2 results match your criteria: "La Paz Hospital Health Research Institute-IdiPAZ[Affiliation]"

The treatment of small to moderate size defects in revision total knee arthroplasty (rTKA) has yielded good results with various techniques (cement and screws, small metal augments, impaction bone grafting and modular stems). However, the treatment of severe defects remains problematic.Severe defects have typically been treated with large allograft and metaphyseal sleeves.

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Article Synopsis
  • Cutaneous adverse drug reactions (ADRs) are unpredictable skin conditions with varying severity, including serious ones known as severe cutaneous adverse reactions (SCARs), such as AGEP, DRESS, SJS, and TEN.
  • These SCARs are delayed-type IV hypersensitivity reactions driven by a T-cell-mediated immune response, where various T-cell subpopulations like CTLs and Th cells contribute to the immune process.
  • Interactions among different immune cells, including both adaptive and innate immune systems, as well as genetic and environmental factors, influence the variability and development of SCAR phenotypes, though the exact mechanisms are not fully understood yet.
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