnological uses.
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The ovary is the first organ to age in the human body, affecting both fertility and overall health. However, the biological mechanisms underlying human ovarian aging remain poorly understood. Here we present a comprehensive single-nuclei multi-omics atlas of four young (ages 23-29 years) and four reproductively aged (ages 49-54 years) human ovaries.

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In May and June of 2021, marine microbial samples were collected for DNA sequencing in East Sound, WA, USA every 4 hours for 22 days. This high temporal resolution sampling effort captured the last 3 days of a Rhizosolenia sp. bloom, the initiation and complete bloom cycle of Chaetoceros socialis (8 days), and the following bacterial bloom (2 days).

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Outdoor mesoscale fabricated ecosystems: Rationale, design, and application to evapotranspiration.

Sci Total Environ

December 2024

Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, 94720, CA, USA.

The disparity in scale, complexity, and control level between laboratory experiments and field observational studies has shaped both the methodologies employed and the nature of the research questions pursued in ecology and hydrology. While lysimeters and fabricated ecosystems suitably fit in this gap, their use as mesoscale experimental facilities has not been fully explored because of the limited manipulating capabilities and integration with imaging and monitoring methods, particularly for soil functioning. The proposed fabricated ecosystem (4.

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2025 Roadmap on 3D Nano-magnetism.

J Phys Condens Matter

November 2024

Institute of Applied Physics, Vienna University of Technology, Wiedner Hauptstr. 8-10/134, Wien, 1040, AUSTRIA.

The transition from planar (2D) to three-dimensional (3D) magnetic nanostructures represents a significant advancement in both fundamental research and practical applications, offering vast potential for next-generation technologies like ultrahigh-density storage, memory, logic, and neuromorphic computing. Despite being a relatively new field, the emergence of 3D nanomagnetism presents numerous opportunities for innovation, prompting the creation of a comprehensive roadmap by leading international researchers. This roadmap aims to facilitate collaboration and interdisciplinary dialogue to address challenges in materials science, physics, engineering, and computing.

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Reactive carbon capture (RCC) processes involve the capture of carbon dioxide (CO) and conversion to a value-added product using a single sorbent/reaction medium. Not only can RCC processes generate valuable byproducts that can reduce the cost of carbon capture, but RCC tends to have lower energy demand than processes involving the transfer of CO between the mediums used for capture and subsequent reactions. Saline water has been proposed as a potential medium for RCC due to it's relative abundance and low cost.

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Multistep Growth Pathway of Covalent Organic Framework Onion Nanostructures.

J Am Chem Soc

December 2024

Materials Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.

The growth of complex organic macromolecular materials in solution is a pervasive phenomenon in both natural and synthetic systems, yet the underlying growth mechanisms remain largely unresolved. Using liquid-phase transmission electron microscopy (TEM), we elucidate the real-time growth pathways of covalent organic framework (COF) onion nanostructures, which involve graphitic layer formation, subsequent layer attachment, onion ring closure, and structural relaxation. This process is marked by variations in orientation and curvature, driven by the dynamic formation of the COF structure, which further regulates order-disorder transition and defect generation within the framework.

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Understanding long-range opposite charge repulsion in multivalent salt solutions.

J Chem Phys

November 2024

Department of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, USA.

The electrostatic correlations between ions profoundly influence the structure and forces within electrical double layers. Here, we apply the modified Gaussian renormalized fluctuation theory to investigate the counter-intuitive phenomenon of repulsion between two oppositely charged surfaces and discuss its relationship with overcharging. By accurately accounting for the effect of spatially varying ion-ion correlations, we capture these repulsive forces for divalent, trivalent, as well as tetravalent ions, in quantitative agreement with reported simulation results.

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The tetrapod double cone is a pair of tightly associated cones called the "principal" and the "accessory" member. It is found in amphibians, reptiles, and birds, as well as monotreme and marsupial mammals but is absent in fish and eutherian mammals. To explore the potential evolutionary origins of the double cone, we analyzed single-cell and -nucleus transcriptomic atlases of photoreceptors from six vertebrate species: zebrafish, chicken, lizard, opossum, ground squirrel, and human.

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is a Gram-positive anaerobic spore-forming bacterial pathogen of humans and animals. also produces type IV pili (T4P) and has two complete sets of T4P-associated genes, one of which has been shown to produce surface pili needed for cell adherence. One hypothesis about the role of the other set of T4P genes is that they could comprise a system analogous to the type II secretion systems (TTSS) found in Gram-negative bacteria, which is used to export folded proteins from the periplasm through the outer membrane to the extracellular environment.

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Microbes display broad diversity in cobamide preferences.

bioRxiv

November 2024

Department of Plant & Microbial Biology, University of California, Berkeley, Berkeley, CA 94720, U.S.A.

Cobamides, the vitamin B (cobalamin) family of cofactors, are used by most organisms but produced by only a fraction of prokaryotes, and are thus considered key shared nutrients among microbes. Cobamides are structurally diverse, with multiple different cobamides found in most microbial communities. The ability to use different cobamides has been tested for several bacteria and microalgae, and nearly all show preferences for certain cobamides.

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Hydrophobins from mediate fungal interactions with microplastics.

bioRxiv

November 2024

Chemical and Biomolecular Engineering, University of Delaware, 150 Academy St., Newark, DE 19716.

Microplastics present myriad ecological and human health risks including serving as a vector for pathogens in human and animal food chains. However, the specific mechanisms by which pathogenic fungi colonize these microplastics have yet to be explored. In this work, we examine the opportunistic fungal pathogen, and other common soil and marine , which we found bind microplastics tightly.

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Soybean genomics research community strategic plan: A vision for 2024-2028.

Plant Genome

December 2024

USDA-ARS Corn Insects and Crop Genetics Research Unit, Ames, Iowa, USA.

This strategic plan summarizes the major accomplishments achieved in the last quinquennial by the soybean [Glycine max (L.) Merr.] genetics and genomics research community and outlines key priorities for the next 5 years (2024-2028).

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