8 results match your criteria: "Laboratory of Clinical Studies and Basic Models of Spinal Disorders[Affiliation]"

Hypofractionated Stereotactic Radiosurgery and Radiotherapy to Large Resection Cavity of Metastatic Brain Tumors.

World Neurosurg

January 2017

Department of Radiation Oncology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; Brain Research Institute, David Geffen School of Medicine at UCLA, Los Angeles, California, USA; Neuroscience Interdepartmental Program, David Geffen School of Medicine at UCLA, Los Angeles, California, USA. Electronic address:

Objective: To evaluate the efficacy of postoperative fractionated stereotactic radiosurgery (FSRS) and hypofractionated stereotactic radiotherapy (SRT) to large surgical cavities after gross total resection of brain metastases.

Methods: A retrospective analysis of 41 patients who had received tumor-bed FSRS (5 fractions) or SRT (10 fractions) after resection of brain metastasis between 2005 and 2015 was performed. All resection cavities were treated with a frameless linear accelerator-based system.

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Background: The number and quality of scientific publications reflects the standards of scientific research in a country. However, the contribution of Indian spine surgeons toward global publications is unknown. The goal is to study the publications of Indian spine surgeons between 2000 and 2013.

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A 28-year-old man presented to the emergency room with a severe headache of one day's duration. A computerized tomography scan showed a hemorrhagic tumor measuring 3.9 x 4.

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Background: Current international guidelines do not recommend the routine administration of methylprednisolone (MP) in patients with acute spinal cord injury (SCI). Its use is known to be associated with complications and death.

Objectives: To identify patterns of practice and reasons for MP prescription for acute SCI in Latin America.

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Introduction: The state of value-based management of spinal disorders and ongoing Brazilian strategies toward its implementation are highlighted in this article.

Methods: The health care system, economic impact of spine surgery, use of patient-reported outcomes, ongoing studies about health economics, and current strategies toward implementation of quality assessment of spine care in Brazil are reviewed.

Results: During the past 20 years, there has been an increase of 226% in the number and 540% in the total cost of spine surgeries in the public health system.

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Background: Over the last decade, the growing body of work on spine pathology has led to developments and refinements in the areas of basic science, diagnosis and treatment of a variety of spine conditions. Scientific publications have a global impact on the international scientific community as they share vital information that can be applied by physicians worldwide to solve their everyday medical problems. The historical background of scientific publication in journals in Japan on the subject of spine is unclear.

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Article Synopsis
  • Lumbar discectomy is a common spine surgery, and a study evaluated its cost-effectiveness in Brazil, measuring costs per quality-adjusted life year (QALY) gained.
  • The study involved 143 patients and accounted for direct medical costs (around R$5,454, or $2,272) and indirect costs, finding a QALY gain of approximately 0.177 over four years.
  • The estimated cost-utility ratio for the procedure was about R$30,828 ($12,845) per QALY, indicating it provides significant patient outcome improvements.
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