2,930 results match your criteria: "Lahey Hospital & Medical Center[Affiliation]"

Introduction: Gender bias has been reported by women surgeons, but its impact on communication in the operating room (OR) is unclear. OR communication is critical to understand, as it directly impacts patient outcomes. The current study evaluates potential gender bias in the type and quality of communication between surgeons and OR nursing and anesthesia providers.

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Does ultrasound guidance decrease femoral access site complications in neurointerventional procedures? A retrospective cohort study.

Eur J Radiol

December 2024

The Division of Neuroradiology, Joint Department of Medical Imaging and University Medical Imaging Toronto, Toronto Western Hospital, University Health Network, 399 Bathurst Street, Toronto, Ontario M5T 2S8, Canada; Lahey Hospital & Medical Center, TH Chan School of Medicine, University of Massachusetts, Boston, United States.

Background: Ultrasound has been increasingly used to guide femoral arterial access for neuroendovascular procedures. Its effect on the safety outcomes has yet to be established.

Purpose: The purpose is to determine the effect of ultrasound-guided punctures on femoral access site complications (ASC), and to identify other potential predictors of ASC.

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Background: Long-term outcomes following left atrial appendage occlusion outside clinical trials and small registries are largely unknown. Collecting these data was a condition of US market authorization of the WATCHMAN device. The aim of this analysis was to evaluate the rates of stroke, bleeding, and death among Medicare beneficiaries following left atrial appendage occlusion implantation during initial commercial availability of the WATCHMAN left atrial appendage occlusion device overall and in important subgroups.

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Background: Until local healthcare infrastructure is strengthened, cardiac surgical care in low- and middle-income countries is often provided by non-governmental organizations by way of visiting healthcare teams. This is generally considered to be a cost-effective alternative to transporting patients to high income countries for surgical care, but the costs of cardiac surgery consumables under this model are poorly understood. Our objective was to identify the per-patient cost of cardiac surgery consumables used in single and double valve replacements performed by a non-governmental organization in Rwanda.

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Background: Aficamten is a cardiac myosin inhibitor that mitigates left ventricular outflow gradients in obstructive hypertrophic cardiomyopathy (oHCM). The clinical efficacy of aficamten across multiple outcome domains in oHCM has not been fully defined.

Objectives: This responder analysis from the SEQUOIA-HCM (Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Placebo in Adults With Symptomatic oHCM) trial characterizes the clinical impact of aficamten.

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Lung nodules are frequently detected on low-dose computed tomography scans performed for lung cancer screening and incidentally detected on imaging performed for other reasons. There is wide variability in how lung nodules are managed by general practitioners and subspecialists, with high rates of guideline-discordant care. This may be due in part to the level of evidence underlying current practice guideline recommendations (primarily based on findings from uncontrolled studies of diagnostic accuracy).

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How to utilize current guidelines to manage patients with cancer at high risk for heart failure.

Cardiooncology

September 2024

Duke Cancer Institute, Department of Medicine, Duke University, DUMC 3446, Durham, NC, 27710, USA.

Heart failure (HF) in patients with cancer is associated with high morbidity and mortality. The success of cancer therapy has resulted in an exponential rise in the population of cancer survivors, however cardiovascular disease (CVD) is now a major life limiting condition more than 5 years after cancer diagnosis [Sturgeon, Deng, Bluethmann, et al 40(48):3889-3897, 2019]. Prevention and early detection of CVD, including cardiomyopathy (CM) and HF is of paramount importance.

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Background: Women with high-risk breast lesions, such as atypical hyperplasia (AH) or lobular carcinoma in situ (LCIS), have a 4- to tenfold increased risk of breast cancer compared to women with non-proliferative breast disease. Despite high-quality data supporting chemoprevention, uptake remains low. Interventions are needed to break down barriers.

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The Fungus Among Us: Proactively Preventing Candida auris Transmission via Ultrasound Transducers.

J Ultrasound Med

January 2025

Division of Infection Control/Hospital Epidemiology, Silverman Institute for Health Care Quality and Safety, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.

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Objective: Chat-based artificial intelligence programs like ChatGPT are reimagining how patients seek information. This study aims to evaluate the quality and accuracy of ChatGPT-generated answers to common patient questions about lung cancer surgery.

Methods: A 30-question survey of patient questions about lung cancer surgery was posed to ChatGPT in July 2023.

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Article Synopsis
  • Current methods to predict sudden cardiac death (SCD) in children with hypertrophic cardiomyopathy (HCM) are insufficient, although late gadolinium enhancement (LGE) in CMR imaging has shown a link to SCD in adults.
  • This study aimed to assess the significance of LGE in HCM patients under 21 years, utilizing data from various international centers between 2015 and 2022.
  • Results indicated that 32.9% of the 700 patients had LGE, and those with LGE were more likely to experience SCD or related events, emphasizing the potential role of LGE in clinical assessments for younger patients with HCM.
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Racial disparity in peripheral nerve block usage in breast reconstruction: A nationwide analysis.

