1 results match your criteria: "La Timone University Teaching Hospital. bertrand.pourroy@ap-hm.fr.[Affiliation]"
Visual compatibility of defibrotide with selected drugs during simulated Y-site administration.
Am J Health Syst Pharm
August 2014
Florian Correard is Pharmacy Intern; Amandine Savry, Pharm.D., Ph.D., is Pharmacist; and Laurence Gauthier-Villano, Pharm.D., is Pharmacist, Oncopharma Unit, Pharmacy Department, La Timone University Teaching Hospital, Marseille, France. Pascale Pisano, Pharm.D., Ph.D., is Pharmacist, Pharmacology Laboratory and Faculty of Pharmacy, Aix Marseille University, Marseille. Bertrand Pourroy, Pharm.D., Ph.D., is Pharmacist, Oncopharma Unit, Pharmacy Department, La Timone University Teaching Hospital.
Purpose: The visual compatibility of a solution of defibrotide (the only drug recommended for treatment and prophylaxis of hepatic venoocclusive disease) with solutions of various drugs commonly administered in bone marrow transplant procedures was studied.
Methods: Solutions of 43 drug products in concentrations typically used in clinical practice were evaluated in 1:1 mixtures with defibrotide solution in glass tubes kept at room temperature. The evaluated products included antiinfectious, corticoid, sedative, analgesic, and cardiovascular agents widely used for hematopoietic stem cell transplantation and other marrow transplant procedures; in most cases, test solutions were prepared via dilution in or reconstitution with sterile water, 0.