139 results match your criteria: "Labyrinthitis Ossificans"

Labyrinthitis ossificans is a pathology consisting of calcification of the membranous labyrinth resulting in profound sensory deafness. It is usually due to an acute inflammatory process that progresses to ossification of the labyrinth. The clinical manifestations are irreversible hearing loss, dizziness and vomiting.

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Article Synopsis
  • - The systematic review investigates vestibular dysfunction in patients with sickle cell disease (SCD), noting that while hearing loss is common, there’s limited research on balance issues related to SCD.
  • - Out of 2,495 studies reviewed, only 12 met the necessary criteria, revealing that 19% of SCD patients reported inner ear problems and 70% experienced dizziness or imbalance, particularly among older patients.
  • - The findings highlight a lack of comprehensive data and quality in existing research, pointing to a need for more studies on treatment methods and the relationship between SCD and vestibular symptoms.
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Cochlear Apex Triangulation Utilizing Ct Measures And Middle Ear Landmarks.

Otol Neurotol Open

September 2024

Department of Otolaryngology-Head and Neck Surgery, NYU Langone, New York.

Article Synopsis
  • The study aims to describe the cochlear apex's anatomy to assist surgeons during apical electrode placement for cochlear implants, enhancing procedural success.
  • Utilizing a retrospective analysis of 82 CT scans, the researchers measured distances from key middle ear landmarks to the cochlear apex, finding significant variability in anatomy.
  • A new "stapes vector" was identified as a reliable reference point for locating the cochlear apex, which could improve surgical accuracy and minimize damage during procedures.
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Labyrinthitis ossificans is the formation of pathological new bone within the membranous labyrinth of the inner ear due to various local and systemic pathologies. Most commonly it occurs as a sequelae of meningitis spreading to the labyrinth, from the subarachnoid space via the cochlear aqueduct and the internal auditory canal. We are comparing three different etiological presentations of labyrinthitis ossificans; namely, tympanogenic, meningitic, and traumatic, together with their management in the light of recent advances.

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Cochlear implantation for rare Streptococcus suis meningitis with hearing loss.

Eur Arch Otorhinolaryngol

October 2024

Department of Otolaryngology Head & Neck Surgery, Zhujiang Hospital, Southern Medical University, 253 Industrial Avenue Middle Road, Guangzhou, 510282, China.

Article Synopsis
  • This study investigated the effectiveness of 3D T2-weighted MRI and high-resolution CT scans in diagnosing cochlear fibrosis linked to Streptococcus suis meningitis.
  • Four patients with hearing loss despite antibiotic treatment were evaluated using clinical imaging and post-surgical assessments.
  • Results showed that T2MRI was more sensitive than HRCT in detecting cochlear issues, and cochlear implantation was successfully performed, indicating that CI is a viable treatment option even in severe fibrosis cases.
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Pneumococcal Meningitis Induces Hearing Loss and Cochlear Ossification Modulated by Chemokine Receptors CX3CR1 and CCR2.

J Assoc Res Otolaryngol

April 2024

Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8115, St. Louis, MO, 63110, USA.

Purpose: Pneumococcal meningitis is a major cause of hearing loss and permanent neurological impairment despite widely available antimicrobial therapies to control infection. Methods to improve hearing outcomes for those who survive bacterial meningitis remains elusive. We used a mouse model of pneumococcal meningitis to evaluate the impact of mononuclear phagocytes on hearing outcomes and cochlear ossification by altering the expression of CX3CR1 and CCR2 in these infected mice.

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Postmeningitic pediatric hearing loss from non-type b Haemophilus influenzae.

Am J Otolaryngol

December 2023

Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine, Aurora, CO, United States of America; Children's Hospital Colorado, United States of America. Electronic address:

Article Synopsis
  • Postmeningitic hearing loss in children is increasingly linked to non-type b strains of H. influenzae, particularly nontypeable strains, but this issue is not well understood.
  • A retrospective study at Children's Hospital Colorado analyzed 11 cases of nHiB H. influenzae meningitis between 2000-2020, revealing that a significant percentage of children experienced hearing loss, often associated with other serious health complications.
  • The findings suggest that administering steroids might help protect hearing after meningitis, but due to limited existing research, more studies are needed to fully understand the impact on hearing outcomes.
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Protocol for Evaluation and Management of Hearing Loss After Meningitis.

Indian J Otolaryngol Head Neck Surg

April 2023

Department of ENT and Implantation Otology, Apollo Hospitals Group, Bangalore, Karnataka 560076 India.

Article Synopsis
  • * In countries like India, challenges such as lack of awareness and resources make it crucial to optimize tests that can improve cochlear implantation success rates.
  • * The paper outlines a follow-up protocol for children post-meningitis, recommending at least two years of monitoring for hearing loss and timely cochlear implantation when necessary.
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Labyrinthitis Ossificans in a Post-Splenectomy Patient With Meningitis: A Case Report and Review of Literature.

Cureus

February 2023

Otolaryngology-Head and Neck Surgery, Massachusetts Eye and Ear, Boston, USA.

This report describes a case of cochlear implantation to treat profound deafness three months after a diagnosis of bacterial meningitis in a patient with a remote history of splenectomy. A 71-year-old woman with a remote history of a splenectomy over 20 years before presented with bilateral profound deafness that occurred as sequela from pneumococcal meningitis three months prior. The patient had been vaccinated against the 23-valent polysaccharide pneumococcal vaccine (PPV-23).

