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Concordance between platelet counts by impedance and optical technique during microcytic anemia: towards a threshold value of the mean corpuscular volume.
Tunis Med
June 2024
La Rabta University Hospital Center, Hematology department, Tunis, Tunisia.
Article Synopsis
- Platelet count is essential for clinical decisions, but the impedance technique (PLT-I) may overestimate counts in cases of microcytosis, prompting a comparison with the optical technique (PLT-O).
- A study analyzed blood samples with microcytosis (MCV<80 fL) and found a strong correlation between PLT-I and PLT-O for platelet values below 150 x 10^9/L, though a bias of 16.53 x 10^9/L was noted.
- The research suggests that while impedance can be used routinely, the optical technique should be used for samples with MCV<72.9 fL or when schizocytes are present to ensure accurate hemogram validation.