1 results match your criteria: "Laboratory of Clinical Pharmacology and Prescriptive Appropriateness[Affiliation]"
Relation between drug therapy-based comorbidity indices, Charlson's comorbidity index, polypharmacy and mortality in three samples of older adults.
Arch Gerontol Geriatr
April 2022
Laboratory of Clinical Pharmacology and Prescriptive Appropriateness, Istituto di Ricerche Farmacologiche Mario Negri IRCCS, Via Mario Negri 2, Milan 20156, Italy.
Article Synopsis
- Comorbidity indices, like Charlson's Comorbidity Index (CCI) and therapy-based indices, are used to assess disease burden and predict patient outcomes, particularly mortality in older adults.
- A study evaluated the effectiveness of these indices and the role of polypharmacy to predict one-year mortality using data from three Italian cohorts, including nursing home residents and older patients admitted to hospitals.
- Results showed that while higher CCI scores were linked to increased mortality risk, the predictive accuracy of all comorbidity indices was generally low, indicating these tools are not very effective across different patient populations.