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Cochlear Implant Induced Labyrinthine Ossificans in Mondini Malformation: A Case Series.

Cureus

December 2022

Otorhinolaryngology - Head and Neck, King Abdullah Ear Specialist Centre (KAESC) King Abdulaziz University Hospital, King Saud University, Riyadh, SAU.

Article Synopsis
  • Cochlear implantation is generally safe and has good success rates, although complications can arise.
  • Labyrinthine ossification is a rare issue that may occur after the procedure, leading to complications such as implant failure.
  • This paper discusses two specific cases of cochlear implant failures linked to labyrinthine ossification and reviews existing literature on risk factors and strategies to prevent and address this complication.
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Objective: While the implications of ossification on cochlear implantation (CI) have been extensively described, there is a paucity of data regarding the fibrotic stage. We examined the outcomes of different insertion techniques for managing intracochlear fibrosis.

Study Design: Retrospective review of case series with case-control comparison.

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Management and long-term comorbidities of patients with necrotizing otitis externa.

Eur Arch Otorhinolaryngol

June 2023

Department of Head Neck Surgery, Tepecik Training and Research Hospital, Health Science University, Izmir Tepecik SUAM Gaziler Bulvarı No:468, Yenisehir, Konak, Izmir, Turkey.

Article Synopsis
  • The study focused on managing necrotizing otitis externa (NOE) patients and their related health issues over both short and long periods from 2011 to 2022.
  • Out of 30 patients observed (mostly older men), there was a significant mortality rate of 23.33%, and common complications included severe hearing loss and other serious health conditions like chronic anemia and cerebrovascular diseases.
  • The findings highlighted that NOE requires ongoing treatment, especially for those with medial skull base involvement, which correlates with more severe complications such as cranial nerve paralysis and labyrinthitis ossificans.
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Objective: To characterize our experience with super-absorbent polymer beads placed in the external auditory canal to better understand the damage caused and subsequent management required.

Methods: Retrospective chart review of pediatric patients at 2 separate tertiary referral centers.

Results: Seven patients were identified as having placed super-absorbent polymer beads in the external auditory canal, 6 of whom required removal under general anesthesia.

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Robotic cochlear implantation in post-meningitis ossified cochlea.

Am J Otolaryngol

December 2022

Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Department of Otolaryngology Head and Neck surgery, Laarbeeklaan 101, Brussels Health Campus, 1090 Brussels, Belgium.

Article Synopsis
  • This study reports on the use of a robot arm during cochlear implantation surgery for a 55-year-old man with severe hearing loss due to labyrinthitis ossificans.
  • The robotic-assisted surgery employed a flexible electrode and focused on achieving optimal depth of insertion while navigating challenges posed by intra-cochlear ossifications.
  • The findings suggest that combining radiological imaging with robotic navigation can enhance access to the inner ear, improving the likelihood of successful cochlear implant procedures.
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High resolution computed tomography (HRCT) is a tool which provide fine details of temporal bone and its associated pathologies which are of extreme use in making diagnosis, to evaluate extension of disease and most important to plan surgical approach. Aim of the present study was to correlate HRCT findings with operative findings in different ear pathologies. This observational, prospective study enrolled 70 patients of different ear pathologies required surgical intervention.

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Article Synopsis
  • The study focuses on the histologic features of labyrinthitis ossificans (LO) obtained from a surgical sample, unlike previous research which primarily used postmortem samples.
  • A 38-year-old woman with symptoms of vertigo and hearing loss underwent labyrinthectomy and cochlear implantation, which was preceded by imaging tests that confirmed isolated LO.
  • Results showed significant improvement in hearing post-surgery, with histological analysis revealing fibrosis and ossification, suggesting that treatments for heterotopic ossification might also be relevant for preventing LO.
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Inner ear modifications in Dar-es-Soltane II H5 (Morocco): A case of labyrinthitis ossificans.

Int J Paleopathol

September 2022

Collège de France, Paris, France; Dept. of Human Evolution, Max Planck Institute for Evolutionary Anthropology MPI-EVA), Leipzig, Germany. Electronic address:

Objective: This paper presents the inner ear modifications in Dar-es-Soltane II H5, an Aterian fossil possibly dated to 100 ka.

Material: The remains consist of a large portion of the cranium including the face, the left frontal and temporal bones, part of the left parietal bone and greater wing of the sphenoid.

Methods: The bony labyrinth anatomy was investigated on existing micro-CT data acquired by the MPI-EVA.

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Labyrinthitis occurs because of the inflammation of the inner ear. We present a rare case of labyrinthitis ossificans following an acute otitis media. The T2-weighted magnetic resonance imaging showed decreased signal intensity in the right inner ear due to labyrinthitis ossificans, consistent with the clinical presentation.

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Article Synopsis
  • The study aimed to assess the long-term success of cochlear implants in patients who became deaf after bacterial meningitis and compare their outcomes with those of patients who were deaf for other reasons.
  • The research involved reviewing records of 54 post-meningitic patients and comparing them with 54 control patients of similar demographics, focusing on surgical outcomes and auditory performance scores.
  • Results indicated that post-meningitic patients had significantly poorer auditory performance outcomes compared to controls, though the presence of labyrinthitis ossificans did not affect the final performance scores.
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Objective: Conventional cochlear implants provide patients who are deaf with hearing via electrical intracochlear stimulations. Stimulation electrodes are inserted into the cochlea through a cochleostomy or round window membrane (RWM) approach. However, these methods might induce cochlear ossificans and loss of residual hearing by damaging inner ear structures.

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