J Plast Reconstr Aesthet Surg

November 2024

Division of Plastic & Reconstructive Surgery, Department of Surgery, Lahey Hospital and Medical Center, Burlington, MA, United States. Electronic address:

Peripheral nerve block (PNB) usage in plastic surgery is associated with reduction in post-operative opioid consumption and pain demonstrating benefits in breast reconstruction (BR). This retrospective study explored whether racial-ethnic disparities exist with PNB use for postoperative analgesia in patients undergoing BR. Using the American College of Surgeons National Surgical Quality Improvement Program database, women who underwent BR from 2012-2021 and received "regional" in addition to general anesthesia were included in the study.

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Characteristics, associations, and outcomes of children with posterior segment coloboma.

J AAPOS

October 2024

Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

Purpose: To describe the clinical characteristics and outcomes of children with posterior segment coloboma (PSC).

Methods: The medical records of children (age <18 years) with PSC examined at Boston Children's Hospital from May 1997 to May 2023 were reviewed retrospectively. The following data were collected: demographics, ocular and systemic conditions, coloboma type according to the Ida Mann (IM) classification, and best-corrected visual acuity.

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Background: Recent data are inconclusive regarding the risk of arrhythmias among young cannabis users. Furthermore, many young adults use both cannabis and tobacco, which could add a residual confounding effect on outcomes. So, we studied young men who have cannabis use disorder (CUD) excluding tobacco use disorder (TUD) to understand their independent association with atrial fibrillation (AF) and related outcomes.

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Background: Gender-affirming hormone therapy (GAHT) is common among transgender individuals, but its impact on lipid profile and cardiovascular health is not well studied.

Objectives: The authors performed a systematic review and meta-analysis of existing literature to assess the impact of GAHT on lipid profiles and metabolic cardiovascular risk factors in transgender individuals.

Methods: Online databases including MEDLINE/PubMed, Embase, and Cochrane Central registry were searched to find studies on lipid profile changes in women who are transgender, also referred to as transfeminine (TF), and men who are transgender, also referred to as transmasculine (TM) before and after GAHT.

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Article Synopsis
  • Researchers evaluated the frequency of nonsustained ventricular tachycardia (NSVT) in patients with hypertrophic cardiomyopathy (HCM) using 14-day continuous ambulatory monitoring compared to traditional 48-hour monitoring.
  • Out of 236 patients, nearly half experienced NSVT over the 14 days, with a significant number only detected during the extended monitoring period, indicating that the extended monitoring greatly increased diagnostic yield by 2.7 times.
  • The findings suggest that many NSVT episodes, especially those considered higher risk, were missed in the initial 48 hours, highlighting the importance of longer monitoring periods to assess sudden death risk in HCM patients.
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More than a decade has passed since researchers in the Early Lung Cancer Action Project and the National Lung Screening Trial demonstrated the ability to save lives of high-risk individuals from lung cancer through regular screening by low dose computed tomography scan. The emergence of the most recent findings in the Dutch-Belgian lung-cancer screening trial (Nederlands-Leuvens Longkanker Screenings Onderzoek [NELSON]) further strengthens and expands on this evidence. These studies demonstrate the benefit of integrating lung cancer screening into clinical practice, yet lung cancer continues to lead cancer mortality rates in the United States.

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Cardiomyopathies in Pregnancy: Trends and Clinical Outcomes in Delivery Hospitalizations in the United States (2005-2020).

Curr Probl Cardiol

December 2024

Inova Schar Heart and Vascular, Inova Fairfax Medical Campus, Falls Church, Virginia, USA. Electronic address:

Article Synopsis
  • Cardiomyopathy (CDM) during pregnancy significantly impacts maternal health, with serious risks leading to morbidity and mortality.
  • Analysis of delivery hospitalizations from 2005-2020 showed that peripartum cardiomyopathy (PPCM) represented the majority of cases, followed closely by dilated cardiomyopathy (DCM), while hypertrophic (HCM) and restrictive cardiomyopathy (RCM) were less common.
  • PPCM was linked to the highest in-hospital mortality and adverse events, though its prevalence has decreased over time, while DCM and HCM rates have increased, highlighting a need for more research in this area.
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Introduction: Spontaneous pneumothorax is a common thoracic surgical problem. To prevent recurrence, surgical options include blebectomy, mechanical or chemical pleurodesis, pleurectomy, or a combination of these operations. Pleurectomy is associated with lower recurrence rates but may be technically challenging via video-assisted thoracoscopic surgery.

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Interactions between food and oral anticoagulants (OACs), particularly vitamin K antagonists such as warfarin, are widely recognized and may also be clinically relevant for direct OACs. Pharmacokinetic and pharmacodynamic interactions with food or herbs can lead to anticoagulation potentiation, increased risk of bleeding, or reduced drug efficacy, all compromising patient safety. We conducted a systematic search for randomized controlled trials (RCTs) on PubMed for assessments of interactions between OACs and various ingestants.

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