1 results match your criteria: "Labafi Nedjad Hospital[Affiliation]"
17β-Estradiol Stimulates Generation of Reactive Species Oxygen and Nitric Oxide in Ovarian Adenocarcinoma Cells (OVCAR 3).
Iran J Cancer Prev
May 2015
Departement of Laboratory, Labafi Nedjad Hospital, Social Security Organization, Tehran, IR Iran.
Background: Experimental and epidemiological evidence supports a role for steroid hormones in the pathogenesis of ovarian cancer. Among steroid hormones, 17β-estradiol (E2) has the most potent effect on proliferation, apoptosis and metastasis.
Objectives: In the present study, we investigated the effect of E2 on production of ROS and NO in ovarian cancer cells.